Bjarne Styrishave

Bjarne Styrishave

Associate Professor

Member of:


    1. 2024
    2. Published

      Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration

      Westgate, C. S. J., Kamp-Jensen, C., Israelsen, I. M. E., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C. A., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rigmor Højland & Eftekhari, S., 2024, In: British Journal of Pharmacology. 181, 1, p. 70-86

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Ancient forest plants possess cytotoxic properties causing liver cancer HepG2 cell apoptosis

      Yue, X., Ling Ma, N., Zhong, J., Yang, H., Chen, H., Yang, Y., Lam, S. S., Yan, L., Styrishave, Bjarne, Ciesielski, T. M., Peng, W. X. & Sonne, C., 2024, In: Environmental Research. 241, 9 p., 117474.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension

      Wardman, Jonathan Henry, Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Jensen, Mette Nyholm, Wilhjelm, J. E., Styrishave, Bjarne, Hamann, Steffen, Heegaard, Steffen, Sinclair, A. J. & MacAulay, Nanna, 2024, In: Fluids and Barriers of the CNS. 21, 1, 20 p., 10.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      The intrafollicular concentrations of biologically active cortisol in women rise abruptly shortly before ovulation and follicular rupture

      Johannsen, Malene Louise, Poulsen, L. C., Mamsen, L. S., Grøndahl, M. L., Englund, A. L. M., Lauritsen, N. L., Carstensen, E. C., Styrishave, Bjarne & tcg964, tcg964, 2024, In: Human Reproduction. 39, 3, p. 578-585

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. 2023
    7. Published

      A New Ellagic Acid Rhamnoside from Synadenium glaucescens and Its Cytotoxicity Evaluation

      Rwegoshora, F., Mabiki, F., Machumi, F., Chacha, M., Styrishave, Bjarne & Cornett, Claus, 2023, In: Chemistry of Natural Compounds. 59, 4, p. 670-674

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Cycle-dependent sex differences in expression of membrane proteins involved in cerebrospinal fluid secretion at rat choroid plexus

      Israelsen, I. M. E., Kamp-Jensen, C., Westgate, C. S. J., Styrishave, Bjarne, Jensen, Rigmor Højland & Eftekhari, S., 2023, In: BMC Neuroscience. 24, 1, 11 p., 60.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Effects of empagliflozin on erythropoiesis in heart failure: data from the Empire HF trial

      Fuchs Andersen, C., Omar, M., Glenthøj, Andreas Birkedal, Fassi, Daniel El , Møller, H. J., Kurtzhals, Jørgen, Styrishave, Bjarne, Kistorp, Caroline Michaela Nervil, Tuxen, C., Poulsen, M. K., Faber, Jens, Køber, Lars Valeur, Gustafsson, Finn, Møller, J. E., Schou, Morten & Jensen, J., 2023, In: European Journal of Heart Failure. 25, 2, p. 226-234

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      High-throughput screening of ancient forest plant extracts shows cytotoxicity towards triple-negative breast cancer

      Li, Y., Ling Ma, N., Chen, H., Zhong, J., Zhang, D., Peng, W., Shiung Lam, S., Yang, Y., Yue, X., Yan, L., Wang, T., Styrishave, Bjarne, Maciej Ciesielski, T. & Sonne, C., 2023, In: Environment International. 181, 10 p., 108279.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

      Wardman, Jonathan Henry, Jensen, Mette Nyholm, Andreassen, Søren Norge, Styrishave, Bjarne, Wilhjelm, J. E., Sinclair, A. J. & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 44.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Optimization of HPLC–MS/MS method for determination of antimalarial adulterants in herbal products

      Mwankuna, C. J., Kiros, F., Mariki, E. E., Mabiki, F. P., Malebo, H. M., Mdegela, R. H. & Styrishave, Bjarne, 2023, In: Analytical Sciences. 39, p. 407-416

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Testosterone and persistent organic pollutants in East Greenland male polar bears (Ursus maritimus)

      Ciesielski, T. M., Sonne, C., Smette, E. I., Villanger, G. D., Styrishave, Bjarne, Letcher, R. J., Hitchcock, D. J., Dietz, R. & Jenssen, B. M., 2023, In: Heliyon. 9, 3, 10 p., e13263.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Thin Layer Chromatographic Method for Detection of Conventional Drug Adulterants in Herbal Products

      Mwankuna, C. J., Mariki, E. E., Mabiki, F. P., Malebo, H. M., Styrishave, Bjarne & Mdegela, R. H., 2023, In: Separations. 10, 1, 10 p., 23.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Towards a microfluidic H295R steroidogenesis assay—biocompatibility study and steroid detection on a thiol-ene-based chip

