Recent developments in oral lipid-based drug delivery

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Recent developments in oral lipid-based drug delivery. / Thomas, N.; Rades, T.; Müllertz, A.

In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 01.07.2013, p. 375-382.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Thomas, N, Rades, T & Müllertz, A 2013, 'Recent developments in oral lipid-based drug delivery', Journal of Drug Delivery Science and Technology, vol. 23, no. 4, pp. 375-382. <http://www.scopus.com/inward/record.url?scp=84881568861&partnerID=8YFLogxK>

APA

Thomas, N., Rades, T., & Müllertz, A. (2013). Recent developments in oral lipid-based drug delivery. Journal of Drug Delivery Science and Technology, 23(4), 375-382. http://www.scopus.com/inward/record.url?scp=84881568861&partnerID=8YFLogxK

Vancouver

Thomas N, Rades T, Müllertz A. Recent developments in oral lipid-based drug delivery. Journal of Drug Delivery Science and Technology. 2013 Jul 1;23(4):375-382.

Author

Thomas, N. ; Rades, T. ; Müllertz, A. / Recent developments in oral lipid-based drug delivery. In: Journal of Drug Delivery Science and Technology. 2013 ; Vol. 23, No. 4. pp. 375-382.

Bibtex

@article{b0b548da3ea74e84a6d61c37f8f65d9b,
title = "Recent developments in oral lipid-based drug delivery",
abstract = "The increasing number of poorly water-soluble drugs in development in the pharmaceutical industry has sparked interest in novel drug delivery options such as lipid-based drug delivery systems (LbDDS). Several LbDDS have been marketed successfully and have shown superior and more reliable bioavailability compared to conventional formulations. However, some reluctance in the broader application of LbDDS still appears, despite the growing commercial interest in lipids as a drug delivery platform. This reluctance might at least in part be related to the complexity associated with the development and characterization of LbDDS. In particular, the lack of standardized test protocols can be identified as the major obstacles for the broader application of LbDDS. This review seeks to summarize recent approaches in the field of lipid-based drug delivery that try to elucidate some critical steps in their development and characterization.",
keywords = "(Super-)SNEDDS, Absorption, In vitro lipolysis, Lipids",
author = "N. Thomas and T. Rades and A. M{\"u}llertz",
year = "2013",
month = jul,
day = "1",
language = "English",
volume = "23",
pages = "375--382",
journal = "Journal of Drug Delivery Science and Technology",
issn = "1773-2247",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Recent developments in oral lipid-based drug delivery

AU - Thomas, N.

AU - Rades, T.

AU - Müllertz, A.

PY - 2013/7/1

Y1 - 2013/7/1

N2 - The increasing number of poorly water-soluble drugs in development in the pharmaceutical industry has sparked interest in novel drug delivery options such as lipid-based drug delivery systems (LbDDS). Several LbDDS have been marketed successfully and have shown superior and more reliable bioavailability compared to conventional formulations. However, some reluctance in the broader application of LbDDS still appears, despite the growing commercial interest in lipids as a drug delivery platform. This reluctance might at least in part be related to the complexity associated with the development and characterization of LbDDS. In particular, the lack of standardized test protocols can be identified as the major obstacles for the broader application of LbDDS. This review seeks to summarize recent approaches in the field of lipid-based drug delivery that try to elucidate some critical steps in their development and characterization.

AB - The increasing number of poorly water-soluble drugs in development in the pharmaceutical industry has sparked interest in novel drug delivery options such as lipid-based drug delivery systems (LbDDS). Several LbDDS have been marketed successfully and have shown superior and more reliable bioavailability compared to conventional formulations. However, some reluctance in the broader application of LbDDS still appears, despite the growing commercial interest in lipids as a drug delivery platform. This reluctance might at least in part be related to the complexity associated with the development and characterization of LbDDS. In particular, the lack of standardized test protocols can be identified as the major obstacles for the broader application of LbDDS. This review seeks to summarize recent approaches in the field of lipid-based drug delivery that try to elucidate some critical steps in their development and characterization.

KW - (Super-)SNEDDS

KW - Absorption

KW - In vitro lipolysis

KW - Lipids

M3 - Journal article

AN - SCOPUS:84881568861

VL - 23

SP - 375

EP - 382

JO - Journal of Drug Delivery Science and Technology

JF - Journal of Drug Delivery Science and Technology

SN - 1773-2247

IS - 4

ER -

ID: 120396697