Kasper Dyrberg Rand

Kasper Dyrberg Rand

Professor


  1. 2024
  2. Published

    Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

    Grauslund, L. R., Ständer, S., Veggi, D., Andreano, E., Rand, Kasper Dyrberg & Norais, N., 2024, In: Molecular & cellular proteomics : MCP. 23, 3, 100734.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Conformationally Restricted Glycopeptide Backbone Inhibits Gas-Phase H/D Scrambling between Glycan and Peptide Moieties

    Code, C., Qiu, D., Solov'yov, I. A., Lee, J., Shin, H., Roland, C., Sagui, C., Houde, D., Rand, Kasper Dyrberg & Jørgensen, T. J. D., 2023, In: Journal of the American Chemical Society. 145, 44, p. 23925-23938

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS

    Lambert, Thomas Ole Tandrup, Gramlich, M., Stutzke, L., Smith, L., Deng, D., Kaiser, P. D., Rothbauer, U., Benesch, J. L. P., Wagner, C., Koenig, M., Pompach, P., Novak, P., Zeck, A. & Rand, Kasper Dyrberg, 2023, In: Journal of the American Society for Mass Spectrometry. 34, 11, p. 2556–2566

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction

    Sheff, J., Kelly, J., Foss, M., Brunette, E., Kemmerich, K., van Faassen, H., Raphael, S., Hussack, G., Comamala, G., Rand, Kasper Dyrberg & Stanimirovic, D. B., 2023, In: Journal of Biochemistry. 173, 2, p. 95-105

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2022
  8. Published

    PNGase H+ variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N‐glycans and HDX‐MS analysis of glycoproteins.

    Guo, R., Zhang, T., Lambert, Thomas Ole Tandrup, Wang, T., Voglmeir, J., Rand, Kasper Dyrberg & Liu, L., 2022, In: Rapid Communications in Mass Spectrometry. 36, 21, 9 p., e9376.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Probing the impact of temperature and substrates on the conformational dynamics of the Neurotransmitter:Sodium symporter LeuT

    Calugareanu, D., Möller, I. R., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2022, In: Journal of Molecular Biology. 434, 2, 15 p., 167356.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The dopamine transporter antiports potassium to increase the uptake of dopamine

    Schmidt, S. G., Malle, M. G., Nielsen, A. K., Bohr, S. S., Pugh, Ciara Frances, Nielsen, Jeppe Cederholm, Poulsen, I. H., Rand, Kasper Dyrberg, Hatzakis, Nikos & Loland, Claus Juul, 2022, In: Nature Communications. 13, 1, 12 p., 2446.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2021
  12. Published

    Conformational dynamics of free and membrane-bound human Hsp70 in model cytosolic and endo-lysosomal environments

    Calvaresi, V., Truelsen, L. T., Larsen, S. B., Petersen, N. H. T., Kirkegaard, T. & Rand, Kasper Dyrberg, 2021, In: Communications Biology . 4, 1369.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Epitope Mapping of Polyclonal Antibodies by Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS)

    Ständer, S., Grauslund, L. R., Scarselli, M., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 34, p. 11669–11678

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies

    Grauslund, L. R., Calvaresi, V., Pansegrau, W., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Journal of the American Society for Mass Spectrometry. 32, 7, p. 1575–1582

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Hydrogen-Deuterium Exchange Mass Spectrometry with Integrated Size-Exclusion Chromatography for Analysis of Complex Protein Samples

    Calvaresi, V., Redsted, A., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 33, p. 11406–11414

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Hydrogen/Deuterium Exchange Mass Spectrometry with Integrated Electrochemical Reduction and Microchip-Enabled Deglycosylation for Epitope Mapping of Heavily Glycosylated and Disulfide-Bonded Proteins

    Comamala, G., Krogh, C. C., Nielsen, V. S., Kutter, Jörg P., Voglmeir, J. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 49, p. 16330–16340