      Despicht, C., Munkboel, C. H., Chou, H. N., Ertl, P., Rothbauer, M., Kutter, Jörg P., Styrishave, Bjarne & Kretschmann, A., 2023, In: Analytical and Bioanalytical Chemistry. 415, p. 5421–5436

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. 2022
    17. Published

      A HPLC-MS/MS method for screening of selected antibiotic adulterants in herbal drugs

      Mwankuna, C. J., Uwamaliya, G. A., Mariki, E. E., Mabiki, F., Malebo, H. M., Mdegela, R. & Styrishave, Bjarne, 2022, In: Analytical Methods. 14, 10, p. 1060-1068

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Anti-Newcastle Disease Virus activity of 3β and 3α Friedelanol Triterpenoids from the leaves of Synadenium glaucescens Pax

      Credo, D., Mabiki, F. P., Machumi, F., Chacha, M., Cornett, Claus & Styrishave, Bjarne, 2022, In: Tropical Biomedicine. 39, 2, p. 257-264 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Cortisol in Manure from Cattle Enclosed with Nofence Virtual Fencing

      Sonne, C., Alstrup, A. K. O., Pertoldi, C., Frikke, J., Linder, A. C. & Styrishave, Bjarne, 2022, In: Animals. 12, 21, 11 p., 3017.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Follicular fluid steroid hormones and in vitro embryo development in Duroc and Landrace pigs

      Jochems, R., Gaustad, A. H., Styrishave, Bjarne, Zak, L. J., Oskam, I. C., Grindflek, E., Myromslien, F. D., Kommisrud, E. & Krogenæs, A. K., 2022, In: Theriogenology. 190, p. 15-21

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Isolation and toxicity evaluation of feruloyl ester and other triterpenoids from Synadenium glaucescens Pax

      Rwegoshora, F., Mabiki, F., Machumi, F., Chacha, M., Styrishave, Bjarne & Cornett, Claus, 2022, In: The Journal of Phytopharmacology. 11, 5, p. 347-352

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      LC-MS/MS Method for Determination of Non-opioid Analgesics Adulterants in Herbal Medicines

      Mpanyakavili, A. L., Mwankuna, C. J., Mabiki, F. P. & Styrishave, Bjarne, 2022, In: Chemistry Africa. 5, p. 2149–2162

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Reservoir of Antibiotic Residues and Resistant Coagulase Negative Staphylococci in a Healthy Population in the Greater Accra Region, Ghana

      Bekoe, S. O., Hane-Weijman, S., Trads, S. L., Orman, E., Opintan, J., Hansen, M., Frimodt-Møller, N. & Styrishave, Bjarne, 2022, In: Antibiotics. 11, 1, 12 p., 119.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

      Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      The Acute and Chronic Effects of Acetazolamide and Topiramate on Intracranial Pressure and CSF Secretion

      Westgate, C., Kamp-Jensen, C., Israelsen, I., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rasmus Herlo Beenfeldt & Eftekhari, S., 2022, In: Journal of Headache and Pain. 23, Suppl. 1, 1 p., P218.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    26. 2021
    27. Published

      Acetaminophen metabolism revisited using non-targeted analyses: Implications for human biomonitoring

      David, A., Chaker, J., Leger, T., Al-Salhi, R., Dalgaard, M. D., Styrishave, Bjarne, Bury, D., Koch, H. M., Jegou, B. & Kristensen, D. M., 2021, In: Environment International. 149, 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Baseline Hepcidin Does Not Predict the Response to Iron Therapy in Pregnant Women with Iron Deficiency

      Hansen, R., Kurtzhals, Jørgen, Styrishave, Bjarne & Bischof, Charlotte Holm, 2021, In: Blood. 138, Suppl 1, 3076.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    29. Published

      Is the unique benzodiazepine structure interacting with CYP enzymes to affect steroid synthesis in vitro?

      Johannsen, Malene Louise, Munkboel, C. H., Jørgensen, Flemming Steen & Styrishave, Bjarne, 2021, In: Journal of Steroid Biochemistry and Molecular Biology. 205, 10 p., 105765.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Oral anti-diabetic drugs as endocrine disruptors in vitro - No evidence for additive effects in binary mixtures

      Munkboel, C. H., Hansen, H. S., Jessen, J. B., Johannsen, Malene Louise & Styrishave, Bjarne, 2021, In: Toxicology in Vitro. 70, 12 p., 105007.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. 2020
    32. Published

      Antibiotic Uptake by Plant Model

      Azanu, D., Jorgensen, S. E., Darko, G., Styrishave, Bjarne & Abaidoo, R. C., 2020, In: Environmental Modeling & Assessment. 25, 4, p. 545-553 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Detection and quantification of antibiotic residues in urine samples of healthy individuals from rural and urban communities in Ghana using a validated SPE-LC-MS/MS method

