Christian Janfelt

Christian Janfelt

Associate Professor


  1. Published

    Visualizing metabolite distribution and enzymatic conversion in plant tissues by desorption electrospray ionization mass spectrometry imaging

    Li, B., Baden, C. K., Hansen, N. K. K., Jørgensen, Kirsten, Kannangara, R. M., Bak, Søren, Takos, A. M., Rook, F., Hansen, S. H., Møller, Birger Lindberg, Janfelt, Christian & Bjarnholt, Nanna, 2013, In : Plant Journal. 74, 6, p. 1059-1071 74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery

    Handler, Anne Mette, Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In : European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Visualization by mass spectrometry of 2-dimensional changes in rat brain lipids, including N-acylphosphatidylethanolamines, during neonatal brain ischemia

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012, In : F A S E B Journal. 26, 6, p. 2667-2673

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Topically applied methotrexate is rapidly delivered into skin by fractional laser ablation

    Taudorf, E. H., Lerche, C., Vissing, A., Philipsen, P. A., Hannibal, J., D'Alvise, U. J. C., Hansen, S. H., Janfelt, Christian, Paasch, U., Anderson, R. R. & Hædersdal, Merete, 2015, In : Expert Opinion on Drug Delivery. 12, 7, p. 1059-1069 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. The magnitude of pseudo-potential errors for density functional calculations

    Janfelt, Christian & Jensen, F., 2005, In : Chemical Physics Letters. 412, p. 501-503 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. The magnitude of pseudo-potential errors for bond distances and vibrational frequencies

    Jensen, F. & Janfelt, Christian, 2005, In : Chemical Physics Letters. 412, p. 12-15 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The intracellular localization of the vanillin biosynthetic machinery in pods of Vanilla planifolia

    Gallage, N. J., Jørgensen, Kirsten, Janfelt, Christian, Nielsen, A. J. Z., Naake, T., Dunski, E., Dalsten, Lene, Grisoni, M. & Møller, Birger Lindberg, 2018, In : Plant and Cell Physiology. 59, 2, p. 304-318 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The iP-gp cell model is an improved tool for predicting the in vivo relevance of P-gp mediated efflux at the blood-brain barrier

    Ozgür, Burak, Saaby, L., Eneberg, E., Langthaler, K., Jacobsen, A., Janfelt, Christian, Badolo, L., Montanari, D. & Brodin, Birger, 22 Jun 2018.

    Research output: Contribution to conferencePosterResearchpeer-review

  9. Published

    The Spatial Distribution of Alkaloids in Psychotria prunifolia (Kunth) Steyerm and Palicourea coriacea (Cham.) K. Schum Leaves Analysed by Desorption Electrospray Ionisation Mass Spectrometry Imaging

    Kato, L., Moraes, A. P., de Oliveira, C. M. A., Vaz, B. G., de Almeida Gonçalves, L., E Silva, E. C. & Janfelt, Christian, 2018, In : Phytochemical Analysis. 29, p. 69-76

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Studies of an insect model for drug metabolism by Desorption Electrospray Ionization Mass Spectrometry Imaging

    Olsen, L. R., Hansen, S. H. & Janfelt, Christian, Aug 2014.

    Research output: Contribution to conferencePosterResearch

  11. Published

    Release of VOCs and particles during use of nanofilm spray products

    Nørgaard, A. W., Jensen, K. A., Janfelt, Christian, Lauritsen, F. R., Clausen, P. A. & Wolkoff, P., 2009, In : Environmental Science and Technology. 43, 20, p. 7824-7830 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin

    Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In : Journal of Experimental Botany. 70, 20, p. 5799-5808

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Portable electrospray ionization mass spectrometry (ESI-MS) for analysis of contaminants in the field

    Janfelt, Christian, Græsbøll, R. & Lauritsen, F. R., 2012, In : International Journal of Environmental Analytical Chemistry. 92, 4, p. 397–404 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Permeability Barriers for Nicotine and Mannitol in Porcine Buccal. Mucosa Studied by High-Resolution MALDI Mass Spectrometry Imaging

    Marxen, E., Jacobsen, Jette, Hyrup, B. & Janfelt, Christian, Feb 2018, In : Molecular Pharmaceutics. 15, 2, p. 519-526

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    On-line monitoring of VOC emissions from nanofilm coating products using a handheld membrane inlet mass spectrometer

    Nørgaard, A. W., Janfelt, Christian, Wolkoff, P., Jensen, K. A. & Lauritsen, F. R., 2008.

