Andrea Heinz

Andrea Heinz

Associate Professor - Promotion Programme

ORCID: 0000-0002-8609-4460

Publication year:
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1 - 48 out of 48Page size: 500
  1. 2024
  2. E-pub ahead of print

    In Situ Imaging of Subcutaneous Drug Delivery Systems Using Microspatially Offset Low-Frequency Raman Spectroscopy

    Bērziņš, Kārlis, Czyrski, Grzegorz Sebastian, Aljabbari, Anas Samir Mohammad, Heinz, Andrea & Boyd, Ben, 11 Apr 2024, (E-pub ahead of print) In: Analytical Chemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Coaxial electrospinning of polycaprolactone: A design of experiments approach

    Gürtler, Anna-Lena, Linseisen, I., Grohganz, Holger & Heinz, Andrea, 2024, In: European Polymer Journal. 208, 11 p., 112886.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Elastin

    Rønnow, S. R., Kristensen, J. H., Thorlacius-Ussing, J., Karsdal, M. A. & Heinz, Andrea, 2024, Biochemistry of Collagens, Laminins and Elastin. 3 ed. Academic Press, p. 279-289

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  5. E-pub ahead of print

    Matrix metalloproteinase landscape in the imiquimod-induced skin inflammation mouse model

    Noddeland, H. K., Canbay, V., Lind, M., Savickas, S., Jensen, L. B., Petersson, K., Malmsten, Martin, Koch, J., Auf Dem Keller, U. & Heinz, Andrea, 2024, (E-pub ahead of print) In: Biochimie.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2023
  7. Published

    Design and characterization of matrix metalloproteinase-responsive hydrogels for the treatment of inflammatory skin diseases

    Noddeland, H. K., Lind, M., Jensen, L. B., Petersson, K., Skak-Nielsen, T., Larsen, F. H., Malmsten, Martin & Heinz, Andrea, 2023, In: Acta Biomaterialia. 157, p. 149-161

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Electrospun fibers for the treatment of skin diseases

    Gürtler, Anna-Lena, Rades, Thomas & Heinz, Andrea, 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 363, p. 621-640

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Protease-Responsive Hydrogel Microparticles for Intradermal Drug Delivery

    Noddeland, H. K., Lind, M., Petersson, K., Caruso, F., Malmsten, Martin & Heinz, Andrea, 2023, In: Biomacromolecules. 24, 7, p. 3203–3214

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2022
  11. Published

    In Situ Transformation of Electrospun Nanofibers into Nanofiber-Reinforced Hydrogels

    Martin, A., Nyman, J. N., Reinholdt, R., Cai, J., Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: Nanomaterials. 12, 14, 2437.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Zein-polycaprolactone core-shell nanofibers for wound healing

    Martin, A., Cai, J., Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: International Journal of Pharmaceutics. 621, 10 p., 121809.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2021
  14. Published

    Characterization of novel interactions with plasma membrane NEU1 reveals new biological functions for the elastin receptor complex in vascular diseases

    Tembely, D., Bocquet, O., Kawecki, C., Terryn, C., Schmelzer, C., Heinz, Andrea, Romier-Crouzet, B., Bennasroune, A., Blaise, S., Sartelet, H., Martiny, L., Duca, L. & Maurice, P., 2021, In: Atherosclerosis. 331, 1 p., E24.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  15. Published

    Elastic fibers during aging and disease

    Heinz, Andrea, 2021, In: Ageing Research Reviews. 66, 19 p., 101255.

    Research output: Contribution to journal › Review › Research › peer-review

  16. 2020
  17. Published

    Elastases and elastokines: elastin degradation and its significance in health and disease

    Heinz, Andrea, 2020, In: Critical Reviews in Biochemistry and Molecular Biology. 55, 3, p. 252-273 22 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Electrospinning Proteins for Wound Healing Purposes: Opportunities and Challenges

    Akhmetova, A. & Heinz, Andrea, 2020, In: Pharmaceutics. 13, 1, 22 p., 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Expression of elastolytic cathepsins in human skin and their involvement in age-dependent elastin degradation

