Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

Research output: Contribution to journalComment/debate

Standard

Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601. / Kapp, Sebastian J; Larsson, Iben; Van De Weert, Marco; Ćardenas, Marité; Jorgensen, Lene.

In: Journal of Pharmaceutical Sciences, Vol. 104, No. 10, 2015, p. 3587.

Research output: Contribution to journalComment/debate

Harvard

Kapp, SJ, Larsson, I, Van De Weert, M, Ćardenas, M & Jorgensen, L 2015, 'Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601', Journal of Pharmaceutical Sciences, vol. 104, no. 10, pp. 3587. https://doi.org/10.1002/jps.24542

APA

Kapp, S. J., Larsson, I., Van De Weert, M., Ćardenas, M., & Jorgensen, L. (2015). Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601. Journal of Pharmaceutical Sciences, 104(10), 3587. https://doi.org/10.1002/jps.24542

Vancouver

Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601. Journal of Pharmaceutical Sciences. 2015;104(10):3587. https://doi.org/10.1002/jps.24542

Author

Kapp, Sebastian J ; Larsson, Iben ; Van De Weert, Marco ; Ćardenas, Marité ; Jorgensen, Lene. / Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601. In: Journal of Pharmaceutical Sciences. 2015 ; Vol. 104, No. 10. pp. 3587.

Bibtex

@article{f542ff2719c340018b66771abe7076e6,
title = "Erratum: Kapp SJ, Larsson I, Van De Weert M, {\'C}ardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601",
abstract = "In the original version of this article, there is an error in the Early Event in Competition Studies section on page 598. The correct text is given below.An intuitive approach to explain this is by the different diffusion coefficients of PS80 (1.8 × 10− 6 cm2/s for the monomer, 1.8 × 10− 7 cm2/s for the micelle)1 and IgG1 (~ 4 × 10− 7 cm2/s).2., 3. The diffusion coefficient of the mAb and the PS80 monomer (the competing species), differ by only a factor ~ 4. Hence, there could be a limited degree of competition for the surface in the initial phase, where a fraction of the mAb would adsorb and be resistant to PS80, while another but smaller fraction initially adsorbs and is then removed by the surfactant due to insufficient contact points. However, the time scale of the event (in terms of height and width of the spike) remained constant regardless of surfactant concentrations being below or above CMC (Supplementary Figure 5), which would argue against this explanation. This same observation negates a potential transient PS80 depletion from the bulk in the early adsorption phase as a result of adsorption to tubing, since also in that case the height and width should be reduced upon increasing PS80 concentration.",
author = "Kapp, {Sebastian J} and Iben Larsson and {Van De Weert}, Marco and Marit{\'e} {\'C}ardenas and Lene Jorgensen",
note = "Refers to Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces Journal of Pharmaceutical Sciences, Volume 104, Issue 2, February 2015, Pages 593-601 Sebastian J. Kapp, Iben Larsson, Marco Van De Weert, Marit{\'e} C{\'a}rdenas, Lene Jorgensen",
year = "2015",
doi = "10.1002/jps.24542",
language = "English",
volume = "104",
pages = "3587",
journal = "Journal of Pharmaceutical Sciences",
issn = "0022-3549",
publisher = "Elsevier",
number = "10",

}

RIS

TY - JOUR

T1 - Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

AU - Kapp, Sebastian J

AU - Larsson, Iben

AU - Van De Weert, Marco

AU - Ćardenas, Marité

AU - Jorgensen, Lene

N1 - Refers to Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces Journal of Pharmaceutical Sciences, Volume 104, Issue 2, February 2015, Pages 593-601 Sebastian J. Kapp, Iben Larsson, Marco Van De Weert, Marité Cárdenas, Lene Jorgensen

PY - 2015

Y1 - 2015

N2 - In the original version of this article, there is an error in the Early Event in Competition Studies section on page 598. The correct text is given below.An intuitive approach to explain this is by the different diffusion coefficients of PS80 (1.8 × 10− 6 cm2/s for the monomer, 1.8 × 10− 7 cm2/s for the micelle)1 and IgG1 (~ 4 × 10− 7 cm2/s).2., 3. The diffusion coefficient of the mAb and the PS80 monomer (the competing species), differ by only a factor ~ 4. Hence, there could be a limited degree of competition for the surface in the initial phase, where a fraction of the mAb would adsorb and be resistant to PS80, while another but smaller fraction initially adsorbs and is then removed by the surfactant due to insufficient contact points. However, the time scale of the event (in terms of height and width of the spike) remained constant regardless of surfactant concentrations being below or above CMC (Supplementary Figure 5), which would argue against this explanation. This same observation negates a potential transient PS80 depletion from the bulk in the early adsorption phase as a result of adsorption to tubing, since also in that case the height and width should be reduced upon increasing PS80 concentration.

AB - In the original version of this article, there is an error in the Early Event in Competition Studies section on page 598. The correct text is given below.An intuitive approach to explain this is by the different diffusion coefficients of PS80 (1.8 × 10− 6 cm2/s for the monomer, 1.8 × 10− 7 cm2/s for the micelle)1 and IgG1 (~ 4 × 10− 7 cm2/s).2., 3. The diffusion coefficient of the mAb and the PS80 monomer (the competing species), differ by only a factor ~ 4. Hence, there could be a limited degree of competition for the surface in the initial phase, where a fraction of the mAb would adsorb and be resistant to PS80, while another but smaller fraction initially adsorbs and is then removed by the surfactant due to insufficient contact points. However, the time scale of the event (in terms of height and width of the spike) remained constant regardless of surfactant concentrations being below or above CMC (Supplementary Figure 5), which would argue against this explanation. This same observation negates a potential transient PS80 depletion from the bulk in the early adsorption phase as a result of adsorption to tubing, since also in that case the height and width should be reduced upon increasing PS80 concentration.

U2 - 10.1002/jps.24542

DO - 10.1002/jps.24542

M3 - Comment/debate

C2 - 26353116

VL - 104

SP - 3587

JO - Journal of Pharmaceutical Sciences

JF - Journal of Pharmaceutical Sciences

SN - 0022-3549

IS - 10

ER -

ID: 161622410