    Research output: Contribution to conferencePosterResearch

  16. Published

    Nebulization ionization and desorption ionization analysis of reactive organofunctionalized silanes in nanofilm products

    Nørgaard, A. W., Janfelt, Christian, Benassi, M., Wolkoff, P. & Lauritsen, F. R., 2011, In : Journal of Mass Spectrometry. 46, 4, p. 402-410

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Natural products in Glycyrrhiza glabra (licorice) rhizome imaged at the cellular level by atmospheric pressure matrix-assisted laser desorption/ionization tandem mass spectrometry imaging

    Li, B., Bhandari, D. R., Janfelt, Christian, Römpp, A. & Spengler, B., Oct 2014, In : Plant Journal. 80, 1, p. 161-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    N-acylation of phosphatidylethanolamine and its biological functions in mammals

    Wellner, N., Diep, T. A., Janfelt, Christian & Hansen, Harald S., Mar 2013, In : BBA General Subjects. 1831, 3, p. 652-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In : Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Method for Quantification of Chemicals in a Pollution Plume Using a Moving Membrane-Based Sensor Exemplified by Mass Spectrometry

    Janfelt, Christian, Lauritsen, F. R., Toler, S. K., Bell, R. J. & Short, R. T., 2007, In : Analytical Chemistry. 79, p. 5336-5342 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv

    Janfelt, Christian, Thunig, J., Li, B., Andersen, N. W., Hansen, Harald S. & Hansen, S. H., Dec 2011, In : Lægemiddelforskning. 2011, p. 10-12

    Research output: Contribution to journalJournal articleCommunication

  22. Published

    Mass spectrometry imaging of plant metabolites – principles and possibilities

    Bjarnholt, Nanna, Li, B., D'Alvise, J. & Janfelt, Christian, 2014, In : Natural Product Reports. 31, 6, p. 818-837 20 p.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia

    Nielsen, M. M. B., Lambertsen, K. L., Clausen, B. H., Meyer, M., Bhandari, D. R., Larsen, S. T., Poulsen, Steen Seier, Spengler, B., Janfelt, Christian & Hansen, Harald S., 22 Dec 2016, In : Scientific Reports. 6, p. 1-14 14 p., 39571.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Mass spectra of proteins and other biomolecules recorded using a handheld instrument

    Janfelt, Christian, Talaty, N., Mulligan C., C., Keil, A., Quyang, Z. & Cooks, R. G., 2008, In : International Journal of Mass Spectrometry. 278, 2-3, p. 166-169

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    MALDI imaging of enzymatic degradation of glycerides by lipase on textile surface

    Granborg, Jonatan Riber, Kaasgaard, S. G. & Janfelt, Christian, Mar 2018, In : Chemistry and Physics of Lipids. 211, p. 100-106

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine

    Thunig, J., Flø, L., Pedersen-Bjergaard, Stig, Hansen, S. H. & Janfelt, Christian, 2012, In : Rapid Communications in Massspectrometry. 26, 2, p. 133-140

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Liquid-Phase MicroExtraction coupled to Desorption Electrospray Ionization Mass Spectrometry in pharmaceutical analysis

    Janfelt, Christian, Thunig, U. J. C., Pedersen-Bjergaard, Stig & Hansen, S. H., 2009.

    Research output: Contribution to conferencePosterResearch

  28. Published

    Kan analyselaboratoriet flyttes i felten?

    Janfelt, Christian & Lauritsen, F. R., 2008, In : LMFK-Bladet. 1, p. 31-34 4 p.

    Research output: Contribution to journalJournal articleCommissioned

  29. Published

    Ischemia in neonatal rat brains analyzed by Desorption Electrospray Ionization Imaging mass spectrometry

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

  30. Published
  31. Published

    Interspecific variation in localization of hypericins and phloroglucinols in the genus Hypericum as revealed by desorption electrospray ionization mass spectrometry imaging

    Kucharíková, A., Kimáková, K., Janfelt, Christian & Cellárová, E., 2016, In : Physiologia Plantarum. 157, 1, p. 2-12 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Indirect DESI imaging of secondary metabolites in plant material

    Janfelt, Christian, Thunig, U. J. C., Li, B. & Hansen, S. H., 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  33. Published

    Imaging of plant materials using indirect desorption electrospray ionization mass spectrometry

    Janfelt, Christian, 2015, Mass Spectrometry Imaging of Small Molecules. He, L. (ed.). Humana Press, Vol. 1203. p. 91-7 7 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  34. Published

    High-throughput analysis of drugs in biological fluids by desorption electrospray ionization mass spectrometry coupled with thin liquid membrane extraction

    Rosting, C., Pedersen-Bjergaard, Stig, Hansen, S. H. & Janfelt, Christian, 2013, In : Analyst. 138, 20, p. 5965-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

