Pharmaceuticals, processes and products

  1. 2024
  2. Published

    Anti-plasticizing effect of water on prilocaine and lidocaine: the role of the hydrogen bonding pattern

    Xu, X., Grohganz, Holger & Rades, Thomas, 2024, In: Physical Chemistry Chemical Physics. 26, p. 14149-14159

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Assessment of subvisible particles in biopharmaceuticals with image feature extraction and machine learning

    Maharjan, R., Lee, J. C., Bøtker, Johan Peter, Kim, K. H., Kim, N. A., Jeong, S. H. & Rantanen, Jukka, 2024, In: Chemometrics and Intelligent Laboratory Systems. 245, 10 p., 105061.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Binder jetting 3D printing in fabricating pharmaceutical solid products for precision medicine

    Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2024, In: Basic & clinical pharmacology & toxicology. 134, 3, p. 325-332

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Co-spray dried inhalable composite powders of ciprofloxacin and alginate oligosaccharide as anti-biofilm therapy

    Zhang, L., Bera, H., Guo, Y., Shi, C., Ulrik Lind, J., Radeke, C., Wang, J., Wang, H., Zhao, X., Cun, D. & Yang, Mingshi, 2024, In: International Journal of Pharmaceutics. 654, 12 p., 123949.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Compaction Properties of Particulate Proteins in Binary Powder Mixtures with Common Excipients

    Holmfred, Else Skovgaard, Hirschberg, C. & Rantanen, Jukka, 2024, In: Pharmaceutics. 16, 1, 11 p., 19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Destabilization of Indomethacin-Paracetamol Co-Amorphous Systems by Mechanical Stress

    Di, Rong, Grohganz, Holger & Rades, Thomas, 2024, In: Pharmaceutics. 16, 15 p., 67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Exploring the effect of protein secondary structure on the solid state and physical stability of protein-based amorphous solid dispersions

    Zhuo, Xuezhi, Ochner, J., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 198, 8 p., 114274.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Impact of drug load and polymer molecular weight on the 3D microstructure of printed tablets

    Larsen, B. S., Kissi, E., Nogueira, L. P., Genina, Natalja & Tho, I., 2024, In: European Journal of Pharmaceutical Sciences. 192, 11 p., 106619.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Long-acting inhaled medicines: Present and future

    Zhang, Chengqian, D'Angelo, D., Buttini, F. & Yang, Mingshi, 2024, In: Advanced Drug Delivery Reviews. 204, 19 p., 115146.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Mannose-Decorated Solid-Lipid Nanoparticles for Alveolar Macrophage Targeted Delivery of Rifampicin

    Bera, H., Zhao, C., Tian, X., Cun, D. & Yang, Mingshi, 2024, In: Pharmaceutics. 16, 3, 12 p., 429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation

    Mortensen, Janni Støvring, Bohr, S. S. R., Krog, Lasse Skjoldborg, Bøtker, Johan Peter, Kapousidou, V., Saaby, Lasse, Hatzakis, Nikos, Nielsen, Hanne Mørck, Nguyen, Duc Ninh & Rønholt, Stine, 2024, In: Scientific Reports. 14, 1, 17 p., 7665.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Sialic Acid Conjugate-Modified Cationic Liposomal Paclitaxel for Targeted Therapy of Lung Metastasis in Breast Cancer: What a Difference the Cation Content Makes

    Sun, W., Han, C., Ge, R., Jiang, X., Wang, Y., Han, Y., Wang, N., Song, Y., Yang, Mingshi, Chen, G. & Deng, Y., 2024, In: Molecular Pharmaceutics. 21, 4, p. 1625-1638

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Utilizing the allyl-terminated copolymer methoxy(poly(ethylene glycol))-block-poly(jasmine lactone) in the development of amorphous solid dispersions: A comparative study of functionalized and non-functionalized polymer

    Di, Rong, Bansal, K. K., Rosenholm, J. M., Grohganz, Holger & Rades, Thomas, 2024, In: International Journal of Pharmaceutics. 657, 12 p., 124175.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2023
  16. Published

    20(R)-ginsenoside Rg3-loaded polyurethane/marine polysaccharide based nanofiber dressings improved burn wound healing potentials

    Guo, X., Xiu, F., Bera, H., Abbasi, Y. F., Chen, Y., Si, L., Liu, P., Zhao, C., Tang, X., Feng, Y., Cun, D., Zhao, X. & Yang, Mingshi, 2023, In: Carbohydrate Polymers. 317, 121085.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Assembly Rules and Dehydration Mechanism of an Unconventional Hydrate: On the Complexity of the Hydrates of Creatine Phosphate Sodium

    Dai, J., Zhou, L., Yang, W., Rantanen, Jukka & Yin, Q., 2023, In: Crystal Growth and Design. 23, 3, p. 1987-2000

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Co-administration of Intravenous Drugs: Rapidly Troubleshooting the Solid Form Composition of a Precipitate in a Multi-drug Mixture Using On-Site Raman Spectroscopy