    Panwar, P., Hedtke, T., Heinz, Andrea, Andrault, P., Hoehenwarter, W., Granville, D. J., Schmelzer, C. E. H. & Brömme, D., 2020, In: B B A - General Subjects. 1864, 5, 18 p., 129544.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Extracellular Matrix Stiffness and Composition Regulate the Myofibroblast Differentiation of Vaginal Fibroblasts

    Ruiz-Zapata, A. M., Heinz, Andrea, Kerkhof, M. H., van de Westerlo-van Rijt, C., Schmelzer, C. E. H., Stoop, R., Kluivers, K. B. & Oosterwijk, E., 2020, In: International Journal of Molecular Sciences . 21, 13, 15 p., 4762.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Highly Elastic and Water Stable Zein Microfibers as a Potential Drug Delivery System for Wound Healing

    Akhmetova, A., Lanno, G., Kogermann, K., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2020, In: Pharmaceutics. 12, 5, 19 p., 458.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Unique molecular networks: Formation and role of elastin cross-links

    Schmelzer, C. E. H., Hedtke, T. & Heinz, Andrea, 2020, In: IUBMB Life. 55, 3, p. 842-854 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  23. 2019
  24. Published

    A comprehensive map of human elastin cross-linking during elastogenesis

    Hedtke, T., Schräder, C. U., Heinz, Andrea, Hoehenwarter, W., Brinckmann, J., Groth, T. & Schmelzer, C. E. H., 2019, In: The F E B S Journal (Online). p. 3594-3610

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Identification of CD36 as a new interaction partner of membrane NEU1: potential implication in the pro-atherogenic effects of the elastin receptor complex

    Kawecki, C., Bocquet, O., Schmelzer, C. E. H., Heinz, Andrea, Ihling, C., Wahart, A., Romier, B., Bennasroune, A., Blaise, S., Terryn, C., Linton, K. J., Martiny, L., Duca, L. & Maurice, P., 2019, In: Cellular and molecular life sciences : CMLS. 76, 4, p. 791–807

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Lysyl oxidase-like 2 (LOXL2)-mediated cross-linking of tropoelastin

    Schmelzer, C. E. H., Heinz, Andrea, Troilo, H., Lockhart-Cairns, M. P., Jowitt, T. A., Marchand, M. F., Bidault, L., Bignon, M., Hedtke, T., Barret, A., McConnell, J. C., Sherratt, M. J., Germain, S., Hulmes, D. J. S., Baldock, C. & Muller, L., 2019, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 4, p. 5468-5481

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    MMP-14 degrades tropoelastin and elastin

    Miekus, N., Luise, C., Sippl, W., Baczek, T., Schmelzer, C. E. H. & Heinz, Andrea, 2019, In: Biochimie. p. 32-39

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2018
  29. Published

    Role for Cela1 in Postnatal Lung Remodeling and AAT-deficient Emphysema

    Joshi, R., Heinz, Andrea, Fan, Q., Guo, S., Monia, B., Schmelzer, C. E. H., Weiss, A. S., Batie, M., Parameshwaran, H. & Varisco, B. M., 8 Feb 2018, In: American Journal of Respiratory Cell and Molecular Biology. 59, 2, p. 167-178 0361OC .

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Degradation of tropoelastin and skin elastin by neprilysin

    Mora Huertas, A. C., Schmelzer, C. E. H., Luise, C., Sippl, W., Pietzsch, M., Hoehenwarter, W. & Heinz, Andrea, 2018, In: Biochimie. 146, p. 73-78 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Elastin is heterogeneously cross-linked

    Schräder, C. U., Heinz, Andrea, Majovsky, P., Karaman, B., Brinckmann, J., Sippl, W. & Schmelzer, C. E. H., 2018, In: The Journal of Biological Chemistry. 293, 39, p. 15107-15119

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Production of Elastin-Derived Peptides Contribute to the Development of Non-Alcoholic Steatohepatitis

    Romier, B., Ivaldi, C., Sartelet, H., Heinz, A., Schmelzer, C. E. H., Garnotel, R., Guillot, A., Jonquet, J., Bertin, E., Guéant, J-L., Alberto, J-M., Bronowicki, J-P., Amoyel, J., Hocine, T., Duca, L., Maurice, P., Bennasroune, A., Martiny, L., Debelle, L., Durlach, V. & 1 others, Blaise, S., 2018, In: Diabetes. 67, p. 1604-1615

