Lene Jørgensen

Lene Jørgensen

Associate Professor

Member of:


    1. 2021
    2. Published

      Screening of novel excipients for freeze-dried protein formulations

      Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    3. 2020
    4. Published

      Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains

      Mohd Hidzir, N., Anitha, A., Kepa, K., Hill, D. J. T., Jørgensen, Lene & Grondahl, L., 2020, In: Biointerphases. 15, 3, 11 p., 031011.

      Research output: Contribution to journalJournal articlepeer-review

    5. 2019
    6. Published

      Exploring the chemical space for freeze-drying excipients

      Meng-Lund, H., Holm, T. P., Poso, A., Jørgensen, Lene, Rantanen, Jukka & Grohganz, Holger, 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    7. 2018
    8. Published

      Investigation on Secondary Structure Perturbations of Proteins Embedded in Solid Lipid Matrices as a Novel Indicator of their Biological Activity upon In Vitro Release

      Zeeshan, F., Tabbassum, M., Jørgensen, Lene & Medlicott, N. J., 1 Feb 2018, In: AAPS PharmSciTech. 19, 2, p. 769–782

      Research output: Contribution to journalJournal articlepeer-review

    9. Published

      Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy as an Analytical Method to Investigate the Secondary Structure of a Model Protein Embedded in Solid Lipid Matrices

      Zeeshan, F., Tabbassum, M., Jørgensen, Lene & Medlicott, N. J., 2018, In: Applied Spectroscopy. 72, 2, p. 268-279 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    10. Published

      Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

      Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.

      Research output: Contribution to journalJournal articlepeer-review

    11. 2017
    12. Published

      Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

      Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    13. Published

      Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

      Christensen, J. R., Meng-Lund, H., Grohganz, Holger, Poso, A., Laitinen, T., Korhonen, O., Jørgensen, Lene & Pajander, J., 1 May 2017, In: European Journal of Pharmaceutical Sciences. 102, p. 188-195 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    14. Published

      Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity

      Lobbens, E. S. B., Vissing, K. J., Jørgensen, Lene, van de Weert, Marco & Jäger, A. K., 22 Mar 2017, In: Journal of Ethnopharmacology. 200, p. 66-73 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    15. 2016
    16. Published

      Screening of formulation parameters for stabilizing recombinant human serum albumin (rHSA) in liquid formulations

      Baldursdottir, S., Tauhaybeche, M., Pekka Pajander, J., Bukrinski, J. T. & Jørgensen, Lene, Aug 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 1-9 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    17. Published

      Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation

      Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    18. Published

      The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin

      Lobbens, E. S., Foderà, Vito, Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, Lene & van de Weert, Marco, 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.

      Research output: Contribution to journalJournal articlepeer-review

    19. Published

      Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin

      Hedegaard, S. C. F., Cardenas Gomez, M., Barker, R., Jørgensen, Lene & van de Weert, Marco, 2016, In: Langmuir. 32, 28, p. 7241–7249 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    20. 2015
    21. Published

      Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity

      Madsen, C. G., Skov, A., Baldursdottir, S., Rades, Thomas, Jørgensen, Lene & Medlicott, N. J., 7 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 1-7 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    22. Published

      Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces

      Kapp, S. J., Larsson, I., van de Weert, Marco, Cardenas Gomez, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 2, p. 593-601 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    23. Published

      Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

      Kapp, S. J., Larsson, I., van de Weert, Marco, Ćardenas, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 10, p. 3587 1 p.

      Research output: Contribution to journalComment/debate

    24. 2014
    25. Published

      Design and processing of nanogels as delivery systems for peptides and proteins: Therapeutic Delivery

      Arnfast, L., Madsen, C. G., Jørgensen, Lene & Baldursdottir, S., 1 Jun 2014, In: Therapeutic Delivery. 5, 6, p. 691-708 18 p.

      Research output: Contribution to journalJournal articlepeer-review

    26. Published

      Elucidating the mechanisms of protein antigen adsorption to the CAF/NAF liposomal vaccine adjuvant systems: Effect of charge, fluidity and antigen-to-lipid ratio

      Hamborg, M., Rose, F., Jørgensen, Lene, Bjorklund, K., Pedersen, H., Christensen, D. & Foged, Camilla, 25 Apr 2014, In: BBA General Subjects. 1838, 8, p. 2001-2010 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    27. Published

      Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability

      Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, Marco & Jørgensen, Lene, 1 Jan 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    28. Published

      Responsive gelation of hydrophobized linear polymer

      Madsen, C. G., Toeth, J., Jørgensen, Lene, Hietala, S., Baldursdottir, S. G. & Hietala, S., 2014. 4 p.