    Nilsson, N., Nezvalova-Henriksen, K., Bøtker, Johan Peter, Højmark Andersen, N., Strøm Larsen, B., Rantanen, Jukka, Tho, I. & Brustugun, J., 2023, In: Molecular Pharmaceutics. 20, 6, p. 2853–2863

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Products

    Wang, Y., Genina, Natalja, Mullertz, Anette & Rantanen, Jukka, 2023, In: Journal of Pharmaceutical Sciences. 112, 2, p. 506-512

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Comment on the article Symmetry and chirality in crystals

    Rekis, T., 2023, In: Journal of Applied Crystallography. 56, p. 322-323

    Research output: Contribution to journalComment/debateResearch

  21. Published

    Compaction Behavior of Co-Amorphous Systems

    Sørensen, C. M., Rantanen, Jukka & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 3, 12 p., 858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Comparative evaluation of three methods for quantifying tablet brittleness

    Møller-Sonnergaard, Jørn, 2023, In: Pharmaceutical Development and Technology. 28, 8, p. 719-723

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Comparative study between a gravity-based and peristaltic pump for intravenous infusion with respect to the generation of proteinaceous microparticles

    Hada, S., Ji, S., Lee, Y. N., Kim, K. H., Maharjan, R., Kim, N. A., Rantanen, Jukka & Jeong, S. H., 2023, In: International Journal of Pharmaceutics. 642, 123091.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Comparative study of lipid nanoparticle-based mRNA vaccine bioprocess with machine learning and combinatorial artificial neural network-design of experiment approach

    Maharjan, R., Hada, S., Eun Lee, J., Han, H., Hyun Kim, K., Jin Seo, H., Foged, Camilla & Hoon Jeong, S., 2023, In: International Journal of Pharmaceutics. 640, 13 p., 123012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Corrigendum to "Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites" [J. Colloid Interface Sci. 606(Part 2) (2022) 1928-1939]

    Zhou, X., Galparsoro, D. F., Madsen, Anders Østergaard, Vetri, V., van de Weert, Marco, Nielsen, Hanne Mørck & Foderà, Vito, 2023, In: Journal of Colloid and Interface Science. 640, p. 917

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Donepezil accelerates the release of PLGA microparticles via catalyzing the polymer degradation regardless of the end groups and molecular weights

    Quan, P., Guo, W., LinYang, Cun, D. & Yang, Mingshi, 2023, In: International Journal of Pharmaceutics. 632, 7 p., 122566.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Drug Combination of Ciprofloxacin and Polymyxin B for the Treatment of Multidrug-Resistant Acinetobacter baumannii Infections: A Drug Pair Limiting the Development of Resistance

    Wang, J., Stegger, M., Moodley, Arshnee & Yang, Mingshi, 2023, In: Pharmaceutics. 15, 3, 18 p., 720.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Engineering Transferrin-Decorated Pullulan-Based Prodrug Nanoparticles for Redox Responsive Paclitaxel Delivery to Metastatic Lung Cancer Cells

    Zhao, X., Guo, H., Bera, H., Jiang, H., Chen, Y., Guo, X., Tian, X., Cun, D. & Yang, Mingshi, 2023, In: ACS applied materials & interfaces. 15, 3, p. 4441–4457

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Evaluating the pharmacokinetics of intrapulmonary administered ciprofloxacin solution for respiratory infections using in vivo and in silico PBPK rat model studies

    Shi, C., Ignjatović, J., Wang, J., Guo, Y., Zhang, L., Cvijić, S., Cun, D. & Yang, Mingshi, 2023, In: Chinese Chemical Letters. 34, 1, 5 p., 107463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Exploring the Solid-State Landscape of Carbamazepine during Dehydration: A Low Frequency Raman Spectroscopy Perspective

    Remoto, P. I. I. I. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2023, In: Pharmaceutics. 15, 5, 15 p., 1526.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    In Vitro and In Vivo Evaluation of Inhalable Ciprofloxacin Sustained Release Formulations

    Shi, C., Guo, K., Zhang, L., Guo, Y., Feng, Y., Cvijić, S., Cun, D. & Yang, Mingshi, 2023, In: Pharmaceutics. 15, 9, 13 p., 2287.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Inhaled RNA drugs to treat lung diseases: Disease-related cells and nano–bio interactions

    Zhang, M., Lu, H., Xie, L., Liu, X., Cun, D. & Yang, Mingshi, 2023, In: Advanced Drug Delivery Reviews. 203, 115144.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Magistral Compounding with 3D Printing: A Promising Way to Achieve Personalized Medicine

    Beer, N., Kaae, Susanne, Genina, Natalja, Kälvemark Sporrong, Sofia, Leonardo Alves, T., Hoebert, J., De Bruin, M. L. (. & Hegger, I., 2023, In: Therapeutic Innovation & Regulatory Science. 57, p. 26–36

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Mucoadhesive chitosan- and cellulose derivative-based nanofiber-on-foam-on-film system for non-invasive peptide delivery

    Stie, Mai Bay, Öblom, H., Hansen, Anders Christian Nørgaard, Jacobsen, Jette, Chronakis, I. S., Rantanen, Jukka, Nielsen, Hanne Mørck & Genina, Natalja, 2023, In: Carbohydrate Polymers. 303, 120429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Recent advances in pH/enzyme-responsive polysaccharide-small-molecule drug conjugates as nanotherapeutics

    Abbasi, Y. F., Bera, H., Cun, D. & Yang, Mingshi, 2023, In: Carbohydrate Polymers. 312, 120797.