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2016

  34. Prolyl hydroxylation in elastin is not random

    Schmelzer, C. E. H., Nagel, M. B. M., Dziomba, S., Merkher, Y., Sivan, S. S. & Heinz, Andrea, Oct 2016, In: B B A - Reviews on Cancer. 1860, 10, p. 2169-77 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Molecular-level insights into aging processes of skin elastin

    Mora Huertas, A. C., Schmelzer, C. E. H., Hoehenwarter, W., Heyroth, F. & Heinz, Andrea, 30 Aug 2016, In: Biochimie. 128-129, p. 163-73 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Elastins from patients with Williams-Beuren syndrome and healthy individuals differ on the molecular level

    Heinz, Andrea, Huertas, A. C. M., Schräder, C. U., Pankau, R., Gosch, A. & Schmelzer, C. E. H., Jul 2016, In: American Journal of Medical Genetics. Part A. 170, 7, p. 1832-42 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Cadmium toxicity investigated at the physiological and biophysical levels under environmentally relevant conditions using the aquatic model plant Ceratophyllum demersum

    Andresen, E., Kappel, S., Stärk, H., Riegger, U., Borovec, J., Mattusch, J., Heinz, Andrea, Schmelzer, C. E. H., Matoušková, Š., Dickinson, B. & Küpper, H., Jun 2016, In: New Phytologist. 210, 4, p. 1244-58 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2015
  39. Published

    Fingerprinting desmosine-containing elastin peptides

    Schräder, C. U., Heinz, Andrea, Majovsky, P. & Schmelzer, C. E. H., May 2015, In: Journal of the American Society for Mass Spectrometry. 26, 5, p. 762-73 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms

    Bultmann-Mellin, I., Conradi, A., Maul, A. C., Dinger, K., Wempe, F., Wohl, A. P., Imhof, T., Wunderlich, F. T., Bunck, A. C., Nakamura, T., Koli, K., Bloch, W., Ghanem, A., Heinz, Andrea, von Melchner, H., Sengle, G. & Sterner-Kock, A., Apr 2015, In: Disease models & mechanisms. 8, 4, p. 403-15 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2014
  42. Published

    Molecular-level characterization of elastin-like constructs and human aortic elastin

    Heinz, Andrea, Schräder, C. U., Baud, S., Keeley, F. W., Mithieux, S. M., Weiss, A. S., Neubert, R. H. H. & Schmelzer, C. E. H., Sep 2014, In: Matrix Biology. 38, p. 12-21 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. 2013
  44. Published

    Investigating the role of (2S,4R)-4-hydroxyproline in elastin model peptides

    Bochicchio, B., Laurita, A., Heinz, Andrea, Schmelzer, C. E. H. & Pepe, A., 9 Dec 2013, In: Biomacromolecules. 14, 12, p. 4278-88 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Elastin-derived peptides are new regulators of insulin resistance development in mice

    Blaise, S., Romier, B., Kawecki, C., Ghirardi, M., Rabenoelina, F., Baud, S., Duca, L., Maurice, P., Heinz, Andrea, Schmelzer, C. E. H., Tarpin, M., Martiny, L., Garbar, C., Dauchez, M., Debelle, L. & Durlach, V., Nov 2013, In: Diabetes. 62, 11, p. 3807-16 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    In vitro cross-linking of elastin peptides and molecular characterization of the resultant biomaterials

    Heinz, Andrea, Ruttkies, C. K. H., Jahreis, G., Schräder, C. U., Wichapong, K., Sippl, W., Keeley, F. W., Neubert, R. H. H. & Schmelzer, C. E. H., Apr 2013, In: B B A - Reviews on Cancer. 1830, 4, p. 2994-3004 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2012
  48. Published

    Does human leukocyte elastase degrade intact skin elastin?

