Intracellular calcium modulates basolateral K(+)-permeability in frog skin epithelium
Research output: Contribution to journal › Journal article › peer-review
Cytosolic calcium ([Ca2+]i) has been suggested as a key modulator in the regulation of active sodium transport across electrically "tight" (high resistance) epithelia. In this study we investigated the effects of calcium on cellular electrophysiological parameters in a classical model tissue, the frog skin. [Ca2+]i was measured with fura-2 in an epifluorescence microscope setup. An inhibition of basolateral potassium permeability was observed when cytosolic calcium was increased. This inhibition was reversible upon removal of calcium from the serosal solution.
Original language | English |
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Journal | Pflügers Archiv - European Journal of Physiology |
Volume | 426 |
Issue number | 1-2 |
Pages (from-to) | 171-3 |
Number of pages | 3 |
ISSN | 0031-6768 |
Publication status | Published - 1994 |
- Animals, Calcium, Cytosol, Epithelium, Indomethacin, Intracellular Fluid, Ion Transport, Membrane Potentials, Permeability, Potassium, Rana temporaria, Skin
Research areas
ID: 37899892