Toxicology and Drug Metabolism

Read more
1 - 50 out of 127Page size: 50
  1. 2024
  2. Published

    Ablative fractional laser treatment reduces hedgehog pathway gene expression in murine basal cell carcinomas

    Pedersen, K. K., Granborg, J. R., Lerche, Catharina Margrethe, Litman, Thomas, Olesen, U. H. & Hædersdal, Merete, 2024, In: Lasers in Medical Science. 39, 1, 9 p., 55.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration

    Westgate, C. S. J., Kamp-Jensen, C., Israelsen, I. M. E., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C. A., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rigmor Højland & Eftekhari, S., 2024, In: British Journal of Pharmacology. 181, 1, p. 70-86

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Ancient forest plants possess cytotoxic properties causing liver cancer HepG2 cell apoptosis

    Yue, X., Ling Ma, N., Zhong, J., Yang, H., Chen, H., Yang, Y., Lam, S. S., Yan, L., Styrishave, Bjarne, Ciesielski, T. M., Peng, W. X. & Sonne, C., 2024, In: Environmental Research. 241, 9 p., 117474.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Anti-PD-1 immunotherapy with adjuvant ablative fractional laser displays increased tumour clearance of squamous cell carcinoma, a murine study

    Christensen, R. L., Wiinberg, M., Lerche, Catharina Margrethe, Demehri, S., Olesen, U. H. & Hædersdal, Merete, 2024, In: Experimental Dermatology. 33, 2, 9 p., e15013.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension

    Wardman, Jonathan Henry, Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Jensen, Mette Nyholm, Wilhjelm, J. E., Styrishave, Bjarne, Hamann, Steffen, Heegaard, Steffen, Sinclair, A. J. & MacAulay, Nanna, 2024, In: Fluids and Barriers of the CNS. 21, 1, 20 p., 10.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Exposure to topiramate and acetazolamide causes endocrine disrupting effects in female rats during estrus

    Kamp-Jensen, Christina, Donslund, L. N., Styrishave, Bjarne, Jensen, Rigmor Højland & Westgate, C. S. J., 2024, In: Toxicology and Applied Pharmacology. 486, 11 p., 116919.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Oral administration of quercetin and fisetin potentiates photocarcinogenesis in UVR-exposed hairless mice

    Pihl, Celina, Granborg, J. R., Pinto, F. E., Bjerring, P., Andersen, F., Janfelt, Christian, Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Phytomedicine Plus. 4, 2, 8 p., 100547.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Oral intake of bucillamine, carvedilol, metformin, or phenformin does not protect against UVR-induced squamous cell carcinomas in hairless mice

    Pihl, Celina, Bjerring, P., Andersen, F., Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Photochemical and Photobiological Sciences. 23, p. 517-526

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The intrafollicular concentrations of biologically active cortisol in women rise abruptly shortly before ovulation and follicular rupture

    Johannsen, Malene Louise, Poulsen, L. C., Mamsen, L. S., Grøndahl, M. L., Englund, A. L. M., Lauritsen, N. L., Carstensen, E. C., Styrishave, Bjarne & tcg964, tcg964, 2024, In: Human Reproduction. 39, 3, p. 578-585

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Accepted/In press

    Urinary thymidine dimer excretion reflects personal ultraviolet radiation exposure levels

    Lerche, Catharina Margrethe, Frederiksen, N. J. S., Thorsteinsson, I. S., Køster, B., Nybo, Lars, Flouris, A. D., Heydenreich, J., Philipsen, P. A., Hædersdal, Merete, Wulf, H. C. & Granborg, J. R., 2024, (Accepted/In press) In: Photochemical and Photobiological Sciences.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2023
  13. Published

    A New Ellagic Acid Rhamnoside from Synadenium glaucescens and Its Cytotoxicity Evaluation

    Rwegoshora, F., Mabiki, F., Machumi, F., Chacha, M., Styrishave, Bjarne & Cornett, Claus, 2023, In: Chemistry of Natural Compounds. 59, 4, p. 670-674

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A randomized, placebo-controlled, trial to assess the photosensitizing, phototoxic and carcinogenic potential of hydrochlorothiazide in healthy volunteers

    Götzinger, F., Hohl, M., Lauder, L., Millenaar, D., Kunz, M., Meyer, M. R., Ukena, C., Lerche, Catharina Margrethe, Philipsen, P. A., Reichrath, J., Böhm, M. & Mahfoud, F., 2023, In: Journal of Hypertension. 41, 11, p. 1853-1862

