Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine
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Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine. / Campbell-Tofte, Joan I A; Mølgaard, Per; Josefsen, Knud; Abdallah, Zostam; Hansen, Steen Honoré; Cornett, Claus; Mu, Huiling; Richter, Erik A.; Petersen, Henning Willads; Nørregaard, Jens Christian; Winther, Kaj.
In: Journal of Ethnopharmacology, Vol. 133, No. 2, 2011, p. 402-411.Research output: Contribution to journal › Journal article › peer-review
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T1 - Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine
AU - Campbell-Tofte, Joan I A
AU - Mølgaard, Per
AU - Josefsen, Knud
AU - Abdallah, Zostam
AU - Hansen, Steen Honoré
AU - Cornett, Claus
AU - Mu, Huiling
AU - Richter, Erik A.
AU - Petersen, Henning Willads
AU - Nørregaard, Jens Christian
AU - Winther, Kaj
N1 - CURIS 2011 5200 022
PY - 2011
Y1 - 2011
N2 - The aim of this randomized and double blinded pilot clinical trial was to investigate the anti-diabetic efficacy of the Rauvolfia-Citrus (RC) tea in humans. We have earlier shown that a combination of calorie-restriction and chronic administration of the RC tea to the genetic diabetic (BKS-db) mice resulted in the normalization of blood sugar, reduction in lipid accumulated in the mice eyes and prevention of the degeneration of the otherwise brittle BKS-db pancreas. The tea is made by boiling foliage of Rauvolfia vomitoria and fruits of Citrus aurantium and is used to treat diabetes in Nigerian folk medicine.
AB - The aim of this randomized and double blinded pilot clinical trial was to investigate the anti-diabetic efficacy of the Rauvolfia-Citrus (RC) tea in humans. We have earlier shown that a combination of calorie-restriction and chronic administration of the RC tea to the genetic diabetic (BKS-db) mice resulted in the normalization of blood sugar, reduction in lipid accumulated in the mice eyes and prevention of the degeneration of the otherwise brittle BKS-db pancreas. The tea is made by boiling foliage of Rauvolfia vomitoria and fruits of Citrus aurantium and is used to treat diabetes in Nigerian folk medicine.
U2 - 10.1016/j.jep.2010.10.013
DO - 10.1016/j.jep.2010.10.013
M3 - Journal article
C2 - 20955771
VL - 133
SP - 402
EP - 411
JO - Journal of Ethnopharmacology
JF - Journal of Ethnopharmacology
SN - 0378-8741
IS - 2
ER -
ID: 32927923