Birger Brodin Larsen

Birger Brodin Larsen

Professor


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  1. Published

    Characterization of in vitro blood-brain barrier models

    Helms, H. C. C., Eriksson, A. H., Nielsen, C. U., Waagepetersen, Helle S., Walls, Anne Byriel & Larsen, Birger Brodin, 9 Aug 2009. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  2. Published

    Excitatory amino acid transporter-1 (EAAT1) is the main transporter responsible for abluminal uptake of L-glutamate in bovine brain endothelial cells

    Helms, H. C. C., Groth, S., Mikél, M., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 27 May 2013.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  3. Published

    A Tight Blood-Brain Barrier Model Displays Brain-to-Blood Efflux of Substrates for the ABC-Transporters, P-gp, BCRP and MRP-1

    Helms, H. C. C., Hersom, M. N. S., Kuhlmann, L. B., Badolo, L., Nielsen, C. U. & Larsen, Birger Brodin, 11 Sep 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  4. Published

    Glutamate efflux from brain to blood - Studies in an in vitro blood-brain barrier model

    Helms, H. C. C., Madelung, R., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2012.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  5. Published

    Efflux transporter expression in a tight in vitro model of the blood brain barrier

    Helms, H. C. C., Hersom, M. N. S., Kuhlmann, L. B., Badolo, L., Nielsen, C. U. & Larsen, Birger Brodin, 10 Dec 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  6. Published

    In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

    Helms, H. C. C., Abbott, N. J., Burek, M., Cecchelli, R., Couraud, P., Deli, M. A., Förster, C., Galla, H. J., Romero, I. A., Shusta, E. V., Stebbins, M. J., Vandenhaute, E., Weksler, B. & Larsen, Birger Brodin, May 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 5, p. 862-90 29 p.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Transferrin receptor expression and role in transendothelial transport of transferrin in cultured brain endothelial monolayers

    Hersom, M., Helms, H. C., Pretzer, N., Andersen, C. G., Jensen, A. I., Severin, G., Nielsen, M. S., Holm, R. & Larsen, Birger Brodin, 24 Aug 2016, In: Molecular and Cellular Neuroscience. 76, p. 59-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Validation of reference genes for normalization of real-time quantitative PCR studies of gene expression in brain capillary endothelial cells cultured in vitro

    Hersom, M., Goldeman, C., Pretzer, N. & Larsen, Birger Brodin, Dec 2018, In: Molecular and Cellular Neuroscience. 93, p. 27-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The insulin receptor is expressed and functional in cultured blood-brain barrier endothelial cells, but does not mediate insulin entry from blood-to-brain

    Hersom, M., Helms, H. C., Schmalz, C., Pedersen, T. Å., Buckley, S. T. & Larsen, Birger Brodin, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 315, 4, p. E531-E542

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The insulin receptor is expressed and functional in blood-brain barrier endothelial cells, but does not mediate insulin entry from blood-to-brain

    Hersom, M. N. S., Helms, H. C. C., Pedersen, T., Buckley, S. & Larsen, Birger Brodin, 14 Sep 2016.

    Research output: Contribution to conference › Conference abstract for conference › Research

  11. Published

    Functional Insulin Receptor expression does not facilitate transendothelial passage of insulin in a bovine in vitro blood-brain barrier model

    Hersom, M. N. S., Helms, H. C. C., Pedersen, T., Buckley, S. & Larsen, Birger Brodin, 3 Mar 2016.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  12. Published

    Expression profiles of selected receptor systems in a bovine in vitro blood-brain barrier model

    Hersom, M. N. S., Helms, H. C. C., Nielsen, M. S., Holm, R. & Larsen, Birger Brodin, 10 Dec 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  13. Published

    Expression and functional activity of the efflux transporters BCRP and P-gp in bovine endothelial cells, co-cultured with rat astrocytes

    Hersom, M. N. S., Helms, H. C. C., Kuhlmann, L. B., Badolo, L. & Larsen, Birger Brodin, 2013. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  14. Published

    Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA-intermediates and produce ATP under hypoglycemic conditions

    Hinca, S. B., Salcedo, C., Wagner, A., Goldeman, C., Sadat, E., Aibar, M. M. D., Maechler, P., Larsen, Birger Brodin, Aldana, Blanca & Helms, H. C. C., 2021, In: Journal of Neurochemistry. 157, 6, p. 1861-1875

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier

    Holst, M. R., de Wit, N. M., Ozgür, Burak, Brachner, A., Hyldig, K., Appelt-Menzel, A., Sleven, H., Cader, Z., de Vries, H. E., Neuhaus, W., Jensen, A., Larsen, Birger Brodin & Nielsen, M. S., 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 82.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    ATP induces contraction of cultured brain capillary pericytes, via activation of P2Y type purinergic receptors

    Hørlyck, S., Cai, Changsi, Helms, H. C., Lauritzen, Martin & Larsen, Birger Brodin, 2021, In: American Journal of Physiology: Heart and Circulatory Physiology. 320, p. H699–H712 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Culture of brain capillary pericytes for cytosolic calcium measurements and calcium imaging studies

    Hørlyck, S., Helms, H. C. C. & Larsen, Birger Brodin, May 2020, In: Journal of Visualized Experiments. 159, p. 1-9 9 p., e61253.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Tanycytes Control the Hypothalamic Uptake and Metabolic Actions of Liraglutide

    Imbernon, M., Saponaro, C., Helms, H. C. C., Zubiaga, L., Bitsi, S., Duquenne, M., Tomas, A., Chen, S., Salem, V., Deligia, E., Gmyr, V., Denis, R., Kerr-Conte, J., Chao, D. H. M., Beiroa, D., Steals, B., Pattou, F., Pfrieger, F., Brodin, B., Jones, B. & 3 others, Luquet, S., Bonner, C. & Prevot, V., Jul 2021, In: Glia. 69, S1, p. E237-E237

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions

    Imbernon, M., Saponaro, C., Helms, H. C. C., Duquenne, M., Fernandois, D., Deligia, E., Denis, R. G. P., Chao, D. H. M., Rasika, S., Staels, B., Pattou, F., Pfrieger, F. W., Larsen, Birger Brodin, Luquet, S., Bonner, C. & Prevot, V., 2022, In: Cell Metabolism. 34, 7, p. 1054-1063.e7

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    PAT1 (SLC36A1) shows nuclear localization and affect growth of smooth muscle cells from rats

    Jensen, A., Figueiredo-Larsen, E. M., Holm, R., Broberg, M. L., Larsen, Birger Brodin & Nielsen, C. U., Jan 2014, In: A J P: Endocrinology and Metabolism (Online). 306, p. E65-E74

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    In vitro models for investigating the function of proton-coupled amino acid transporter 1 (PAT1, SLC36A19)

    Jensen, A., Larsen, Birger Brodin & Nielsen, C. U., 2010. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  22. Published

    ATP induce an increase in intracellular Ca2+ in pericytes of the blood-brain barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  23. Published

    Rises in intracellular calcium in primary brain pericytes are caused by ATP

    Jensen, S. H., Helms, H. C. C., Cai, Changsi, Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2016. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  24. Published

    Purinergic Signaling in Pericytes of the Blood-Brain Barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jul 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  25. Published

    ATP induce intracellular calcium rises in cultures of primary brain pericytes

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jun 2016.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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ID: 1299175