      Research output: Contribution to conferencePaperResearch

    29. 2013
    30. Published

      The physical stability of the recombinant tuberculosis fusion antigens h1 and h56

      Hamborg, M., Kramer, R., Schanté, C. E., Agger, E. M., Christensen, D., Jørgensen, Lene, Foged, Camilla & Middaugh, C. R., Oct 2013, In: Journal of Pharmaceutical Sciences. 102, 10, p. 3567-78 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    31. Published

      Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs

      Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, Sep 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 1, p. 87-98 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    32. Published

      The challenges in and importance of analysing protein structure and physical stability in complex formulations

      Jørgensen, Lene, Jensen, M. G., Roest, N., Pinholt, C. & van de Weert, Marco, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 347-353 7 p.

      Research output: Contribution to journalReviewpeer-review

    33. Published

      Biologiske lægemidler - fra molekyle til medicin

      Nielsen, Hanne Mørck, Foged, Camilla, Jørgensen, Lene & Frøkjær, Sven, 2013, In: Lægemiddelforskning. p. 12-14

      Research output: Contribution to journalJournal article

    34. Published

      Effect of mixed solvents on polymer conformation –correlation between the Hildebrand/Hansen solubility parameters and the intrinsic viscosity of polymer solutions

      Madsen, C. G., Skov, A., Jørgensen, Lene, Baldursdottir, S. G. & Medlicott, N., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 354-352

      Research output: Contribution to journalConference article

    35. Published

      Influence of acylation on the adsorption of GLP-2 to hydrophobic surfaces

      Pinholt, C., Kapp, S. J., Bukrinsky, J. T., Hostrup, S., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2013, In: International Journal of Pharmaceutics. 440, 1, p. 63-71 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    36. Published

      Protein antigen adsorption to the DDA/TDB liposomal adjuvant: effect on protein structure, stability, and liposome physicochemical characteristics

      Hamborg, M., Jørgensen, Lene, Bojsen, A. R., Christensen, D. & Foged, Camilla, 2013, In: Pharmaceutical Research. 30, 1, p. 140-55 16 p.

      Research output: Contribution to journalJournal articlepeer-review

    37. Published

      Protein nanopharmaceuticals - concepts and safety considerations

      Møller, E. H., Jørgensen, Lene & Medlicott, N. J., 2013, Nanopharmaceutics: the potential application of nanomaterials. Liang, X-J. (ed.). Singapore: World Scientific, p. 49-

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    38. Published

      Towards the understanding of complex fluids in pharmaceutical sciences

      Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.

      Research output: Contribution to journalJournal articlepeer-review

    39. Published

      pH dependent polymer surfactants for hindering BSA adsorption to oil-water interface

      Colak, S., Guzman, P., Medlicott, N., Tehnu, H., Niskanen , J., Alhoranta, A., Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 329-334

      Research output: Contribution to journalConference article

    40. 2012
    41. Published

      Calcipotriol delivery into the skin with PEGylated liposomes

      Knudsen, N. Ø., Rønholt, Stine, Salte, R. D., Jørgensen, Lene, Thormann, T., Basse, L. H., Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 3, p. 532-9 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    42. Published

      Comparison of two methods detecting lysozyme adsorption to oil-water interface in the presence of surfactants

      Baldursdottir, S. G. & Jørgensen, Lene, 2012. 1 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    43. Published

      Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

      Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21

      Research output: Contribution to journalJournal articlepeer-review

    44. Published

      Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration

      Wen, Y., Grøndahl, L., Gallego, M. R., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, 2012, In: Biomacromolecules. 13, p. 905-917

      Research output: Contribution to journalJournal articlepeer-review

    45. Published

      Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor

      Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: International Journal of Pharmaceutics. 428, 1-2, p. 171-177

      Research output: Contribution to journalJournal articlepeer-review

    46. Published

      Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces

      Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2012, In: Langmuir. 28, 3, p. 1804-1815

      Research output: Contribution to journalJournal articlepeer-review

    47. Published

      Formulation technologies to overcome unfavorable properties of peptides and proteins for pulmonary delivery

      Wan, F., Møller, E. H., Yang, Mingshi & Jørgensen, Lene, 2012, In: Drug Discovery Today: Technologies. 9, 2, p. e141-e146