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Comparison of global DNA methylation analysis by whole genome bisulfite sequencing and the Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis

    Meyer, Olivia Luxford, Andersen, M. M., Børsting, Claus, Morling, Niels, Wulf, H. C., Philipsen, P. A., Lerche, Catharina Margrethe & Andersen, Jeppe Dyrberg, 2023, In: Epigenetics. 18, 1, 10 p., 2144574 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Cycle-dependent sex differences in expression of membrane proteins involved in cerebrospinal fluid secretion at rat choroid plexus

    Israelsen, I. M. E., Kamp-Jensen, C., Westgate, C. S. J., Styrishave, Bjarne, Jensen, Rigmor Højland & Eftekhari, S., 2023, In: BMC Neuroscience. 24, 1, 11 p., 60.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Does systemic hydrochlorothiazide increase the risk of developing ultraviolet radiation-induced skin tumours in hairless mice?

    Lerche, Catharina Margrethe, Al-Chaer, R. N. & Wulf, H. C., 2023, In: Experimental Dermatology. 32, 4, p. 341-347

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effects of empagliflozin on erythropoiesis in heart failure: data from the Empire HF trial

    Fuchs Andersen, C., Omar, M., Glenthøj, Andreas Birkedal, Fassi, Daniel El , Møller, H. J., Kurtzhals, Jørgen, Styrishave, Bjarne, Kistorp, Caroline Michaela Nervil, Tuxen, C., Poulsen, M. K., Faber, Jens, Køber, Lars Valeur, Gustafsson, Finn, Møller, J. E., Schou, Morten & Jensen, J., 2023, In: European Journal of Heart Failure. 25, 2, p. 226-234

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Elucidating the spatial distribution of organic contaminants and their biotransformation products in amphipod tissue by MALDI- and DESI-MS-imaging

    Raths, J., Pinto, F. E., Janfelt, Christian & Hollender, J., 2023, In: Ecotoxicology and Environmental Safety. 264, 10 p., 115468.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria: A systematic review

    Heerfordt, I. M., Lerche, Catharina Margrethe, Philipsen, P. A. & Wulf, H. C., 2023, In: Biomedicine and Pharmacotherapy. 158, 11 p., 114132.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    FK506-Binding Protein 2 Participates in Proinsulin Folding

    Hoefner, C., Bryde, T. H., Pihl, C., Tiedemann, S. N., Bresson, S. E., Hotiana, H. A., Khilji, M. S., Santos, T. D., Puglia, M., Pisano, P., Majewska, M., Durzynska, J., Klindt, K., Klusek, J., Perone, M. J., Bucki, R., Hägglund, P. M., Gourdon, P. E., Gotfryd, K., Urbaniak, E. & 5 others, Borowiak, M., Wierer, M., MacDonald, P. E., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, 2023, In: Biomolecules. 13, 1, 20 p., 152.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    High-throughput screening of ancient forest plant extracts shows cytotoxicity towards triple-negative breast cancer

    Li, Y., Ling Ma, N., Chen, H., Zhong, J., Zhang, D., Peng, W., Shiung Lam, S., Yang, Y., Yue, X., Yan, L., Wang, T., Styrishave, Bjarne, Maciej Ciesielski, T. & Sonne, C., 2023, In: Environment International. 181, 10 p., 108279.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Importance of Dietary Uptake for in Situ Bioaccumulation of Systemic Fungicides Using Gammarus pulex as a Model Organism

    Raths, J., Schnurr, J., Bundschuh, M., Pinto, F. E., Janfelt, Christian & Hollender, J., 2023, In: Environmental Toxicology and Chemistry. 42, 9, p. 1993-2006

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid

    Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, Janfelt, Christian, Kornum, Birgitte Rahbek & Kristensen, Jesper Langgaard, 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Leaves of Cannabis sativa and their trichomes studied by DESI and MALDI mass spectrometry imaging for their contents of cannabinoids and flavonoids

    Lorensen, Marcus Daniel B B, Hayat, S. Y., Wellner, N., Bjarnholt, Nanna & Janfelt, Christian, 2023, In: Phytochemical Analysis. 34, 3, p. 269-279

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

    Wardman, Jonathan Henry, Jensen, Mette Nyholm, Andreassen, Søren Norge, Styrishave, Bjarne, Wilhjelm, J. E., Sinclair, A. J. & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 44.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mucoadhesive chitosan- and cellulose derivative-based nanofiber-on-foam-on-film system for non-invasive peptide delivery

