Department of Pharmacy > Research > Section of Pharmaceutical Design and Drug Delivery > Drug Transporters in A...
Drug Transporters in ADME group
This group deals with the role of membrane transporters in Absorption, Distribution, Metabolism and Excretion (ADME) of drugs in the body.
Projects
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Drug absorption and drug/drug and drug/food interactions via intestinal amino acid and peptide transporters
Investigations of drug absorption via membrane transport proteins in the small intestine. Drug transport and drug/drug or drug/food interactions are evaluated.
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Biosimulation of transporter/drug interactions
Intestinal uptake and efflux of drug compounds is simulated in computer models, on the basis of data from transport and uptake experiments.
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Drug delivery across the blood-brain barrier
Predictive in vitro models of the blood brain barrier are generated from primary bovine cell cultures. CNS drug uptake is being characterized.
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