      Research output: Contribution to journalJournal articlepeer-review

    48. Published

      Infrared spectroscopy to characterize protein aggregates

      van de Weert, Marco & Jørgensen, Lene, 2012, Analysis of aggregates and particles in protein pharmaceuticals. Mahler, H-C. & Jiskoot, W. (eds.). Hoboken: Wiley, p. 227-248

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    49. Published

      Interaction of peptidomimetics with bilayer membranes: biophysical characterization and cellular uptake

      Jing, X., Kasimova, M. R., Simonsen, A. H., Jørgensen, Lene, Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2012, In: Langmuir. 28, 11, p. 5167-5175

      Research output: Contribution to journalJournal articlepeer-review

    50. Published

      Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: effects of hydrogen bonding and α-chirality in the β-peptoid residues

      Jing, X., Yang, M., Kasimova, M. R., Malmsten, M., Franzyk, Henrik, Jørgensen, Lene, Foged, Camilla & Nielsen, Hanne Mørck, 2012, In: BBA General Subjects. 1818, 11, p. 2660-2668 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    51. Published

      Protease and amylase stability in the presence of chelators used in laundry detergent applications: correlation between chelator properties and enzyme stability in liquid detergents

      Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, 3, p. 265-276

      Research output: Contribution to journalJournal articlepeer-review

    52. Published

      Rheological Characterization of Lysozyme Adsorption to Oil-Water Interface Using Double Wall Ring Geometry

      Baldursdottir, S. G. & Jørgensen, Lene, 2012.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    53. 2011
    54. Published

      Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation

      Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    55. Published

      Development of biodegradable nanocomposite scaffolds for autologous cell therapy

      Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Everland, H., Møller, E. H. & Nielsen, Hanne Mørck, 1 Jan 2011, In: European Cells and Materials. 21, SUPPL.1, 1 p.

      Research output: Contribution to journalJournal articlepeer-review

    56. Published

      Adsorption of insulin with varying self-association profiles to a solid Teflon surface-Influence on protein structures, fibrillation tendency and thermal stability

      Jørgensen, Lene, Bennedsen, P., Hoffmann, S. V., Pinholt, C., Krogh, R. L., Jensen, M. G., Hostrup, S. & Burkinksky, J. T., 2011, In: European Journal of Pharmaceutical Sciences. 42, 5, p. 509-516

      Research output: Contribution to journalJournal articlepeer-review

    57. Published

      Biodegradable nanocomposite microparticles as drug delivering injectable cell scaffolds

      Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Everland, H., Møller, E. H. & Nielsen, Hanne Mørck, 2011, In: Journal of Controlled Release. 156, 1, p. 11-20

      Research output: Contribution to journalJournal articlepeer-review

    58. Published

      Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

      Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98

      Research output: Contribution to journalJournal articlepeer-review

    59. Published

      Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces

      Pinholt, C., Bukrinsky, J. T., Hostrup, S., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 139-147

      Research output: Contribution to journalJournal articlepeer-review

    60. Published

      Influence of acylation on the adsorption of insulin to hydrophobic surfaces

      Pinholt, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven & Jørgensen, Lene, 2011, In: Pharmaceutical Research. 28, p. 1031-1040

      Research output: Contribution to journalJournal articlepeer-review

    61. Published

      Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation

      Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643

      Research output: Contribution to journalJournal articlepeer-review

    62. Published

      Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity

      Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, p. 478-485

      Research output: Contribution to journalJournal articlepeer-review

    63. Published

      The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations ?

      Pinholt, C., Hartvig, R. A., Medlicott, N. J. & Jørgensen, Lene, 2011, In: Expert Opinion on Drug Delivery. 8, 7, p. 949-964

      Research output: Contribution to journalJournal articlepeer-review

    64. Published

      The influence of size, structure and hydrophilicity of model surfactants on the adsorption of lysozyme to oil-water interface-Interacial shear measurements

      Baldursdóttir, S. G. & Jørgensen, Lene, 2011, In: Colloids and Surfaces B: Biointerfaces. 87, p. 96-102

      Research output: Contribution to journalJournal articlepeer-review

    65. 2010
    66. Published

      A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes

      Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.

