Department of Pharmacy > Research > Section of Analytical Biosciences > Microscale Analytical ...

Microscale Analytical Systems Group

In the Microscale Analytical Systems group, we deal with different areas within the field of bio-chemical microdevices. The miniaturization of biological assays has considerable advantages. Microfluidic devices, for example, offer the potential for increased experimental throughput while minimizing sample and reagent consumption. Microfluidic biochips can be used to easily integrate sample preparation steps, such as pre-concentration, protein digestion, separation, labeling and derivatization. This high level of integration reduces analysis time as well as the potential for manipulation errors, sample losses and contaminations. Our objective is to develop novel microscale platforms for the analysis of compounds of pharmaceutical interest. The projects in the Microscale Analytical Systems group are highly multidisciplinary.

• Microfluidic-based Structural Analysis of Protein Fibrils

  In collaboration with the BioSAXS Research group at the Department of Drug Design and Pharmacology.
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• Thiol-ene based protein biochips: A novel, versatile tool for bioanalytical research

  We are investigating the high potential of thiol-ene polymers as a biochip substrate for the in-vitro characterization of biochemical activities.
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• Evaluation and optimisation of 3D patterning for fabrication of polymer-based microfluidic devices

  We are using an automated 3D patterning technique for the prototyping of biochemical assays with light curable resins.
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