Lene Jørgensen

Lene Jørgensen

Associate Professor

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    1. Published

      Liposomer i lægemiddelforskning

      Franzen, U., Jørgensen, Lene, Larsen, C. S., Jensen, H. & Østergaard, Jesper, 2007, In: Lægemiddelforskning. p. 14-15

      Research output: Contribution to journal › Journal article › Communication

    2. Published

      Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation

      Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: effects of hydrogen bonding and α-chirality in the β-peptoid residues

      Jing, X., Yang, M., Kasimova, M. R., Malmsten, M., Franzyk, Henrik, Jørgensen, Lene, Foged, Camilla & Nielsen, Hanne Mørck, 2012, In: BBA General Subjects. 1818, 11, p. 2660-2668 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Metode til screening af modificerede proteinlægemidler under opbevaring

      Petersen, C., Jørgensen, Lene, Hostrup, S., Bukrinsky, J. T. & Frøkjær, Sven, 2008, In: Lægemiddelforskning. p. 16-18

      Research output: Contribution to journal › Journal article › Communication

    5. Published

      Micropipette manipulation a technique to evaluate the stability of water-in-oil emulsions containing proteins

      Jørgensen, Lene, Kim, D. H., Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Pharmaceutical Sciences. 93, 12, p. 2994-3003

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Multivariate analysis of protein physical stability

      Guzman, P., Jørgensen, Lene, Strachan, C., Rades, T. & Medlicott, N., 2010.

      Research output: Contribution to conference › Conference abstract for conference › Research

    7. Published

      Penetration of gel and liquid state liposomes into barrier-impaired skin

      Knudsen, N. Ø., Frøkjær, Sven, Hansen, J., Jørgensen, Lene & Foged, Camilla, 2010, In: Journal of Pharmacy and Pharmacology. p. 793

      Research output: Contribution to journal › Conference article › Research › peer-review

    8. Published

      Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles

      Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Probing structural changes of proteins incorporated into water-in-oil emulsions

      Jørgensen, Lene, van de Weert, Marco, Vermehren, C., Bjerregaard, S. & Frøkjær, Sven, Jul 2004, In: Journal of Pharmaceutical Sciences. 93, 7, p. 1847-59 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Protease and amylase stability in the presence of chelators used in laundry detergent applications: correlation between chelator properties and enzyme stability in liquid detergents

      Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, 3, p. 265-276

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence  (TIRF)

      Jørgensen, Lene, Krøyer Wood, G., Rosenkrands, I., Petersen, C. & Christensen, D., 2009, In: Journal of Liposome Research. 19, 2, p. 99-104

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation

      Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation

      Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains

      Mohd Hidzir, N., Anitha, A., Kepa, K., Hill, D. J. T., Jørgensen, Lene & Grondahl, L., 2020, In: Biointerphases. 15, 3, 11 p., 031011.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Protein antigen adsorption to the DDA/TDB liposomal adjuvant: effect on protein structure, stability, and liposome physicochemical characteristics

      Hamborg, M., Jørgensen, Lene, Bojsen, A. R., Christensen, D. & Foged, Camilla, 2013, In: Pharmaceutical Research. 30, 1, p. 140-55 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Protein nanopharmaceuticals - concepts and safety considerations

      Møller, E. H., Jørgensen, Lene & Medlicott, N. J., 2013, Nanopharmaceutics: the potential application of nanomaterials. Liang, X-J. (ed.). Singapore: World Scientific, p. 49-

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    17. Published

      Proteiner i lægemidler - de sætter sig alle de forkerte steder

      Baldursdóttir, S. G., Nielsen, S. H., Fullerton, M. & Jørgensen, Lene, 2010, In: Lægemiddelforskning. 2010, p. 43-45

      Research output: Contribution to journal › Journal article › Research

    18. Published

      Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients

      Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230

      Research output: Contribution to journal › Review › Research

    19. Published

      Responsive gelation of hydrophobized linear polymer

      Madsen, C. G., Toeth, J., Jørgensen, Lene, Hietala, S., Baldursdottir, S. G. & Hietala, S., 2014. 4 p.

      Research output: Contribution to conference › Paper › Research

    20. Published

      Rheological Characterization of Lysozyme Adsorption to Oil-Water Interface Using Double Wall Ring Geometry

      Baldursdottir, S. G. & Jørgensen, Lene, 2012.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    21. Published

      Screening of formulation parameters for stabilizing recombinant human serum albumin (rHSA) in liquid formulations

      Baldursdottir, S., Tauhaybeche, M., Pekka Pajander, J., Bukrinski, J. T. & Jørgensen, Lene, Aug 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 1-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Screening of novel excipients for freeze-dried protein formulations

      Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity

      Lobbens, E. S. B., Vissing, K. J., Jørgensen, Lene, van de Weert, Marco & Jäger, A. K., 22 Mar 2017, In: Journal of Ethnopharmacology. 200, p. 66-73 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Secondary structure alteration in insulin and growth hormone water-in-oil emulsions

      Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2003, In: Internation Journal of Pharmaceutics. 254, 1, p. 7-10

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity

      Madsen, C. G., Skov, A., Baldursdottir, S., Rades, Thomas, Jørgensen, Lene & Medlicott, N. J., 7 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 1-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

      Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

      Christensen, J. R., Meng-Lund, H., Grohganz, Holger, Poso, A., Laitinen, T., Korhonen, O., Jørgensen, Lene & Pajander, J., 1 May 2017, In: European Journal of Pharmaceutical Sciences. 102, p. 188-195 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity

      Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, p. 478-485

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin

      Lobbens, E. S., Foderà, Vito, Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, Lene & van de Weert, Marco, 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      The challenges in and importance of analysing protein structure and physical stability in complex formulations

      Jørgensen, Lene, Jensen, M. G., Roest, N., Pinholt, C. & van de Weert, Marco, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 347-353 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    31. Published

      The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations ?

      Pinholt, C., Hartvig, R. A., Medlicott, N. J. & Jørgensen, Lene, 2011, In: Expert Opinion on Drug Delivery. 8, 7, p. 949-964

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      The influence of size, structure and hydrophilicity of model surfactants on the adsorption of lysozyme to oil-water interface-Interacial shear measurements

      Baldursdóttir, S. G. & Jørgensen, Lene, 2011, In: Colloids and Surfaces B: Biointerfaces. 87, p. 96-102

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      The physical stability of the recombinant tuberculosis fusion antigens h1 and h56

      Hamborg, M., Kramer, R., Schanté, C. E., Agger, E. M., Christensen, D., Jørgensen, Lene, Foged, Camilla & Middaugh, C. R., Oct 2013, In: Journal of Pharmaceutical Sciences. 102, 10, p. 3567-78 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Towards the understanding of complex fluids in pharmaceutical sciences

      Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      pH dependent polymer surfactants for hindering BSA adsorption to oil-water interface

      Colak, S., Guzman, P., Medlicott, N., Tehnu, H., Niskanen , J., Alhoranta, A., Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 329-334

      Research output: Contribution to journal › Conference article › Research

    36. Published

       Adsorption of proteins at the oil/water inerface - observation of protein adsorption by interfacial shear stress measurements

      Baldursdóttir, S. G., Fullerton, M. S., Nielsen, S. H. & Jørgensen, Lene, 2010, In: Colloids and Surfaces B: Biointerfaces. 79, p. 41-46

      Research output: Contribution to journal › Journal article › Research › peer-review

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