      Bekoe, S. O., Orman, E., Asare-Nkansah, S., Sorensen, A. M. L., Bjorklund, E., Adosraku, R. K., Hansen, M. & Styrishave, Bjarne, 2020, In: SN Applied Sciences. 2, 11, 11 p., 1903.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Exposure of consumers to substandard antibiotics from selected authorised and unauthorised medicine sales outlets in Ghana

      Bekoe, S. O., Ahiabu, M. A., Orman, E., Tersbøl, Britt Pinkowski, Adosraku, R. K., Hansen, M., Frimodt-Møller, N. & Styrishave, Bjarne, 2020, In: Tropical Medicine and International Health. 25, 8, p. 962-975 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Measuring and validating concentrations of steroid hormones in the skin of bottlenose dolphins (Tursiops truncatus)

      Bechshoft, T., Wright, A. J., Styrishave, Bjarne & Houser, D., 2020, In: Conservation Physiology. 8, 1, 13 p., 032.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Microcystins and Microcystis aeruginosa PCC7806 extracts modulate steroidogenesis differentially in the human H295R adrenal model

      Mallia, V., Verhaegen, S., Styrishave, Bjarne, Eriksen, G. S., Johannsen, Malene Louise, Ropstad, E. & Uhlig, S., 2020, In: PLoS ONE. 15, 12, 18 p., 0244000.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Sled Dogs as Sentinel Species for Monitoring Arctic Ecosystem Health

      Sonne, C., Letcher, R. J., Jenssen, B. M., Desforges, J., Eulaers, I., Andersen-Ranberg, E., Gustavson, K., Bossi, R., Styrishave, Bjarne, Sinding, Mikkel Holger Strander & Dietz, R., 2020, Pets as Sentinels, Forecasters and Promoters of Human Health. Pastorinho, M. R. & Sousa, A. C. A. (eds.). Springer, p. 21-45 25 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    38. 2019
    39. Published

      Current state of knowledge on biological effects from contaminants on arctic wildlife and fish

      Dietz, R., Letcher, R. J., Desforges, J-P., Eulaers, I., Sonne, C., Wilson, S., Andersen-Ranberg, E., Basu, N., Barst, B. D., Bustnes, J. O., Bytingsvik, J., Ciesielski, T. M., Drevnick, P. E., Gabrielsen, G., Haarr, A., Hylland, K., Jenssen, B. M., Levin, M., McKinney, M. A., Norregaard, R. D. & 50 others, Pedersen, K. E., Provencher, J., Styrishave, Bjarne, Tartu, S., Aars, J., Ackerman, J. T., Rosing-Asvid, A., Barrett, R., Bignert, A., Borns, E. W., Branigan, M., Braune, B., Bryan, C. E., Dam, M., Eagles-Smith, C. A., Evans, M., Evans, T. J., Fisk, A. T., Gamberg, M., Gustavson, K., Hartman, C. A., Helander, B., Herzog, M. P., Hoekstra, P. F., Houde, M., Hoydal, K., Jackson, A. K., Kucklick, J., Lie, E., Loseto, L., Mallory, M. L., Miljeteig, C., Mosbech, A., Muir, D. C. G., Nielsen, S. T., Peacock, E., Pedro, S., Peterson, S. H., Polder, A., Riget, F. F., Roach, P., Saunes, H., Sinding, M. S., Skaare, J. U., Sondergaard, J., Stenson, G., Stern, G., Treu, G., Schuur, S. S. & Vikingsson, G., 15 Dec 2019, In: Science of the Total Environment. 696, 40 p., 133792.

      Research output: Contribution to journalReviewResearchpeer-review

    40. Published

      State of knowledge on current exposure, fate and potential health effects of contaminants in polar bears from the circumpolar Arctic

      Routti, H., Atwood, T. C., Bechshoft, T., Boltunov, A., Ciesielski, T. M., Desforges, J., Dietz, R., Gabrielsen, G., Jenssen, B. M., Letcher, R. J., McKinney, M. A., Morris, A. D., Riget, F. F., Sonne, C., Styrishave, Bjarne & Tartu, S., 10 May 2019, In: Science of the Total Environment. 664, p. 1063-1083

      Research output: Contribution to journalReviewResearchpeer-review

    41. Published

      The classic azole antifungal drugs are highly potent endocrine disruptors in vitro inhibiting steroidogenic CYP enzymes at concentrations lower than therapeutic Cmax

      Munkboel, C. H., Rasmussen, T. B., Elgaard, C., Olesen, M. L. K., Kretschmann, A. C. & Styrishave, Bjarne, 2019, In: Toxicology. 425, 152247.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. 2018
    43. Published

      Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools

      Castberg, F. C., Sarbah, E. W., Koram, K. A., Opoku, N., Ofori, M. F., Styrishave, Bjarne, Hviid, Lars & Kurtzhals, Jørgen, 11 Dec 2018, In: Malaria Journal. 17, 1, 464.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Occurrence, removal and risk assessment of steroid hormones in two wastewater stabilization pond systems in Morogoro, Tanzania

