Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis

Research output: Contribution to journalJournal articlepeer-review

Standard

Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis. / Rømer, Maria Unni Koefoed; Nygård, Sune Boris; Christensen, Ib Jarle; Nielsen, Signe Lykke; Nielsen, Kirsten Vang; Müller, Sven; Smith, David Hersi; Vainer, Ben; Nielsen, Hans Jørgen; Brünner, Nils.

In: Molecular Oncology, Vol. 7, No. 1, 2013, p. 101-111.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Rømer, MUK, Nygård, SB, Christensen, IJ, Nielsen, SL, Nielsen, KV, Müller, S, Smith, DH, Vainer, B, Nielsen, HJ & Brünner, N 2013, 'Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis', Molecular Oncology, vol. 7, no. 1, pp. 101-111. https://doi.org/10.1016/j.molonc.2012.09.001

APA

Rømer, M. U. K., Nygård, S. B., Christensen, I. J., Nielsen, S. L., Nielsen, K. V., Müller, S., Smith, D. H., Vainer, B., Nielsen, H. J., & Brünner, N. (2013). Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis. Molecular Oncology, 7(1), 101-111. https://doi.org/10.1016/j.molonc.2012.09.001

Vancouver

Rømer MUK, Nygård SB, Christensen IJ, Nielsen SL, Nielsen KV, Müller S et al. Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis. Molecular Oncology. 2013;7(1):101-111. https://doi.org/10.1016/j.molonc.2012.09.001

Author

Rømer, Maria Unni Koefoed ; Nygård, Sune Boris ; Christensen, Ib Jarle ; Nielsen, Signe Lykke ; Nielsen, Kirsten Vang ; Müller, Sven ; Smith, David Hersi ; Vainer, Ben ; Nielsen, Hans Jørgen ; Brünner, Nils. / Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis. In: Molecular Oncology. 2013 ; Vol. 7, No. 1. pp. 101-111.

Bibtex

@article{0dcf79d4681349588f9afc9c983c4508,
title = "Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis",
abstract = "A Topoisomerase 1 (Top1) poison is frequently included in the treatment regimens for metastatic colorectal cancer (mCRC). However, no predictive biomarkers for Top1 poisons are available. We here report a study on the TOP1 gene copy number in CRC patients and its association with patient prognosis and tumor cell proliferation.",
keywords = "Former LIFE faculty, Colorectal cancer, Prognosis, FISH, Topoisomerase 1, Gene copy number, Biomarker",
author = "R{\o}mer, {Maria Unni Koefoed} and Nyg{\aa}rd, {Sune Boris} and Christensen, {Ib Jarle} and Nielsen, {Signe Lykke} and Nielsen, {Kirsten Vang} and Sven M{\"u}ller and Smith, {David Hersi} and Ben Vainer and Nielsen, {Hans J{\o}rgen} and Nils Br{\"u}nner",
note = "Copyright {\textcopyright} 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.",
year = "2013",
doi = "10.1016/j.molonc.2012.09.001",
language = "English",
volume = "7",
pages = "101--111",
journal = "Molecular Oncology",
issn = "1574-7891",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis

AU - Rømer, Maria Unni Koefoed

AU - Nygård, Sune Boris

AU - Christensen, Ib Jarle

AU - Nielsen, Signe Lykke

AU - Nielsen, Kirsten Vang

AU - Müller, Sven

AU - Smith, David Hersi

AU - Vainer, Ben

AU - Nielsen, Hans Jørgen

AU - Brünner, Nils

N1 - Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

PY - 2013

Y1 - 2013

N2 - A Topoisomerase 1 (Top1) poison is frequently included in the treatment regimens for metastatic colorectal cancer (mCRC). However, no predictive biomarkers for Top1 poisons are available. We here report a study on the TOP1 gene copy number in CRC patients and its association with patient prognosis and tumor cell proliferation.

AB - A Topoisomerase 1 (Top1) poison is frequently included in the treatment regimens for metastatic colorectal cancer (mCRC). However, no predictive biomarkers for Top1 poisons are available. We here report a study on the TOP1 gene copy number in CRC patients and its association with patient prognosis and tumor cell proliferation.

KW - Former LIFE faculty

KW - Colorectal cancer

KW - Prognosis

KW - FISH

KW - Topoisomerase 1

KW - Gene copy number

KW - Biomarker

U2 - 10.1016/j.molonc.2012.09.001

DO - 10.1016/j.molonc.2012.09.001

M3 - Journal article

C2 - 23110915

VL - 7

SP - 101

EP - 111

JO - Molecular Oncology

JF - Molecular Oncology

SN - 1574-7891

IS - 1

ER -

ID: 40707423