      Research output: Contribution to journalJournal article

    67. Published

      Influence of glycosylation on the adsorption of Thermomyces lannuginosus lipase to hydrophobic and hydrophilic surfaces

      Pinholt, C., Fanø, M., Wiberg, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2010, In: European Journal of Pharmaceutical Sciences. 40, 4, p. 273-281

      Research output: Contribution to journalJournal articlepeer-review

    68. Published

      Interfacial complexes between a protein and lipophilic ions at an oil - water interface

      Hartvig, R. A., Méndez, M. A., van de Weert, Marco, Jørgensen, Lene, Østergaard, Jesper, Girault, H. H. & Jensen, H., 2010, In: Analytical Chemistry. 82, 18, p. 7699-7705

      Research output: Contribution to journalJournal articlepeer-review

    69. Published

      Issues in Development of Biodrug Delivery Systems

      Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. Morishita, M. & Park, K. (eds.). 1 ed. Informa Healthcare, p. 13-25

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    70. Published

      Issues in development of biodrug delivery systems

      Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug delivery systems: fundamentals, applications and clinical development. Morishita, M. & Park, K. (eds.). New York: Informa Healthcare, p. 13-25

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    71. Published

      Multivariate analysis of protein physical stability

      Guzman, P., Jørgensen, Lene, Strachan, C., Rades, T. & Medlicott, N., 2010.

      Research output: Contribution to conferenceConference abstract for conferenceResearch

    72. Published

      Penetration of gel and liquid state liposomes into barrier-impaired skin

      Knudsen, N. Ø., Frøkjær, Sven, Hansen, J., Jørgensen, Lene & Foged, Camilla, 2010, In: Journal of Pharmacy and Pharmacology. p. 793

      Research output: Contribution to journalConference articlepeer-review

    73. Published

      Proteiner i lægemidler - de sætter sig alle de forkerte steder

      Baldursdóttir, S. G., Nielsen, S. H., Fullerton, M. & Jørgensen, Lene, 2010, In: Lægemiddelforskning. 2010, p. 43-45

      Research output: Contribution to journalJournal article

    74. Published

       Adsorption of proteins at the oil/water inerface - observation of protein adsorption by interfacial shear stress measurements

      Baldursdóttir, S. G., Fullerton, M. S., Nielsen, S. H. & Jørgensen, Lene, 2010, In: Colloids and Surfaces B: Biointerfaces. 79, p. 41-46

      Research output: Contribution to journalJournal articlepeer-review

    75. 2009
    76. Published

      Challenges in Delivery of Biopharmaceuticals; the Need for Advanced Delivery Systems

      Nielsen, Hanne Mørck & Jørgensen, Lene, 11 Dec 2009, Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines. John Wiley & Sons, Ltd, p. 1-8 8 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    77. Published

      Analysis of protein physical stability in lipid based delivery systems: the challenges of lipid drug delivery systems

      Jørgensen, Lene, Martins, S. & van de Weert, Marco, 2009, In: Journal of Biomedical Nanotechnology. 5, 4, p. 401-408

      Research output: Contribution to journalJournal articlepeer-review

    78. Published

      Biotechnology-based pharmaceuticals

      Jørgensen, Lene, Nielsen, Hanne Mørck & Frøkjær, Sven, 2009, Modern pharmaceutics: applications and advances. Florence, A. T. & Siepmann, J. (eds.). 5 ed. New York: Informa Healthcare, Vol. 2. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    79. Published
    80. Published

      Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis

      Franzen, U., Jørgensen, Lene, Larsen, C. S., Heegaard, N. H. H. & Østergaard, Jesper, 2009, In: Electrophoresis. 30, 15, p. 2711-2719

      Research output: Contribution to journalJournal articlepeer-review

    81. Published

      Infrared spectroscopy of protein pharmaceuticals

      van de Weert, Marco & Jørgensen, Lene, 2009, Advances in Biomedical Spectroscopy: Biological and Biomedical Infrared Spectrocopy. Barth, A. & Haris, P. I. (eds.). Amsterdam: IOS Press, Vol. 2. p. 168-177

      Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

    82. Published

      Lipid based drug delivery systems for proteins: Physical stability of proteins at the oil-water interface

      Jørgensen, Lene, 2009, VDM Verlag Dr. Müller Aktiengesellschaft & C o. KG.

