Christian Janfelt
Christian Janfelt

Associate Professor


  1. 2019
  2. Published

    Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

    Hendel, K. K., Bagger, C., Olesen, U. H., Janfelt, Christian, Hansen, S. H., Hædersdal, Merete & Lerche, C. M., Dec 2019, In : Drug Delivery. 26, 1, p. 244-251 8 p.

    Research output: Contribution to journalJournal article

  3. Published

    Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin

    Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In : Journal of Experimental Botany. 70, 20, p. 5799-5808

    Research output: Contribution to journalJournal article

  4. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In : Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journalJournal article

  5. Published

    Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery

    Handler, Anne Mette, Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In : European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.

    Research output: Contribution to journalJournal article

  6. Published

    Characterisation and localisation of the endocannabinoid system components in the adult human testis

    Nielsen, J. E., Rolland, A. D., Rajpert-De Meyts, E., Janfelt, Christian, Jørgensen, A., Winge, S. B., Kristensen, D. M., Juul, Anders, Chalmel, F., Jégou, B. & Skakkebæk, Niels Erik, 2019, In : Scientific Reports. 9, 1, 14 p., 12866.

    Research output: Contribution to journalJournal article

  7. 2018
  8. Published

    Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice

    Morineau, L., Jacobsen, S. C., Kleberg, K., Hansen, Harald S. & Janfelt, Christian, 2 Dec 2018, In : Expert Opinion on Drug Delivery. 15, 12, p. 1157-1163

    Research output: Contribution to journalJournal article

  9. Published

    Buccal delivery of small molecules - Impact of levulinic acid, oleic acid, sodium dodecyl sulfate and hypotonicity on ex vivo permeability and spatial distribution in mucosa

    Hansen, S. E., Marxen, E., Janfelt, Christian & Jacobsen, Jette, Dec 2018, In : European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 250-257

    Research output: Contribution to journalJournal article

  10. Published

    The iP-gp cell model is an improved tool for predicting the in vivo relevance of P-gp mediated efflux at the blood-brain barrier

    Ozgür, Burak, Saaby, L., Eneberg, E., Langthaler, K., Jacobsen, A., Janfelt, Christian, Badolo, L., Montanari, D. & Brodin, Birger, 22 Jun 2018.

    Research output: Contribution to conferencePosterResearchpeer-review

  11. Published

    MALDI imaging of enzymatic degradation of glycerides by lipase on textile surface

    Granborg, Jonatan Riber, Kaasgaard, S. G. & Janfelt, Christian, Mar 2018, In : Chemistry and Physics of Lipids. 211, p. 100-106

    Research output: Contribution to journalJournal article

  12. Published

    Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging

    Marxen, E., Jin, L., Jacobsen, Jette, Janfelt, Christian, Hyrup, B. & Nicolazzo, J. A., 21 Feb 2018, In : Pharmaceutical Research. 35, 3, 12 p., 70.

    Research output: Contribution to journalJournal article

  13. Published

    Permeability Barriers for Nicotine and Mannitol in Porcine Buccal. Mucosa Studied by High-Resolution MALDI Mass Spectrometry Imaging

    Marxen, E., Jacobsen, Jette, Hyrup, B. & Janfelt, Christian, Feb 2018, In : Molecular Pharmaceutics. 15, 2, p. 519-526

    Research output: Contribution to journalJournal article

  14. Published

    The Spatial Distribution of Alkaloids in Psychotria prunifolia (Kunth) Steyerm and Palicourea coriacea (Cham.) K. Schum Leaves Analysed by Desorption Electrospray Ionisation Mass Spectrometry Imaging

    Kato, L., Moraes, A. P., de Oliveira, C. M. A., Vaz, B. G., de Almeida Gonçalves, L., E Silva, E. C. & Janfelt, Christian, 2018, In : Phytochemical Analysis. 29, p. 69-76

    Research output: Contribution to journalJournal article

  15. Published

    The intracellular localization of the vanillin biosynthetic machinery in pods of Vanilla planifolia

    Gallage, N. J., Jørgensen, Kirsten, Janfelt, Christian, Nielsen, A. J. Z., Naake, T., Dunski, E., Dalsten, Lene, Grisoni, M. & Møller, Birger Lindberg, 2018, In : Plant and Cell Physiology. 59, 2, p. 304-318 15 p.

