Preparing and evaluating delivery systems for proteins

Research output: Contribution to journalReviewResearchpeer-review

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Preparing and evaluating delivery systems for proteins. / Jorgensen, L; Moeller, E H; van de Weert, M; Nielsen, H M; Frokjaer, S.

In: European Journal of Pharmaceutical Sciences, Vol. 29, No. 3-4, 2006, p. 174-82.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Jorgensen, L, Moeller, EH, van de Weert, M, Nielsen, HM & Frokjaer, S 2006, 'Preparing and evaluating delivery systems for proteins', European Journal of Pharmaceutical Sciences, vol. 29, no. 3-4, pp. 174-82. https://doi.org/10.1016/j.ejps.2006.05.008

APA

Jorgensen, L., Moeller, E. H., van de Weert, M., Nielsen, H. M., & Frokjaer, S. (2006). Preparing and evaluating delivery systems for proteins. European Journal of Pharmaceutical Sciences, 29(3-4), 174-82. https://doi.org/10.1016/j.ejps.2006.05.008

Vancouver

Jorgensen L, Moeller EH, van de Weert M, Nielsen HM, Frokjaer S. Preparing and evaluating delivery systems for proteins. European Journal of Pharmaceutical Sciences. 2006;29(3-4):174-82. https://doi.org/10.1016/j.ejps.2006.05.008

Author

Jorgensen, L ; Moeller, E H ; van de Weert, M ; Nielsen, H M ; Frokjaer, S. / Preparing and evaluating delivery systems for proteins. In: European Journal of Pharmaceutical Sciences. 2006 ; Vol. 29, No. 3-4. pp. 174-82.

Bibtex

@article{3a8e0f3e6b95438ba9005720adfc83cf,
title = "Preparing and evaluating delivery systems for proteins",
abstract = "From a formulation perspective proteins are complex and therefore challenging molecules to develop drug delivery systems for. The success of a formulation depends on the ability of the protein to maintain the native structure and activity during preparation and delivery as well as during shipping and long-term storage of the formulation. Therefore, the development and evaluation of successful and promising drug delivery systems is essential. In the present review, some of the particulate drug delivery systems for parenteral delivery of protein are presented and discussed. The challenge for incorporation of protein in particulate delivery systems is exemplified by water-in-oil emulsions.",
keywords = "Calorimetry, Differential Scanning, Drug Delivery Systems, Emulsions, Hydrogels, Liposomes, Microspheres, Nanoparticles, Proteins",
author = "L Jorgensen and Moeller, {E H} and {van de Weert}, M and Nielsen, {H M} and S Frokjaer",
year = "2006",
doi = "10.1016/j.ejps.2006.05.008",
language = "English",
volume = "29",
pages = "174--82",
journal = "European Journal of Pharmaceutical Sciences",
issn = "0928-0987",
publisher = "Elsevier",
number = "3-4",

}

RIS

TY - JOUR

T1 - Preparing and evaluating delivery systems for proteins

AU - Jorgensen, L

AU - Moeller, E H

AU - van de Weert, M

AU - Nielsen, H M

AU - Frokjaer, S

PY - 2006

Y1 - 2006

N2 - From a formulation perspective proteins are complex and therefore challenging molecules to develop drug delivery systems for. The success of a formulation depends on the ability of the protein to maintain the native structure and activity during preparation and delivery as well as during shipping and long-term storage of the formulation. Therefore, the development and evaluation of successful and promising drug delivery systems is essential. In the present review, some of the particulate drug delivery systems for parenteral delivery of protein are presented and discussed. The challenge for incorporation of protein in particulate delivery systems is exemplified by water-in-oil emulsions.

AB - From a formulation perspective proteins are complex and therefore challenging molecules to develop drug delivery systems for. The success of a formulation depends on the ability of the protein to maintain the native structure and activity during preparation and delivery as well as during shipping and long-term storage of the formulation. Therefore, the development and evaluation of successful and promising drug delivery systems is essential. In the present review, some of the particulate drug delivery systems for parenteral delivery of protein are presented and discussed. The challenge for incorporation of protein in particulate delivery systems is exemplified by water-in-oil emulsions.

KW - Calorimetry, Differential Scanning

KW - Drug Delivery Systems

KW - Emulsions

KW - Hydrogels

KW - Liposomes

KW - Microspheres

KW - Nanoparticles

KW - Proteins

U2 - 10.1016/j.ejps.2006.05.008

DO - 10.1016/j.ejps.2006.05.008

M3 - Review

C2 - 16828267

VL - 29

SP - 174

EP - 182

JO - European Journal of Pharmaceutical Sciences

JF - European Journal of Pharmaceutical Sciences

SN - 0928-0987

IS - 3-4

ER -

ID: 44244172