Electromembrane extraction – Recent trends and where to go

Research output: Contribution to journalReviewResearchpeer-review

Documents

Stig Pedersen-Bjergaard, Chuixiu Huang, Astrid Gjelstad

Electromembrane extraction (EME) is an analytical microextraction technique, where charged analytes (such as drug substances) are extracted from an aqueous sample (such as a biological fluid), through a supported liquid membrane (SLM) comprising a water immiscible organic solvent, and into an aqueous acceptor solution. The driving force for the extraction is an electrical potential (dc) applied across the SLM. In this paper, EME is reviewed. First, the principle for EME is explained with focus on extraction of cationic and anionic analytes, and typical performance data are presented. Second, papers published in 2016 are reviewed and discussed with focus on (a) new SLMs, (b) new support materials for the SLM, (c) new sample additives improving extraction, (d) new technical configurations, (e) improved theoretical understanding, and (f) pharmaceutical new applications. Finally, important future research objectives and directions are defined for further development of EME, with the aim of establishing EME in the toolbox of future analytical laboratories.
Original languageEnglish
JournalJournal of Pharmaceutical Analysis
Volume7
Issue number3
Pages (from-to)141-147
Number of pages7
ISSN2095-1779
DOIs
Publication statusPublished - 2017

Number of downloads are based on statistics from Google Scholar and www.ku.dk


No data available

ID: 179665029