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry

    Merkle, P. S., Trabjerg, Esben, Hongjian, S., Ferber, M., Cuendet, M. A., Jorgensen, T. J. D., Luescher, I., Irving, M., Zoete, V., Michielin, O. & Rand, Kasper Dyrberg, 2021, In: Biochemistry. 60, 11, p. 859-872

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Revealing the dynamic allosteric changes required for formation of the cysteine synthase complex by hydrogen-deuterium exchange mass spectrometry

    Rosa, B., Dickinson, E. R., Marchetti, M., Campanini, B., Pioselli, B., Bettati, S. & Rand, Kasper Dyrberg, 2021, In: Molecular and Cellular Proteomics. 20, 12 p., 100098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2020
  20. Published

    Hydrogen/deuterium exchange mass spectrometry with improved electrochemical reduction enables comprehensive epitope mapping of a therapeutic antibody to the cysteine-knot containing vascular endothelial growth factor

    Comamala, G., Wagner, C., de la Torre, P. S., Jakobsen, R. U., Hilger, M., Brouwer, H. & Rand, Kasper Dyrberg, 8 Jun 2020, In: Analytica Chimica Acta. 1115, p. 41-51 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    An intact C-terminal end of albumin is required for its long half-life in humans

    Nilsen, J., Trabjerg, Esben, Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., 20 Apr 2020, In: Communications Biology. 3, 1, 11 p., 181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines

    Castelli, R., Scalvini, L., Vacondio, F., Lodola, A., Anselmi, M., Vezzosi, S., Carmi, C., Bassi, M., Ferlenghi, F., Rivara, S., Möller, I. R., Rand, K. D., Daglian, J., Wei, D., Dotsey, E. Y., Ahmed, F., Jung, K-M., Stella, N., Singh, S., Mor, M. & 1 others, Piomelli, D., 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1261-1280

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis

    Wu, S., Nguyen, T. T. T. N., Moroz, O. V., Turkenburg, J. P., Nielsen, J. E., Wilson, K. S., Rand, Kasper Dyrberg & Teilum, Kaare, 2020, In: PeerJ. 8, 17 p., e9408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Deglycosylation by the Acidic Glycosidase PNGase H+ Enables Analysis of N-Linked Glycoproteins by Hydrogen/Deuterium Exchange Mass Spectrometry

    Comamala, G., Madsen, J. B., Voglmeir, J., Du, Y., Jensen, P. F., Østerlund, E. C., Trelle, M. B. & Rand, Kasper Dyrberg, 2020, In: Journal of the American Society for Mass Spectrometry. 31, 11, p. 2305-2312

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Discovery of Highly Active Recombinant PNGase H+ Variants Through the Rational Exploration of Unstudied Acidobacterial Genomes

    Guo, R., Comamala, G., Yang, H., Gramlich, M., Du, Y., Wang, T., Zeck, A., Rand, Kasper Dyrberg, Liu, L. & Voglmeir, J., 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 7 p., 741.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid

    Fogh, J. R., Jacobsen, A., Nguyen, T. T. T. N., Rand, Kasper Dyrberg & Olsen, L. R., 2020, In: Analytical and Bioanalytical Chemistry. 412, p. 1653-1661

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Molecular Basis of the Mechanisms Controlling MASTL

    Hermida, D., Mortuza, G. B., Pedersen, Anna-Kathrine, Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS

    Möller, I. R., Merkle, P. S., Calugareanu, D., Comamala, G., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2020, In: Journal of Proteomics. 225, 103845.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Thiol-ene microfluidic chip for fast on-chip sample clean-up, separation and ESI mass spectrometry of peptides and proteins

    Svejdal, R. R., Sticker, Drago, Sønderby, C., Kutter, Jörg P. & Rand, Kasper Dyrberg, 2020, In: Analytica Chimica Acta. 1140, p. 168-177 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2019
  31. Published

    An intact C-terminal end of albumin is required for long serum half-life

    Nilsen, J., Trabjerg, E., Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., Dec 2019, p. 19. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

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ID: 34783804