TY - JOUR

T1 - Facial contact dermatitis caused by cosmetic-relevant allergens

AU - Bruusgaard-Mouritsen, Maria A.

AU - Garvey, Lene H.

AU - Johansen, Jeanne D.

PY - 2021

Y1 - 2021

N2 - BackgroundFacial allergic contact dermatitis caused by cosmetic products is common. New allergens in cosmetics continuously emerge.ObjectivesTo investigate characteristics of patients with facial dermatitis (FD) between 2010 and 2019 including patch test results from cosmetic-related allergens and a new test series with cosmetic-relevant natural ingredients (CRNIs).MethodsThis is a retrospective study analysing demographics, clinical characteristics according to MOAHLFA index (male; occupation; atopic dermatitis; hand; leg; face; age ≥ 40 years), and patch test results to 27 cosmetic-relevant allergens in FD patients. A prospective study evaluating a screening test series with CRNIs in consecutive FD patients for 1 year was also conducted. These patients received a questionnaire for collecting extra characteristics (eg, concerning quality of life).ResultsOf 8740 tested patients, 2292 (26.2%) had FD. Of these, 30.6% had cosmetic-induced FD. The most common cosmetic-related allergens were fragrances and preservatives. The most common patch test-positive CRNIs were hydroperoxides of limonene and linalool, and propolis. Potato and peanut were rare, but the most common prick test-positive CRNIs, however, without any relation to the use of cosmetic products. FD affected nearly all patients' quality of life and caused limitations to their daily life.ConclusionsUpdated management and quick diagnosis of FD is important to avoid negative impact on patients' quality of life.

AB - BackgroundFacial allergic contact dermatitis caused by cosmetic products is common. New allergens in cosmetics continuously emerge.ObjectivesTo investigate characteristics of patients with facial dermatitis (FD) between 2010 and 2019 including patch test results from cosmetic-related allergens and a new test series with cosmetic-relevant natural ingredients (CRNIs).MethodsThis is a retrospective study analysing demographics, clinical characteristics according to MOAHLFA index (male; occupation; atopic dermatitis; hand; leg; face; age ≥ 40 years), and patch test results to 27 cosmetic-relevant allergens in FD patients. A prospective study evaluating a screening test series with CRNIs in consecutive FD patients for 1 year was also conducted. These patients received a questionnaire for collecting extra characteristics (eg, concerning quality of life).ResultsOf 8740 tested patients, 2292 (26.2%) had FD. Of these, 30.6% had cosmetic-induced FD. The most common cosmetic-related allergens were fragrances and preservatives. The most common patch test-positive CRNIs were hydroperoxides of limonene and linalool, and propolis. Potato and peanut were rare, but the most common prick test-positive CRNIs, however, without any relation to the use of cosmetic products. FD affected nearly all patients' quality of life and caused limitations to their daily life.ConclusionsUpdated management and quick diagnosis of FD is important to avoid negative impact on patients' quality of life.

KW - Faculty of Social Sciences

KW - cosmetic products

KW - Facial dermatitis

KW - natural ingredients

KW - patch test

KW - skin prick test

U2 - 10.1111/cod.13966

DO - 10.1111/cod.13966

M3 - Journal article

C2 - 34482547

VL - 85

SP - 650

EP - 659

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 6

ER -