USING OXYGEN-CONSUMING THERMOSET PLASTICS TO GENERATE HYPOXIC CONDITIONS IN MICROFLUIDIC DEVICES FOR POTENTIAL CELL CULTURE APPLICATIONS
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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USING OXYGEN-CONSUMING THERMOSET PLASTICS TO GENERATE HYPOXIC CONDITIONS IN MICROFLUIDIC DEVICES FOR POTENTIAL CELL CULTURE APPLICATIONS. / Sticker, Drago; Rothbauer, Mario; Ehgartner, Josef; Steininger, Christoph ; Neuhaus, Winfried; Mayr, Torsten; Haraldsson, Tommy; Kutter, Jörg P.; Ertl, Peter.
2017. Abstract from The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017) , Savannah, United States.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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TY - ABST
T1 - USING OXYGEN-CONSUMING THERMOSET PLASTICS TO GENERATE HYPOXIC CONDITIONS IN MICROFLUIDIC DEVICES FOR POTENTIAL CELL CULTURE APPLICATIONS
AU - Sticker, Drago
AU - Rothbauer, Mario
AU - Ehgartner, Josef
AU - Steininger, Christoph
AU - Neuhaus, Winfried
AU - Mayr, Torsten
AU - Haraldsson, Tommy
AU - Kutter, Jörg P.
AU - Ertl, Peter
PY - 2017/10
Y1 - 2017/10
N2 - The precise control of the oxygen concentration in a cellular environment allows the study of cells under physiologically relevant conditions. This work reports on a novel method for the generation of reduced dissolved oxygen concentrations in microfluidic chambers for cell- and organ-on-chip applications. Using a thermoset polymeric material (OSTEMERTM), which effectively scavenges dissolved oxygen (DO), microfluidic devices have been fabricated where oxygen was rapidly depleted from the microfluidic chamber. It is shown that hypoxic and anaerobic conditions can be generated through the inherent scavenging property of the material itself, without any additional chemical additives.
AB - The precise control of the oxygen concentration in a cellular environment allows the study of cells under physiologically relevant conditions. This work reports on a novel method for the generation of reduced dissolved oxygen concentrations in microfluidic chambers for cell- and organ-on-chip applications. Using a thermoset polymeric material (OSTEMERTM), which effectively scavenges dissolved oxygen (DO), microfluidic devices have been fabricated where oxygen was rapidly depleted from the microfluidic chamber. It is shown that hypoxic and anaerobic conditions can be generated through the inherent scavenging property of the material itself, without any additional chemical additives.
UR - https://www.microtas2017.org/program/MicroTAS2017_FinalProgram.pdf
M3 - Conference abstract for conference
T2 - The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017)
Y2 - 22 October 2017 through 26 October 2017
ER -
ID: 183800213