Sven Frøkjær

Sven Frøkjær

Professor, emeritus

Member of:

    ORCID: 0000-0002-6621-3784

    Publication year:
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    1 - 50 out of 89Page size: 50
    1. 2022
    2. Published

      Guidance for pediatric use in prescription information for novel medicinal products in the EU and the US

      Christiansen, H., De Bruin, M. L., Frøkjær, Sven & Hallgreen, Christine Erikstrup, 2022, In: PLoS ONE. 17, 4, 19 p., e0266353.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2020
    4. Published

      Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing

      Öblom, H., Cornett, Claus, Bøtker, Johan Peter, Frøkjær, Sven, Hansen, Harald S., Rades, Thomas, Rantanen, Jukka & Genina, Natalja, 2020, In: International Journal of Pharmaceutics. 589, p. 1-11 119866.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. 2019
    6. Published

      Danish Physicians’ Views on the Appropriateness of the Involvement of Patients with Type 2 Diabetes in Regulatory Decision Making: A Qualitative Study

      Sachs, M. L., Colding-Jørgensen, M., Helboe, P., Kälvemark Sporrong, Sofia, Frøkjær, Sven, Jelic, K. & Kaae, Susanne, 2019, In: Pharmaceutical Medicine. 33, 2, p. 99-107

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. 2017
    8. Published

      Risk Perceptions in Diabetic Patients Who Have Experienced Adverse Events: Implications for Patient Involvement in Regulatory Decisions

      Sachs, M. L., Kälvemark Sporrong, Sofia, Colding-Jørgensen, M., Frøkjær, Sven, Helboe, P., Jelic, K. & Kaae, Susanne, 2017, In: Pharmaceutical Medicine. 31, 4, p. 245-255 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 2015
    10. Published

      Den danske kodeks for integritet i forskning

      Pedersen, H. M., Frøkjær, Sven, Bach, L. W., Vestergaard, E., Pedersen, C. V., Dirckinck-Holmfeld, L., Wegener, H. C., Jensen, L., Staunstrup, J. & Hansen, J. M., 2015

      Research output: Book/Report › Report › Communication

    11. 2013
    12. Published

      Medicon Valley - dansk-svensk succes

      Jørgensen, S., Ahren, B., Jensen, I. S. & Frøkjær, Sven, 14 Mar 2013, In: Morgenavisen Jyllands-Posten. p. 28

      Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication

    13. Published

      Biologiske lægemidler - fra molekyle til medicin

      Nielsen, Hanne Mørck, Foged, Camilla, Jørgensen, Lene & Frøkjær, Sven, 2013, In: Lægemiddelforskning. p. 12-14

      Research output: Contribution to journal › Journal article › Research

    14. Published

      Influence of acylation on the adsorption of GLP-2 to hydrophobic surfaces

      Pinholt, C., Kapp, S. J., Bukrinsky, J. T., Hostrup, S., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2013, In: International Journal of Pharmaceutics. 440, 1, p. 63-71 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. 2012
    16. Published

      Calcipotriol delivery into the skin with PEGylated liposomes

      Knudsen, N. Ø., Rønholt, Stine, Salte, R. D., Jørgensen, Lene, Thormann, T., Basse, L. H., Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 3, p. 532-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor

      Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: International Journal of Pharmaceutics. 428, 1-2, p. 171-177

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. 2011
    19. Published

      Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces

      Pinholt, C., Bukrinsky, J. T., Hostrup, S., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 139-147

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Influence of acylation on the adsorption of insulin to hydrophobic surfaces

      Pinholt, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven & Jørgensen, Lene, 2011, In: Pharmaceutical Research. 28, p. 1031-1040

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Ionic strength-dependent denaturation of Thermomyces lanuginosus lipase induced by SDS

      Fanø, M., van de Weert, Marco, Møller, E. H., Kruse, N. A. & Frøkjær, Sven, 2011, In: Archives of Biochemistry and Biophysics. 506, 1, p. 92-98

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity

      Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, p. 478-485

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. 2010
    24. Published

      Influence of glycosylation on the adsorption of Thermomyces lannuginosus lipase to hydrophobic and hydrophilic surfaces

      Pinholt, C., Fanø, M., Wiberg, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2010, In: European Journal of Pharmaceutical Sciences. 40, 4, p. 273-281

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Issues in Development of Biodrug Delivery Systems

      Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. Morishita, M. & Park, K. (eds.). 1 ed. Informa Healthcare, p. 13-25

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    26. Published

      Issues in development of biodrug delivery systems

      Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug delivery systems: fundamentals, applications and clinical development. Morishita, M. & Park, K. (eds.). New York: Informa Healthcare, p. 13-25

