Photocatalytic nanoparticles: From membrane interactions to antimicrobial and antiviral effects

Research output: Contribution to journalJournal articlepeer-review

Documents

  • Fulltext

    Final published version, 4.62 MB, PDF document

As a result of increasing resistance among pathogens against antibiotics and anti-viral therapeutics, nanomaterials are attracting current interest as antimicrobial agents. Such materials offer triggered functionalities to combat challenging infections, based on either direct membrane action, effects of released ions, thermal shock induced by either light or magnetic fields, or oxidative photocatalysis. In the present overview, we focus on photocatalytic antimicrobial effects, in which light exposure triggers generation of reactive oxygen species. These, in turn, cause oxidative damage to key components in bacteria and viruses, including lipid membranes, lipopolysaccharides, proteins, and DNA/RNA. While an increasing body of studies demonstrate that potent antimicrobial effects can be achieved by photocatalytic nanomaterials, understanding of the mechanistic foundation underlying such effects is still in its infancy. Addressing this, we here provide an overview of the current understanding of the interaction of photocatalytic nanomaterials with pathogen membranes and membrane components, and how this translates into antibacterial and antiviral effects.

Original languageEnglish
Article number102526
JournalAdvances in Colloid and Interface Science
Volume299
ISSN0001-8686
DOIs
Publication statusPublished - 2022

Bibliographical note

Publisher Copyright:
© 2021 The Author(s)

    Research areas

  • Antibacterial, Antimicrobial, Antiviral, Membrane, Nanoparticle, Photocatalytic, Reactive oxygen species

Number of downloads are based on statistics from Google Scholar and www.ku.dk


No data available

ID: 283015256