    Stie, Mai Bay, Öblom, H., Hansen, Anders Christian Nørgaard, Jacobsen, Jette, Chronakis, I. S., Rantanen, Jukka, Nielsen, Hanne Mørck & Genina, Natalja, 2023, In: Carbohydrate Polymers. 303, 120429.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Optimization of HPLC–MS/MS method for determination of antimalarial adulterants in herbal products

    Mwankuna, C. J., Kiros, F., Mariki, E. E., Mabiki, F. P., Malebo, H. M., Mdegela, R. H. & Styrishave, Bjarne, 2023, In: Analytical Sciences. 39, p. 407-416

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Accepted/In press

    Oral Squamous Cell Carcinoma Lipid Evaluation in Gingiva Tissue Stored in TRIzol via Shotgun Lipidomics and MALDI Mass Spectrometry Imaging

    Bernardo, R. A., de Oliveira Júnior, C. I., Roque, J. V., Costa, N. D. L., Roriz, V. M., Sorgi, C. A., Janfelt, Christian, Vaz, B. G. & Chaves, A. R., 2023, (Accepted/In press) In: Journal of Proteome Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Oral phytochemicals as photoprotectants in UVR exposed hairless mice: A study of hesperidin methyl chalcone, phloroglucinol, and syringic acid

    Pihl, Celina, Bendtsen, K. M. S., Jensen, Henrik Elvang, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2023, In: Journal of Photochemistry and Photobiology B: Biology. 246, 112760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Phototesting in erythropoietic protoporphyria trials: A systematic review

    Heerfordt, I. M., Philipsen, P. A., Lerche, Catharina Margrethe & Wulf, H. C., 2023, In: Experimental Dermatology. 32, 7, p. 1042-1047

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Protection against visible light by dihydroxyacetone in erythropoietic protoporphyria

    Heerfordt, I. M., Philipsen, P. A., Lerche, Catharina Margrethe & Wulf, H. C., 2023, In: Photodiagnosis and Photodynamic Therapy. 41, 5 p., 103302.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Repeated exposure to fractional CO2 laser delays squamous cell carcinoma formation and prevents clinical and subclinical photodamage visualized by line-field confocal optical coherence tomography and histology

    Olesen, U. H., Jacobsen, K., Lerche, Catharina Margrethe & Hædersdal, Merete, 2023, In: Lasers in Surgery and Medicine. 55, 1, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry imaging

    Lorensen, Marcus Daniel B B, Bjarnholt, Nanna, St-Pierre, B., Heinicke, S., Courdavault, V., O'Connor, S. & Janfelt, Christian, 2023, In: Phytochemistry. 209, 15 p., 113620.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Testosterone and persistent organic pollutants in East Greenland male polar bears (Ursus maritimus)

    Ciesielski, T. M., Sonne, C., Smette, E. I., Villanger, G. D., Styrishave, Bjarne, Letcher, R. J., Hitchcock, D. J., Dietz, R. & Jenssen, B. M., 2023, In: Heliyon. 9, 3, 10 p., e13263.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids

    Stander, E. A., Lehka, B., Carqueijeiro, I., Cuello, C., Hansson, F. G., Jansen, H. J., Dugé De Bernonville, T., Birer Williams, C., Vergès, V., Lezin, E., Lorensen, M. D. B. B., Dang, T. T., Oudin, A., Lanoue, A., Durand, M., Giglioli-Guivarc’h, N., Janfelt, C., Papon, N., Dirks, R. P., O’connor, S. E. & 3 others, Jensen, M. K., Besseau, S. & Courdavault, V., 2023, In: Communications Biology . 6, 1, 19 p., 1197.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The aerial epidermis is a major site of quinolizidine alkaloid biosynthesis in narrow-leafed lupin

    Frick, Karen Michiko, Lorensen, Marcus Daniel B B, Esteban, E., Pasha, A., Schulz, Alexander, Provart, N. J., Janfelt, Christian, Nour-Eldin, Hussam Hassan & Geu-Flores, Fernando, 2023, bioRxiv, 18 p.