    Research output: Contribution to journalJournal article

  16. 2017
  17. Published

    Combination of MALDI-MSI and cassette dosing for evaluation of drug distribution in human skin explant

    Sørensen, I. S., Janfelt, Christian, Nielsen, M. M. B., Mortensen, R. W., Knudsen, N. Ø., Eriksson, A. H., Pedersen, A. J. & Nielsen, K. T., Aug 2017, In : Analytical and Bioanalytical Chemistry. 409, 21, p. 4993-5005 13 p.

    Research output: Contribution to journalJournal article

  18. Published

    Fractional laser-assisted topical delivery leads to enhanced, accelerated and deeper cutaneous 5-fluorouracil uptake

    Wenande, E., Olesen, U. H., Nielsen, M. M. B., Janfelt, Christian, Hansen, S. H., Anderson, R. & Hædersdal, Merete, 2017, In : Expert Opinion on Drug Delivery. 14, 3, p. 307-317 10 p.

    Research output: Contribution to journalJournal article

  19. 2016
  20. Published

    Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia

    Nielsen, M. M. B., Lambertsen, K. L., Clausen, B. H., Meyer, M., Bhandari, D. R., Larsen, S. T., Poulsen, Steen Seier, Spengler, B., Janfelt, Christian & Hansen, Harald S., 22 Dec 2016, In : Scientific Reports. 6, p. 1-14 14 p., 39571.

    Research output: Contribution to journalJournal article

  21. Published

    Fractional laser-assisted drug delivery: Laser channel depth influences biodistribution and skin deposition of methotrexate

    Taudorf, E. H., Lerche, C. M., Erlendsson, A. M., Philipsen, P. A., Hansen, S. H., Janfelt, Christian, Paasch, U., Anderson, R. R. & Hædersdal, Merete, Jul 2016, In : Lasers in Surgery and Medicine. 48, 5, p. 519-529 11 p.

    Research output: Contribution to journalJournal article

  22. Published
  23. Published

    Aspects of Quantitation in Mass Spectrometry Imaging Investigated on Cryo-Sections of Spiked Tissue Homogenates

    Hansen, H. T. & Janfelt, Christian, 2016, In : Analytical Chemistry. 88, 23, p. 11513−11520 8 p.

    Research output: Contribution to journalJournal article

  24. Published

    Characterization of midazolam metabolism in locusts: The role of CYP3A4-like enzyme in the formation of 1'-OH and 4-OH midazolam

    Olsen, L. R., Gabel-Jensen, C., Wubshet, S. G., Kongstad, Kenneth Thermann, Janfelt, Christian, Badolo, L. & Hansen, S. H., 2016, In : Xenobiotica. 46, 2, p. 99–107 9 p.

    Research output: Contribution to journalJournal article

  25. Published

    Interspecific variation in localization of hypericins and phloroglucinols in the genus Hypericum as revealed by desorption electrospray ionization mass spectrometry imaging

    Kucharíková, A., Kimáková, K., Janfelt, Christian & Cellárová, E., 2016, In : Physiologia Plantarum. 157, 1, p. 2-12 11 p.

    Research output: Contribution to journalJournal article

  26. 2015
  27. Published

    DESI-MS imaging of metabolites in various plant materials – a matter of sample preparation

    Kato, L., Rook, F., Møller, Birger Lindberg, Hansen, S. H. & Janfelt, Christian, 2015.

    Research output: Contribution to conferencePosterResearch

  28. Published

    Distribution of terfenadine and its metabolites in locusts studied by desorption electrospray ionization mass spectrometry imaging

    Olsen, L. R., Hansen, S. H. & Janfelt, Christian, 2015, In : Analytical and Bioanalytical Chemistry. 407, 8, p. 2149–2158 10 p.

    Research output: Contribution to journalJournal article

  29. Published

    Imaging of plant materials using indirect desorption electrospray ionization mass spectrometry

    Janfelt, Christian, 2015, Mass Spectrometry Imaging of Small Molecules. He, L. (ed.). Humana Press, Vol. 1203. p. 91-7 7 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  30. Published

    Topically applied methotrexate is rapidly delivered into skin by fractional laser ablation

    Taudorf, E. H., Lerche, C., Vissing, A., Philipsen, P. A., Hannibal, J., D'Alvise, U. J. C., Hansen, S. H., Janfelt, Christian, Paasch, U., Anderson, R. R. & Hædersdal, Merete, 2015, In : Expert Opinion on Drug Delivery. 12, 7, p. 1059-1069 11 p.

    Research output: Contribution to journalJournal article

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