Towards physico-relevant dissolution testing: The importance of solid-state analysis in dissolution
Research output: Contribution to journal › Comment/debate › Research › peer-review
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Towards physico-relevant dissolution testing : The importance of solid-state analysis in dissolution. / Aaltonen, Jaakko; Rades, Thomas.
In: Dissolution Technologies, Vol. 16, No. 2, 05.2009, p. 47-54.Research output: Contribution to journal › Comment/debate › Research › peer-review
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TY - JOUR
T1 - Towards physico-relevant dissolution testing
T2 - The importance of solid-state analysis in dissolution
AU - Aaltonen, Jaakko
AU - Rades, Thomas
PY - 2009/5
Y1 - 2009/5
N2 - Polymorphism and other solid-state phenomena can have effects on many physicochemical properties of pharmaceuticals. In this commentary, some aspects of solid-state pharmaceutics that are important to dissolution testing are highlighted. Examples of how solid-state analysis can be used to aid interpretation of dissolution results are also reviewed. We suggest the term physico-relevant dissolution testing to describe the combination of dissolution testing with solid-state analysis.
AB - Polymorphism and other solid-state phenomena can have effects on many physicochemical properties of pharmaceuticals. In this commentary, some aspects of solid-state pharmaceutics that are important to dissolution testing are highlighted. Examples of how solid-state analysis can be used to aid interpretation of dissolution results are also reviewed. We suggest the term physico-relevant dissolution testing to describe the combination of dissolution testing with solid-state analysis.
UR - http://www.scopus.com/inward/record.url?scp=69349100378&partnerID=8YFLogxK
U2 - 10.14227/DT160209P47
DO - 10.14227/DT160209P47
M3 - Comment/debate
AN - SCOPUS:69349100378
VL - 16
SP - 47
EP - 54
JO - Dissolution Technologies
JF - Dissolution Technologies
SN - 1521-298X
IS - 2
ER -
ID: 399070509