Lene Jørgensen

Lene Jørgensen

Associate Professor

Member of:


    1. 2021
    2. Published

      Screening of novel excipients for freeze-dried protein formulations

      Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    3. 2020
    4. Published

      Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains

      Mohd Hidzir, N., Anitha, A., Kepa, K., Hill, D. J. T., Jørgensen, Lene & Grondahl, L., 2020, In: Biointerphases. 15, 3, 11 p., 031011.

      Research output: Contribution to journalJournal articlepeer-review

    5. 2019
    6. Published

      Exploring the chemical space for freeze-drying excipients

      Meng-Lund, H., Holm, T. P., Poso, A., Jørgensen, Lene, Rantanen, Jukka & Grohganz, Holger, 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    7. 2018
    8. Published

      Investigation on Secondary Structure Perturbations of Proteins Embedded in Solid Lipid Matrices as a Novel Indicator of their Biological Activity upon In Vitro Release

      Zeeshan, F., Tabbassum, M., Jørgensen, Lene & Medlicott, N. J., 1 Feb 2018, In: AAPS PharmSciTech. 19, 2, p. 769–782

      Research output: Contribution to journalJournal articlepeer-review

    9. Published

      Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy as an Analytical Method to Investigate the Secondary Structure of a Model Protein Embedded in Solid Lipid Matrices

      Zeeshan, F., Tabbassum, M., Jørgensen, Lene & Medlicott, N. J., 2018, In: Applied Spectroscopy. 72, 2, p. 268-279 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    10. Published

      Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

      Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.

      Research output: Contribution to journalJournal articlepeer-review

    11. 2017
    12. Published

      Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

      Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    13. Published

      Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

      Christensen, J. R., Meng-Lund, H., Grohganz, Holger, Poso, A., Laitinen, T., Korhonen, O., Jørgensen, Lene & Pajander, J., 1 May 2017, In: European Journal of Pharmaceutical Sciences. 102, p. 188-195 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    14. Published

      Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity

      Lobbens, E. S. B., Vissing, K. J., Jørgensen, Lene, van de Weert, Marco & Jäger, A. K., 22 Mar 2017, In: Journal of Ethnopharmacology. 200, p. 66-73 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    15. 2016
    16. Published

      Screening of formulation parameters for stabilizing recombinant human serum albumin (rHSA) in liquid formulations

      Baldursdottir, S., Tauhaybeche, M., Pekka Pajander, J., Bukrinski, J. T. & Jørgensen, Lene, Aug 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 1-9 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    17. Published

      Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation

      Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    18. Published

      The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin

      Lobbens, E. S., Foderà, Vito, Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, Lene & van de Weert, Marco, 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.

      Research output: Contribution to journalJournal articlepeer-review

    19. Published

      Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin

      Hedegaard, S. C. F., Cardenas Gomez, M., Barker, R., Jørgensen, Lene & van de Weert, Marco, 2016, In: Langmuir. 32, 28, p. 7241–7249 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    20. 2015
    21. Published

      Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity

      Madsen, C. G., Skov, A., Baldursdottir, S., Rades, Thomas, Jørgensen, Lene & Medlicott, N. J., 7 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 1-7 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    22. Published

      Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces

      Kapp, S. J., Larsson, I., van de Weert, Marco, Cardenas Gomez, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 2, p. 593-601 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    23. Published

      Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

      Kapp, S. J., Larsson, I., van de Weert, Marco, Ćardenas, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 10, p. 3587 1 p.

      Research output: Contribution to journalComment/debate

    24. 2014
    25. Published

      Design and processing of nanogels as delivery systems for peptides and proteins: Therapeutic Delivery

      Arnfast, L., Madsen, C. G., Jørgensen, Lene & Baldursdottir, S., 1 Jun 2014, In: Therapeutic Delivery. 5, 6, p. 691-708 18 p.

      Research output: Contribution to journalJournal articlepeer-review

    26. Published

      Elucidating the mechanisms of protein antigen adsorption to the CAF/NAF liposomal vaccine adjuvant systems: Effect of charge, fluidity and antigen-to-lipid ratio

      Hamborg, M., Rose, F., Jørgensen, Lene, Bjorklund, K., Pedersen, H., Christensen, D. & Foged, Camilla, 25 Apr 2014, In: BBA General Subjects. 1838, 8, p. 2001-2010 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    27. Published

      Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability

      Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, Marco & Jørgensen, Lene, 1 Jan 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    28. Published

      Responsive gelation of hydrophobized linear polymer

      Madsen, C. G., Toeth, J., Jørgensen, Lene, Hietala, S., Baldursdottir, S. G. & Hietala, S., 2014. 4 p.

      Research output: Contribution to conferencePaperResearch

    29. 2013
    30. Published

      The physical stability of the recombinant tuberculosis fusion antigens h1 and h56

      Hamborg, M., Kramer, R., Schanté, C. E., Agger, E. M., Christensen, D., Jørgensen, Lene, Foged, Camilla & Middaugh, C. R., Oct 2013, In: Journal of Pharmaceutical Sciences. 102, 10, p. 3567-78 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    31. Published

      Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs

      Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, Sep 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 1, p. 87-98 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    32. Published

      The challenges in and importance of analysing protein structure and physical stability in complex formulations

      Jørgensen, Lene, Jensen, M. G., Roest, N., Pinholt, C. & van de Weert, Marco, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 347-353 7 p.

      Research output: Contribution to journalReviewpeer-review

    33. Published

      Biologiske lægemidler - fra molekyle til medicin

      Nielsen, Hanne Mørck, Foged, Camilla, Jørgensen, Lene & Frøkjær, Sven, 2013, In: Lægemiddelforskning. p. 12-14

      Research output: Contribution to journalJournal article

    34. Published

      Effect of mixed solvents on polymer conformation –correlation between the Hildebrand/Hansen solubility parameters and the intrinsic viscosity of polymer solutions

      Madsen, C. G., Skov, A., Jørgensen, Lene, Baldursdottir, S. G. & Medlicott, N., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 354-352

      Research output: Contribution to journalConference article

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    ID: 1299770