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    27. Published

      Penetration of gel and liquid state liposomes into barrier-impaired skin

      Knudsen, N. Ø., Frøkjær, Sven, Hansen, J., Jørgensen, Lene & Foged, Camilla, 2010, In: Journal of Pharmacy and Pharmacology. p. 793

      Research output: Contribution to journal › Conference article › Research › peer-review

    28. Published

      Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery

      Cun, D., Foged, Camilla, Yang, Mingshi, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 70-75

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation

      Jensen, D. M. K., Cun, D., Maltesen, M. J., Frøkjær, Sven, Nielsen, Hanne Mørck & Foged, Camilla, 2010, In: Journal of Controlled Release. 142, p. 138-145

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. 2009
    31. Published

      Biotechnology-based pharmaceuticals

      Jørgensen, Lene, Nielsen, Hanne Mørck & Frøkjær, Sven, 2009, Modern pharmaceutics: applications and advances. Florence, A. T. & Siepmann, J. (eds.). 5 ed. New York: Informa Healthcare, Vol. 2. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    32. Published

      Formation mechanism of insulin fibrils and structural aspects of the insulin fibrillation process

      Jensen, M. G., Frøkjær, Sven & Vestergaard, Bente, 2009, In: Current Protein and Peptide Science. 10, 5, p. 509-528

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Novel formulation approaches for peptide and protein injectables

      Yang, Mingshi & Frøkjær, Sven, 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Wiley, p. 11-28

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    34. 2008
    35. Published

      Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides

      Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Cloning of the pig PEPT2 (pPEPT2) and characterization of the effects of epidermal growth factor (EGF) on pPEPT2-mediated peptide uptake in the renal porcine cell line LLC-PK1

      Søndergaard, H. B., Bravo, S. A., Nielsen, C. U., Frøkjær, Sven & Larsen, Birger Brodin, 2008, In: European Journal of Pharmaceutical Sciences. 33, 4-5, p. 332-342

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Metode til screening af modificerede proteinlægemidler under opbevaring

      Petersen, C., Jørgensen, Lene, Hostrup, S., Bukrinsky, J. T. & Frøkjær, Sven, 2008, In: Lægemiddelforskning. p. 16-18

      Research output: Contribution to journal › Journal article › Communication

    38. 2007
    39. Published

      A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

      Vestergaard, Bente, Jensen, M. G., Roessle, M., Kastrup, Jette Sandholm Jensen, van de Weert, Marco, Flink, J. M., Frøkjær, Sven, Gajhede, Michael & Svergun, D. I., 2007, In: PLoS - Biology. 5, 5, p. 1089-1097

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Binding mode of Thioflavin T in insulin amyloid fibrils

      Jensen, M. G., Norrman, M., Flink, J. M., van de Weert, Marco, Bukrinsky, J. T., Schluckebier, G. & Frøkjær, Sven, 2007, In: Journal of Structural Biology. 159, 3, p. 483-497

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Characterisation and physical stability of PEGylated glucagon

      Stigsnæs, P., Frøkjær, Sven, Bjerregaard, S., van de Weert, Marco, Kingshott, P. & Møller, E. H., 2007, In: Internation Journal of Pharmaceutics. 330, 1-2, p. 89-98

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Characterisation of salmon calcitonin in spray-dried powder for inhalation. Effect of chitosan

      Yang, Mingshi, Velaga, S., Yamamoto, H., Takeuchi, H., Kawashima, Y., Hovgaard, L., van de Weert, Marco & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 176-181

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Computational prediction of solubilizers' effect on partitioning

      Høst, J., Christensen, I. T., Jørgensen, Flemming Steen, Frøkjær, Sven & Hovgaard, L., 2007, In: Internation Journal of Pharmaceutics. 329, 1-2, p. 46-52

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Gennembrud i forståelsen af insulinfibrillering

      Jensen, M. G., Vestergaard, Bente, Frøkjær, Sven, Gajhede, Michael, Flink, J. M., van de Weert, Marco, Kastrup, Jette Sandholm Jensen & Svergun, D. I., 2007, In: Lægemiddelforskning. p. 10-11

      Research output: Contribution to journal › Journal article › Communication

    45. Published

      I-125 used for labelling of proteins in an absorption model changes the absorption rate of insulin aspart

      Søhoel, A., Plum, A., Frøkjær, Sven & Thygesen, P., 2007, In: Internation Journal of Pharmaceutics. 330, 1-2, p. 114-120

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test

      Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 160-166

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA)

      Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Journal of Liposome Research. 17, 3-4

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Study on the binding of Thioflavin T to ß-sheet-rich and non-ß-sheet cavities

