Intracellular calcium modulates basolateral K(+)-permeability in frog skin epithelium

Research output: Contribution to journalJournal articleResearchpeer-review

Cytosolic calcium ([Ca2+]i) has been suggested as a key modulator in the regulation of active sodium transport across electrically "tight" (high resistance) epithelia. In this study we investigated the effects of calcium on cellular electrophysiological parameters in a classical model tissue, the frog skin. [Ca2+]i was measured with fura-2 in an epifluorescence microscope setup. An inhibition of basolateral potassium permeability was observed when cytosolic calcium was increased. This inhibition was reversible upon removal of calcium from the serosal solution.
Original languageEnglish
JournalPflügers Archiv - European Journal of Physiology
Issue number1-2
Pages (from-to)171-3
Number of pages3
Publication statusPublished - 1994

    Research areas

  • Animals, Calcium, Cytosol, Epithelium, Indomethacin, Intracellular Fluid, Ion Transport, Membrane Potentials, Permeability, Potassium, Rana temporaria, Skin

ID: 37899892