    Hendel, K. K., Bagger, C., Olesen, U. H., Janfelt, Christian, Hansen, S. H., Hædersdal, Merete & Lerche, C. M., Dec 2019, In : Drug Delivery. 26, 1, p. 244-251 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Fractional laser-assisted topical delivery leads to enhanced, accelerated and deeper cutaneous 5-fluorouracil uptake

    Wenande, E., Olesen, U. H., Nielsen, M. M. B., Janfelt, Christian, Hansen, S. H., Anderson, R. & Hædersdal, Merete, 2017, In : Expert Opinion on Drug Delivery. 14, 3, p. 307-317 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Fractional laser-assisted drug delivery: Laser channel depth influences biodistribution and skin deposition of methotrexate

    Taudorf, E. H., Lerche, C. M., Erlendsson, A. M., Philipsen, P. A., Hansen, S. H., Janfelt, Christian, Paasch, U., Anderson, R. R. & Hædersdal, Merete, Jul 2016, In : Lasers in Surgery and Medicine. 48, 5, p. 519-529 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Fast and direct screening of polyaromatic hydrocarbon (PAH)-contaminated sand using a miniaturized membrane inlet mass spectrometer (mini-MIMS)

    Frandsen, H., Janfelt, Christian & Lauritsen, F. R., 2007, In : Rapid Communications in Mass Spectrometry. 21, p. 1574-1578 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging

    Marxen, E., Jin, L., Jacobsen, Jette, Janfelt, Christian, Hyrup, B. & Nicolazzo, J. A., 21 Feb 2018, In : Pharmaceutical Research. 35, 3, 12 p., 70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Distribution of terfenadine and its metabolites in locusts studied by desorption electrospray ionization mass spectrometry imaging

    Olsen, L. R., Hansen, S. H. & Janfelt, Christian, 2015, In : Analytical and Bioanalytical Chemistry. 407, 8, p. 2149–2158 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Displaced dual-mode imaging with desorption electrospray ionization for simultaneous mass spectrometry imaging in both polarities and with several scan modes

    Janfelt, Christian, Wellner, N., Hansen, Harald S. & Hansen, S. H., Mar 2013, In : Journal of Mass Spectrometry. 48, 3, p. 361-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Direkte analyse med DESI-MS

    Thunig, J., Lauritsen, F. R., Hansen, S. H., Janfelt, Christian & Christophersen, C., 2010, In : Dansk Kemi. 91, 3, p. 21-23 3 p.

    Research output: Contribution to journalJournal articleResearch

  43. Published

    Direct imaging of plant metabolites in leaves and petals by Desorption Electrospray Ionization mass spectrometry

    Li, B., Hansen, S. H. & Janfelt, Christian, 2013, In : International Journal of Mass Spectrometry. 348, p. 15-22

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Direct and indirect imaging of secondary metabolites and enzymatic reactions in plant material by Desorption Electrospray Ionization

    Li, B., Bjarnholt, Nanna, Knudsen, C., D'Alvise, J., Hansen, S. H. & Janfelt, Christian, 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

  45. Published

    Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

    Christfort, J. F., Strindberg, Sophie , Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Detection of follicular transport of lidocaine and metabolism in adipose tissue in pig ear skin by DESI mass spectrometry imaging

    D'Alvise, J., Mortensen, R., Hansen, S. H. & Janfelt, Christian, Jun 2014, In : Analytical and Bioanalytical Chemistry. 406, 15, p. 3735-42 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice

    Morineau, L., Jacobsen, S. C., Kleberg, K., Hansen, Harald S. & Janfelt, Christian, 2 Dec 2018, In : Expert Opinion on Drug Delivery. 15, 12, p. 1157-1163

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    DESI-MS imaging of metabolites in various plant materials – a matter of sample preparation

    Kato, L., Rook, F., Møller, Birger Lindberg, Hansen, S. H. & Janfelt, Christian, 2015.

    Research output: Contribution to conferencePosterResearch

  49. Published

    Cryo-sectioning of mice for whole-body imaging of drugs and metabolites with desorption electrospray ionization mass spectrometry imaging - a simplified approach

    Okutan, S., Hansen, Harald S. & Janfelt, Christian, Jun 2016, In : Proteomics. 16, 11-12, p. 1633-41 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Combination of MALDI-MSI and cassette dosing for evaluation of drug distribution in human skin explant

    Sørensen, I. S., Janfelt, Christian, Nielsen, M. M. B., Mortensen, R. W., Knudsen, N. Ø., Eriksson, A. H., Pedersen, A. J. & Nielsen, K. T., Aug 2017, In : Analytical and Bioanalytical Chemistry. 409, 21, p. 4993-5005 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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