      Jensen, M. G., Olsen, L., van de Weert, Marco, Flink, J. M., Frøkjær, Sven & Jørgensen, Flemming Steen, 2007, In: Journal of Structural Biology. 158, 3, p. 358-369

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. 2006
    50. Published

      Chemical and thermal stability of insulin: effects of zinc and ligand binding to the insulin zinc-hexamer

      Huus, K., Havelund, S., Olsen, H. B., van de Weert, Marco & Frøkjær, Sven, Nov 2006, In: Pharmaceutical Research. 23, 11, p. 2611-20 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Ligand binding and thermostability of different allosteric states of the insulin zinc-hexamer

      Huus, K., Havelund, S., Olsen, H. B., Sigurskjold, B. W., van de Weert, Marco & Frøkjær, Sven, 28 Mar 2006, In: Biochemistry. 45, 12, p. 4014-4024 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Kinetics of insulin adsorption at the oil-water interface and diffusion properties of adsorbed layers monitored using fluorescence correlation spectroscopy

      Donsmark, J., Jørgensen, Lene, Mollmann, S., Frøkjær, Sven & Rischel, C., 1 Jan 2006, In: Pharmaceutical Research. 23, 1, p. 148-155 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      In vitro evaluation of N-methyl amide tripeptidomimetics as substrates for the human intestinal di-/tri-peptide transporter hPEPT1

      Andersen, R., Nielsen, C. U., Begtrup, M., Jørgensen, Flemming Steen, Larsen, Birger Brodin, Frøkjær, Sven & Steffansen, B., 2006, In: European Journal of Pharmaceutical Sciences. 28, 4, p. 325-35 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Interfacial adsorption of insulin - conformational changes and reversibility of adsorption

      Mollmann, S. H., Jørgensen, Lene, Bukrinsky, J. T., Elofsson, U., Norde, W. & Frøkjær, Sven, 2006, In: European Journal of Pharmaceutical Sciences. 27, 2-3, p. 194-204

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Kinetics of insulin adsorption and gelation at the oil-water interface monitored using fluorescence correlation spectroscopy

      Donsmark, J., Jørgensen, Lene, Mollmann, S. H., Frøkjær, Sven & Rischel, C., 2006, In: Pharmaceutical Research. 23, 1, p. 148-155

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Preparing and evaluating delivery systems for proteins

      Jorgensen, L., Moeller, E. H., van de Weert, Marco, Nielsen, H. M. & Frøkjær, Sven, 2006, In: European Journal of Pharmaceutical Sciences. 29, 3-4, p. 174-82 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    57. 2005
    58. Published

      Factors of importance for a successful delivery system for proteins

      van de Weert, Marco, Jørgensen, Lene, Horn Moeller, E. & Frøkjær, Sven, Nov 2005, In: Expert Opinion on Drug Delivery. 2, 6, p. 1029-37 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    59. Published

      Phase behavior and nanoscale structure of phospholipid membranes incorporated with acylated C14-peptides

      Pedersen, T. B., Kaasgaard, T., Jensen, M., Frøkjær, Sven, Mouritsen, Ole G. & Jørgensen, K., Oct 2005, In: Biophysical Journal. 89, 4, p. 2494-2503 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Thermal dissociation and unfolding of insulin

      Huus, K., Havelund, S., Olsen, H. B., van de Weert, Marco & Frøkjær, Sven, 23 Aug 2005, In: Biochemistry. 44, 33, p. 11171-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Complex coacervation with heparin results in decreased lysozyme stability

      van de Weert, Marco, Bendix Andersen, M. & Frøkjær, Sven, 3 Jan 2005, In: Journal of controlled release : official journal of the Controlled Release Society. 101, 1-3, p. 361-2 2 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    62. Published

      Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media

      Bravo, S. A., Nielsen, C. U., Frøkjær, Sven & Larsen, Birger Brodin, 2005, In: Molecular Pharmaceutics. 2, 2, p. 98-108 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Delivery aspects of small peptides and substrates for peptide transporters

      Steffansen, B., Nielsen, C. U. & Frøkjær, Sven, 2005, In: European Journal of Pharmaceutics and Biopharmaceutics. 60, 4, p. 241-245 4 p.

      Research output: Contribution to journal › Review › Research › peer-review

    64. Published

      Evaluation of statistical design/modeling for prediction of the effect of amino acids on agitation-induced aggregation of human growth hormone and human insulin

      Soenderkaer, S., van de Weert, Marco, Lindgaard Hansen, L., Flink, J. & Frøkjær, Sven, 2005, In: Journal of Drug Delivery Science and Technology. 15, 6, p. 427-434 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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