Innovative Methods and Applications in Mucoadhesion Research

Research output: Contribution to journalReviewResearchpeer-review

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Innovative Methods and Applications in Mucoadhesion Research. / Mackie, Alan R; Goycoolea, Francisco M; Menchicchi, Bianca; Caramella, Carla Marcella; Saporito, Francesca; Lee, Seunghwan; Stephansen, Karen; Chronakis, Ioannis S; Hiorth, Marianne; Adamczak, Malgorzata; Waldner, Max; Nielsen, Hanne Mørck; Marcelloni, Luciano.

In: Macromolecular Bioscience, Vol. 17, No. 8, 1600534, 08.2017.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Mackie, AR, Goycoolea, FM, Menchicchi, B, Caramella, CM, Saporito, F, Lee, S, Stephansen, K, Chronakis, IS, Hiorth, M, Adamczak, M, Waldner, M, Nielsen, HM & Marcelloni, L 2017, 'Innovative Methods and Applications in Mucoadhesion Research', Macromolecular Bioscience, vol. 17, no. 8, 1600534. https://doi.org/10.1002/mabi.201600534

APA

Mackie, A. R., Goycoolea, F. M., Menchicchi, B., Caramella, C. M., Saporito, F., Lee, S., ... Marcelloni, L. (2017). Innovative Methods and Applications in Mucoadhesion Research. Macromolecular Bioscience, 17(8), [1600534]. https://doi.org/10.1002/mabi.201600534

Vancouver

Mackie AR, Goycoolea FM, Menchicchi B, Caramella CM, Saporito F, Lee S et al. Innovative Methods and Applications in Mucoadhesion Research. Macromolecular Bioscience. 2017 Aug;17(8). 1600534. https://doi.org/10.1002/mabi.201600534

Author

Mackie, Alan R ; Goycoolea, Francisco M ; Menchicchi, Bianca ; Caramella, Carla Marcella ; Saporito, Francesca ; Lee, Seunghwan ; Stephansen, Karen ; Chronakis, Ioannis S ; Hiorth, Marianne ; Adamczak, Malgorzata ; Waldner, Max ; Nielsen, Hanne Mørck ; Marcelloni, Luciano. / Innovative Methods and Applications in Mucoadhesion Research. In: Macromolecular Bioscience. 2017 ; Vol. 17, No. 8.

Bibtex

@article{bfe9ab6b814d48298846221eb4b47380,
title = "Innovative Methods and Applications in Mucoadhesion Research",
abstract = "The present review is aimed at elucidating relatively new aspects of mucoadhesion/mucus interaction and related phenomena that emerged from a Mucoadhesion workshop held in Munster on 2-3 September 2015 as a satellite event of the ICCC 13th-EUCHIS 12th. After a brief outline of the new issues, the focus is on mucus description, purification, and mucus/mucin characterization, all steps that are pivotal to the understanding of mucus related phenomena and the choice of the correct mucosal model for in vitro and ex vivo experiments, alternative bio/mucomimetic materials are also presented. Then a selection of preparative techniques and testing methods are described (at molecular as well as micro and macroscale) that may support the pharmaceutical development of mucus interactive systems and assist formulators in the scale-up and industrialization steps. Recent applications of mucoadhesive systems (including medical devices) intended for different routes of administration (oral, gastrointestinal, vaginal, nasal, ocular, and intravesical) and for the treatment of difficult to treat pathologies or the alleviation of symptoms are described.",
keywords = "Journal Article, Review",
author = "Mackie, {Alan R} and Goycoolea, {Francisco M} and Bianca Menchicchi and Caramella, {Carla Marcella} and Francesca Saporito and Seunghwan Lee and Karen Stephansen and Chronakis, {Ioannis S} and Marianne Hiorth and Malgorzata Adamczak and Max Waldner and Nielsen, {Hanne M{\o}rck} and Luciano Marcelloni",
note = "{\circledC} 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2017",
month = "8",
doi = "10.1002/mabi.201600534",
language = "English",
volume = "17",
journal = "Macromolecular Bioscience",
issn = "1616-5187",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "8",

}

RIS

TY - JOUR

T1 - Innovative Methods and Applications in Mucoadhesion Research

AU - Mackie, Alan R

AU - Goycoolea, Francisco M

AU - Menchicchi, Bianca

AU - Caramella, Carla Marcella

AU - Saporito, Francesca

AU - Lee, Seunghwan

AU - Stephansen, Karen

AU - Chronakis, Ioannis S

AU - Hiorth, Marianne

AU - Adamczak, Malgorzata

AU - Waldner, Max

AU - Nielsen, Hanne Mørck

AU - Marcelloni, Luciano

N1 - © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

PY - 2017/8

Y1 - 2017/8

N2 - The present review is aimed at elucidating relatively new aspects of mucoadhesion/mucus interaction and related phenomena that emerged from a Mucoadhesion workshop held in Munster on 2-3 September 2015 as a satellite event of the ICCC 13th-EUCHIS 12th. After a brief outline of the new issues, the focus is on mucus description, purification, and mucus/mucin characterization, all steps that are pivotal to the understanding of mucus related phenomena and the choice of the correct mucosal model for in vitro and ex vivo experiments, alternative bio/mucomimetic materials are also presented. Then a selection of preparative techniques and testing methods are described (at molecular as well as micro and macroscale) that may support the pharmaceutical development of mucus interactive systems and assist formulators in the scale-up and industrialization steps. Recent applications of mucoadhesive systems (including medical devices) intended for different routes of administration (oral, gastrointestinal, vaginal, nasal, ocular, and intravesical) and for the treatment of difficult to treat pathologies or the alleviation of symptoms are described.

AB - The present review is aimed at elucidating relatively new aspects of mucoadhesion/mucus interaction and related phenomena that emerged from a Mucoadhesion workshop held in Munster on 2-3 September 2015 as a satellite event of the ICCC 13th-EUCHIS 12th. After a brief outline of the new issues, the focus is on mucus description, purification, and mucus/mucin characterization, all steps that are pivotal to the understanding of mucus related phenomena and the choice of the correct mucosal model for in vitro and ex vivo experiments, alternative bio/mucomimetic materials are also presented. Then a selection of preparative techniques and testing methods are described (at molecular as well as micro and macroscale) that may support the pharmaceutical development of mucus interactive systems and assist formulators in the scale-up and industrialization steps. Recent applications of mucoadhesive systems (including medical devices) intended for different routes of administration (oral, gastrointestinal, vaginal, nasal, ocular, and intravesical) and for the treatment of difficult to treat pathologies or the alleviation of symptoms are described.

KW - Journal Article

KW - Review

U2 - 10.1002/mabi.201600534

DO - 10.1002/mabi.201600534

M3 - Review

VL - 17

JO - Macromolecular Bioscience

T2 - Macromolecular Bioscience

JF - Macromolecular Bioscience

SN - 1616-5187

IS - 8

M1 - 1600534

ER -

ID: 185406676