Necessity of rethinking oral pediatric formulations

Research output: Contribution to journalJournal articleResearchpeer-review

This commentary reviews the difficulties in formulating oral products for children. The significance of the fragmentation of the pediatric population in terms of development and ability to ingest different dosage formulations is examined. It is postulated that a flexible formulation, acceptable by all patient groups, is needed, and an automated compounding concept is proposed. The finishing of the formulation is done at the dispensing pharmacy using an automated process. The individual components (pudding-like carrier, microencapsulated drug, and the dispensing robot and its software) are reviewed. The involvement of different stakeholders is considered because new regulatory, clinical, and marketing thinking is required.

Original languageEnglish
JournalClinical Therapeutics
Volume36
Issue number2
Pages (from-to)180-3
Number of pages4
ISSN0149-2918
DOIs
Publication statusPublished - 1 Feb 2014

ID: 120792817