    Research output: Working paper › Preprint › Research

  38. Published

    Thin Layer Chromatographic Method for Detection of Conventional Drug Adulterants in Herbal Products

    Mwankuna, C. J., Mariki, E. E., Mabiki, F. P., Malebo, H. M., Styrishave, Bjarne & Mdegela, R. H., 2023, In: Separations. 10, 1, 10 p., 23.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Tissue-specific stilbene accumulation is an early response to wounding/grafting as revealed by using spatial and temporal metabolomics

    Loupit, G., Fonayet, J. V., Lorensen, Marcus Daniel B B, Franc, C., De Revel, G., Janfelt, Christian & Cookson, S. J., 2023, In: Plant Cell and Environment. 46, 12, p. 3871-3886

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Towards a microfluidic H295R steroidogenesis assay—biocompatibility study and steroid detection on a thiol-ene-based chip

    Despicht, C., Munkboel, C. H., Chou, H. N., Ertl, P., Rothbauer, M., Kutter, Jörg P., Styrishave, Bjarne & Kretschmann, A., 2023, In: Analytical and Bioanalytical Chemistry. 415, p. 5421–5436

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Variation in oligosaccharide profiles observed with AP-MALDI in different regions of maize kernels after treatment with xylanases

    Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2023, In: Journal of Cereal Science. 109, 10 p., 103586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2022
  43. Published

    A HPLC-MS/MS method for screening of selected antibiotic adulterants in herbal drugs

    Mwankuna, C. J., Uwamaliya, G. A., Mariki, E. E., Mabiki, F., Malebo, H. M., Mdegela, R. & Styrishave, Bjarne, 2022, In: Analytical Methods. 14, 10, p. 1060-1068

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars: A blinded randomized controlled trial

    Erlendsson, A. M., Rosenberg, L. K., Lerche, Catharina Margrethe, Togsverd-Bo, K., Wiegell, Stine Regin, Karmisholt, Katrine Elisabeth, Philipsen, P. A., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Holmes, J., Rossi, A. & Hædersdal, Merete, 2022, In: Lasers in Surgery and Medicine. 54, 5, p. 663-671

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Anti-Newcastle Disease Virus activity of 3β and 3α Friedelanol Triterpenoids from the leaves of Synadenium glaucescens Pax

    Credo, D., Mabiki, F. P., Machumi, F., Chacha, M., Cornett, Claus & Styrishave, Bjarne, 2022, In: Tropical Biomedicine. 39, 2, p. 257-264 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Cimetidine for erythropoietic protoporphyria

    Heerfordt, I. M., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 38, 5 p., 102793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Cortisol in Manure from Cattle Enclosed with Nofence Virtual Fencing

    Sonne, C., Alstrup, A. K. O., Pertoldi, C., Frikke, J., Linder, A. C. & Styrishave, Bjarne, 2022, In: Animals. 12, 21, 11 p., 3017.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Detection of cutaneous malignant melanoma using RNA sampled by tape strips: A study protocol

    Heerfordt, I. M., Andersen, Jeppe Dyrberg, Philipsen, P. A., Langhans, L., Tvedebrink, Torben, Schmidt, G., Poulsen, T., Lerche, Catharina Margrethe, Morling, Niels & Wulf, H. C., 2022, In: PLoS ONE. 17, 9 , 11 p., e0274413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Distribution of protoporphyrin IX in erythrocytes in a case of acquired erythropoietic protoporphyria

    Heerfordt, I. M., Fontenete, S., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 37, 3 p., 102629.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Follicular fluid steroid hormones and in vitro embryo development in Duroc and Landrace pigs

    Jochems, R., Gaustad, A. H., Styrishave, Bjarne, Zak, L. J., Oskam, I. C., Grindflek, E., Myromslien, F. D., Kommisrud, E. & Krogenæs, A. K., 2022, In: Theriogenology. 190, p. 15-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    High Oral Vitamin D3 Intake Does Not Protect Against UVR-induced Squamous Cell Carcinoma in Mice

    Lerche, Catharina Margrethe, Pinto, F. E., Philipsen, P. A., Bech, E. S., Jakobsen, J., Hædersdal, Merete & Wulf, H. C., 2022, In: Anticancer Research. 42, 10, p. 5083-5090

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    High oral vitamin D intake does not protect against UVR-induced squamous cell carcinoma in hairless mice

    Lerche, Catharina Margrethe, Pinto, F. E., Philipsen, P. A., Bech, E., Jakobsen, J., Hædersdal, Merete & Wulf, H. C., 2022, In: Anticancer Research. 42, 4, p. 2205-2205

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  53. Published

    In vivo dermal delivery of bleomycin with electronic pneumatic injection: drug visualization and quantification with mass spectrometry

    Bik, L., van Doorn, M., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Olesen, U. H., Hædersdal, Merete, Lerche, Catharina Margrethe & Hendel, K., 2022, In: Expert Opinion on Drug Delivery. 19, 2, p. 213-219

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 3 Next