      Research output: Book/ReportBookpeer-review

    83. Published

      Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence  (TIRF)

      Jørgensen, Lene, Krøyer Wood, G., Rosenkrands, I., Petersen, C. & Christensen, D., 2009, In: Journal of Liposome Research. 19, 2, p. 99-104

      Research output: Contribution to journalJournal articlepeer-review

    84. Published

      Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients

      Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230

      Research output: Contribution to journalReview

    85. 2008
    86. Published

      Alternative routes of administration for systemic delivery of protein pharmaceuticals

      Møller, E. H. & Jørgensen, Lene, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 89-94

      Research output: Contribution to journalJournal articlepeer-review

    87. Published

      Drug - liposome distribution phenomena studied by capillary electrophoresis-frontal analysis

      Østergaard, Jesper, Jørgensen, Lene, Thomsen, A. E., Larsen, Susan Weng, Larsen, C. S. & Jensen, H., 2008, In: Electrophoresis. 29, 16, p. 3320 - 3324

      Research output: Contribution to journalJournal articlepeer-review

    88. Published

      Karakterisering af lægemiddelstof-liposom-vekselvirkninger i et kapillar

      Østergaard, Jesper, Franzen, U., Møller, E. H., Jørgensen, Lene, Larsen, C. S. & Jensen, H., 2008, In: Dansk Kemi. 89, 8, p. 27-29

      Research output: Contribution to journalJournal article

    89. Published

      Metode til screening af modificerede proteinlægemidler under opbevaring

      Petersen, C., Jørgensen, Lene, Hostrup, S., Bukrinsky, J. T. & Frøkjær, Sven, 2008, In: Lægemiddelforskning. p. 16-18

      Research output: Contribution to journalJournal article

    90. Published

      Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

      Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

      Research output: Contribution to journalJournal articlepeer-review

    91. 2007
    92. Published

      Liposomer i lægemiddelforskning

      Franzen, U., Jørgensen, Lene, Larsen, C. S., Jensen, H. & Østergaard, Jesper, 2007, In: Lægemiddelforskning. p. 14-15

      Research output: Contribution to journalJournal article

    93. Published

      Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles

      Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17

      Research output: Contribution to journalJournal articlepeer-review

    94. 2006
    95. Published

      Kinetics of insulin adsorption at the oil-water interface and diffusion properties of adsorbed layers monitored using fluorescence correlation spectroscopy

      Donsmark, J., Jørgensen, Lene, Mollmann, S., Frøkjær, Sven & Rischel, C., 1 Jan 2006, In: Pharmaceutical Research. 23, 1, p. 148-155 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    96. Published

      Interfacial adsorption of insulin - conformational changes and reversibility of adsorption

      Mollmann, S. H., Jørgensen, Lene, Bukrinsky, J. T., Elofsson, U., Norde, W. & Frøkjær, Sven, 2006, In: European Journal of Pharmaceutical Sciences. 27, 2-3, p. 194-204

      Research output: Contribution to journalJournal articlepeer-review

    97. Published

      Kinetics of insulin adsorption and gelation at the oil-water interface monitored using fluorescence correlation spectroscopy

      Donsmark, J., Jørgensen, Lene, Mollmann, S. H., Frøkjær, Sven & Rischel, C., 2006, In: Pharmaceutical Research. 23, 1, p. 148-155

      Research output: Contribution to journalJournal articlepeer-review

    98. 2005
    99. Published

      Factors of importance for a successful delivery system for proteins

      van de Weert, Marco, Jørgensen, Lene, Horn Moeller, E. & Frøkjær, Sven, Nov 2005, In: Expert Opinion on Drug Delivery. 2, 6, p. 1029-37 9 p.

      Research output: Contribution to journalReviewpeer-review

    100. 2004
    101. Published

      Probing structural changes of proteins incorporated into water-in-oil emulsions

      Jørgensen, Lene, van de Weert, Marco, Vermehren, C., Bjerregaard, S. & Frøkjær, Sven, Jul 2004, In: Journal of Pharmaceutical Sciences. 93, 7, p. 1847-59 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    102. Published

      In vitro release of insulin aspart incorporated into water-in-oil emulsions

      Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Drug Delivery Science and Technology. 14, 6, p. 455-459

      Research output: Contribution to journalJournal articlepeer-review

    103. Published

      Micropipette manipulation a technique to evaluate the stability of water-in-oil emulsions containing proteins

      Jørgensen, Lene, Kim, D. H., Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Pharmaceutical Sciences. 93, 12, p. 2994-3003

      Research output: Contribution to journalJournal articlepeer-review

    104. 2003
    105. Published

      Secondary structure alteration in insulin and growth hormone water-in-oil emulsions

      Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2003, In: Internation Journal of Pharmaceutics. 254, 1, p. 7-10

      Research output: Contribution to journalJournal articlepeer-review

    ID: 1299770