      Damkjaer, K., Weisser, J. J., Msigala, S. C., Mdegela, R. & Styrishave, Bjarne, Dec 2018, In: Chemosphere. 212, p. 1142-1154

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro

      Munkboel, C. H., Christensen, L. R., Islin, J., Bonomo, S., Olsen, L., Jørgensen, Flemming Steen & Styrishave, Bjarne, Oct 2018, In: Biology of Reproduction. 99, 4, p. 888-897

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Sertraline Suppresses Testis and Adrenal Steroid Production and Steroidogenic Gene Expression While Increasing LH in Plasma of Male Rats Resulting in Compensatory Hypogonadism

      Munkboel, C. H., Larsen, L. W., Weisser, J. J., Kristensen, D. M. & Styrishave, Bjarne, Jun 2018, In: Toxicological Sciences. 163, 2, p. 609-619

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Occurrence and risk assessment of antibiotics in water and lettuce in Ghana

      Azanu, D., Styrishave, Bjarne, Darko, G., Weisser, J. J. & Abaidoo, R. C., 1 May 2018, In: Science of the Total Environment. 622-23, p. 293-305

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Atorvastatin decreases steroid production in H295R cells and in major endocrine tissues of male rats

      Munkboel, C. H., Baake, M. L. K. & Styrishave, Bjarne, May 2018, In: Archives of Toxicology. 92, 5, p. 1703-1715

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Effects of antihistamines on the H295R steroidogenesis - Autocrine up-regulation following 3 beta-HSD inhibition

      Munkboel, C. H., Hasselstrom, S. B., Kristensen, D. M. & Styrishave, Bjarne, Apr 2018, In: Toxicology in Vitro. 48, p. 302-309

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Assessment of the analgesic dipyrone as a possible (anti) androgenic endocrine disruptor

      Passoni, M. T., Kristensen, M. N., Morais, R. N., Woitkowiak, C., Boareto, A. C., da Silva Amaral, B. A., Grechi, N., Dalsenter, P. R., Munkboel, C. H., Styrishave, Bjarne, Kristensen, D. M., Gomes, C., van Ravenzwaay, B. & Martino-Andrade, A. J., 15 Mar 2018, In: Toxicology Letters. 285, p. 139-147

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Steroidogenic disruptive effects of the serotonin-noradrenaline reuptake inhibitors duloxetine, venlafaxine and tramadol in the H295R cell assay and in a recombinant CYP17 assay

      Islin, J., Munkboel, C. H. & Styrishave, Bjarne, Mar 2018, In: Toxicology in Vitro. 47, p. 63-71

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

      Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, Abigail, Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, Bjarne, Antignac, J., Le Bizec, B., Platel, C., Hay-Schmidt, Anders, Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, Karsten, Brunak, Søren, Kjær, Michael, Juul, Anders & Jégou, B., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. e715-e724 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. 2017
    54. Published

      A veterinary perspective on One Health in the Arctic

      Sonne, C., Letcher, R. J., Jenssen, B. M., Desforges, J. P., Eulaers, I., Andersen-Ranberg, E., Gustavson, K., Styrishave, Bjarne & Dietz, R., Dec 2017, In: Acta Veterinaria Scandinavica. 59, 11 p., 84.

      Research output: Contribution to journalReviewResearchpeer-review

    55. Published

      Relationships between POPs, biometrics and circulating steroids in male polar bears (Ursus maritimus) from Svalbard

      Ciesielski, T. M., Hansen, I. T., Bytingsvik, J., Hansen, M., Lie, E., Aars, J., Jenssen, B. M. & Styrishave, Bjarne, Nov 2017, In: Environmental Pollution. 230, p. 598-608 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Steroid hormones and persistent organic pollutants in plasma from North-eastern Atlantic pilot whales

      Hoydal, K. S., Styrishave, Bjarne, Ciesielski, T. M., Letcher, R. J., Dam, M. & Jenssen, B. M., Nov 2017, In: Environmental Research. 159, p. 613-621 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      The six most widely used selective serotonin reuptake inhibitors decrease androgens and increase estrogens in the H295R cell line

      Hansen, C. H., Larsen, L. W., Sørensen, A. M., Halling-Sørensen, B. & Styrishave, Bjarne, Jun 2017, In: Toxicology in Vitro. 41, p. 1-11 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors

      Larsen, M., Hansen, C. H., Rasmussen, T. B., Styrishave, Bjarne, Olsen, L. & Jørgensen, Flemming Steen, 28 Feb 2017, In: Chemical Communications. 53, 3118, 4 p., 3118.

      Research output: Contribution to journalJournal articleResearchpeer-review

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