    Schmelzer, C. E. H., Jung, M. C., Wohlrab, J., Neubert, R. H. H. & Heinz, Andrea, Nov 2012, In: F E B S Journal. 279, 22, p. 4191-200 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Longevity of elastin in human intervertebral disc as probed by the racemization of aspartic acid

    Sivan, S., Van El, B., Merkher, Y., Schmelzer, C. E. H., Zuurmond, A., Heinz, Andrea, Wachtel, E., Varga, P., Lazary, A., Brayda-Bruno, M. & Maroudas, A., Oct 2012, In: B B A - Reviews on Cancer. 1820, 10, p. 1671-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The action of neutrophil serine proteases on elastin and its precursor

    Heinz, Andrea, Jung, M. C., Jahreis, G., Rusciani, A., Duca, L., Debelle, L., Weiss, A. S., Neubert, R. H. H. & Schmelzer, C. E. H., Jan 2012, In: Biochimie. 94, 1, p. 192-202 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. 2011
  52. Published

    Structure and activity of Aspergillus nidulans copper amine oxidase

    McGrath, A. P., Mithieux, S. M., Collyer, C. A., Bakhuis, J. G., van den Berg, M., Sein, A., Heinz, Andrea, Schmelzer, C., Weiss, A. S. & Guss, J. M., 28 Jun 2011, In: Biochemistry. 50, 25, p. 5718-30 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Insights into the degradation of human elastin by matrilysin-1

    Heinz, Andrea, Taddese, S., Sippl, W., Neubert, R. H. H. & Schmelzer, C. E. H., Feb 2011, In: Biochimie. 93, 2, p. 187-94 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2010
  55. Published

    Degradation of tropoelastin by matrix metalloproteinases--cleavage site specificities and release of matrikines

    Heinz, Andrea, Jung, M. C., Duca, L., Sippl, W., Taddese, S., Ihling, C., Rusciani, A., Jahreis, G., Weiss, A. S., Neubert, R. H. H. & Schmelzer, C. E. H., Apr 2010, In: F E B S Journal. 277, 8, p. 1939-56 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    MMP-12 catalytic domain recognizes and cleaves at multiple sites in human skin collagen type I and type III

    Taddese, S., Jung, M. C., Ihling, C., Heinz, Andrea, Neubert, R. H. H. & Schmelzer, C. E. H., Apr 2010, In: B B A - Reviews on Cancer. 1804, 4, p. 731-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2009
  58. Published

    Analysis of solid-state transformations of pharmaceutical compounds using vibrational spectroscopy

    Heinz, Andrea, Strachan, C. J., Gordon, K. C. & Rades, Thomas, Aug 2009, In: The Journal of pharmacy and pharmacology. 61, 8, p. 971-88 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  59. Published

    Better understanding of dissolution behaviour of amorphous drugs by in situ solid-state analysis using Raman spectroscopy

    Savolainen, M., Kogermann, K., Heinz, Andrea, Aaltonen, J., Peltonen, L., Strachan, C. & Yliruusi, J., Jan 2009, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 71, 1, p. 71-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Understanding the solid-state forms of fenofibrate - a spectroscopic and computational study

    Heinz, Andrea, Gordon, K. C., McGoverin, C. M., Rades, Thomas & Strachan, C. J., 2009, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 71, 1, p. 100-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. 2008
  62. Published

    Characterizing an amorphous system exhibiting trace crystallinity: A case study with saquinavir

    Heinz, Andrea, Strachan, C. J., Atassi, F., Gordon, K. C. & Rades, Thomas, Jan 2008, In: Crystal Growth & Design. 8, 1, p. 119-127

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. 2007
  64. Published

    Quantifying ternary mixtures of different solid-state forms of indomethacin by Raman and near-infrared spectroscopy

    Heinz, Andrea, Savolainen, M., Rades, Thomas & Strachan, C. J., 2007, In: European Journal of Pharmaceutical Sciences. 32, 3, p. 182-192 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Screening for differences in the amorphous state of indomethacin using multivariate visualization

    Savolainen, M., Heinz, Andrea, Strachan, C., Gordon, K. C., Yliruusi, J., Rades, Thomas & Sandler, N., 2007, In: European Journal of Pharmaceutical Sciences. 30, 2, p. 113-123

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 165030651