Intracellular calcium modulates basolateral K(+)-permeability in frog skin epithelium
Research output: Contribution to journal › Journal article › peer-review
Cytosolic calcium ([Ca2+]i) has been suggested as a key modulator in the regulation of active sodium transport across electrically "tight" (high resistance) epithelia. In this study we investigated the effects of calcium on cellular electrophysiological parameters in a classical model tissue, the frog skin. [Ca2+]i was measured with fura-2 in an epifluorescence microscope setup. An inhibition of basolateral potassium permeability was observed when cytosolic calcium was increased. This inhibition was reversible upon removal of calcium from the serosal solution.
|Journal||Pflügers Archiv - European Journal of Physiology|
|Number of pages||3|
|Publication status||Published - 1994|
- Animals, Calcium, Cytosol, Epithelium, Indomethacin, Intracellular Fluid, Ion Transport, Membrane Potentials, Permeability, Potassium, Rana temporaria, Skin