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Role of dispersion enhancer selection in the development of novel tratinterol hydrochloride dry powder inhalation formulations

    Liu, T., Tong, S., Liao, Q., Pan, L., Cheng, M., Rantanen, Jukka, Cun, D. & Yang, Mingshi, 2023, In: International Journal of Pharmaceutics. 635, 8 p., 122702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Terahertz time-domain spectroscopy for the investigation of tablets prepared from roller compacted granules

    Anuschek, M., Skelbæk-Pedersen, A. L., Kvistgaard Vilhelmsen, T., Skibsted, E., Zeitler, J. A. & Rantanen, Jukka, 2023, In: International Journal of Pharmaceutics. 642, 123165.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The structure of magnesium stearate trihydrate determined from a micrometre-sized single crystal using a microfocused synchrotron X-ray beam

    Herzberg, M., Rekis, T., Støttrup Larsen, A., Gonzalez, A., Rantanen, Jukka & Madsen, Anders Østergaard, 2023, In: Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 79, p. 330-335

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Towards simultaneous determination of tablet porosity and height by terahertz time-domain reflection spectroscopy

    Anuschek, M., Kvistgaard Vilhelmsen, T., Axel Zeitler, J. & Rantanen, Jukka, 2023, In: International Journal of Pharmaceutics. 646, 10 p., 123424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Unleashing the healing potential: Exploring next-generation regenerative protein nanoscaffolds for burn wound recovery

    Si, L., Guo, X., Bera, H., Chen, Y., Xiu, F., Liu, P., Zhao, C., Abbasi, Y. F., Tang, X., Foderà, Vito, Cun, D. & Yang, Mingshi, 2023, In: Asian Journal of Pharmaceutical Sciences. 18, 6, 13 p., 100856.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Unveiling polyamorphism and polyamorphic interconversions in pharmaceuticals: the peculiar case of hydrochlorothiazide

    Batista Martins, Inês Catarina, Larsen, A. S., Madsen, Anders Østergaard, Aalling-Frederiksen, Olivia, Correia, A., Jensen, Kirsten Marie Ørnsbjerg, Jeppesen, H. S. & Rades, Thomas, 2023, In: Chemical Science. 14, 41, p. 11447-11455 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2022
  43. Published

    A Simplified Model Structure for Compression Characterization of Pharmaceutical Tablets

    Møller-Sonnergaard, Jørn, 2022, In: Journal of Pharmaceutical Sciences. 111, 11, p. 3088-3095

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A generalized image analytical algorithm for investigating tablet disintegration

    Wu, J. X., Balantic, E., van der Berg, Franciscus Winfried J, Rantanen, Jukka, Nissen, B. & Friderichsen, A. V., 2022, In: International Journal of Pharmaceutics. 623, 11 p., 121847.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Additive Manufacturing of Solid Products for Oral Drug Delivery Using Binder Jetting Three-Dimensional Printing

    Wang, Y., Mullertz, Anette & Rantanen, Jukka, 2022, In: AAPS PharmSciTech. 23, 6, 196.

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Additive manufacturing in respiratory sciences – Current applications and future prospects

    Bock, S., Rades, Thomas, Rantanen, Jukka & Scherließ, R., 2022, In: Advanced Drug Delivery Reviews. 186, 14 p., 114341.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Airway epithelial cell-specific delivery of lipid nanoparticles loading siRNA for asthma treatment

    Zhang, M., Jiang, H., Wu, L., Lu, H., Bera, H., Zhao, X., Guo, X., Liu, X., Cun, D. & Yang, Mingshi, 2022, In: Journal of Controlled Release. 352, p. 422-437

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections

    Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, Claus Ernst, Høiby, Niels & Yang, Mingshi, 2022, In: International Journal of Pharmaceutics. 616, 121507.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Controlling desolvation through polymer-assisted grinding

    Terban, M. W., Madhau, L., Cruz-Cabeza, A. J., Okeyo, P. O., Etter, M., Schulz, A., Rantanen, Jukka, Dinnebier, R. E., Billinge, S. J. L., Moneghini, M. & Hasa, D., 2022, In: CrystEngComm. 24, 12, p. 2305-2313

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Dynamics and disorder: on the stability of pyrazinamide polymorphs

    Hoser, A. A., Rekis, T. & Madsen, Anders Østergaard, 2022, In: Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 78, p. 416-424

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Effect of pH on the Surface Layer of Molecular Crystals at the Solid-Liquid Interface

    Herzberg, M., Larsen, A. S., Hassenkam, Tue, Madsen, Anders Østergaard & Rantanen, Jukka, 2022, In: Molecular Pharmaceutics. 19, 5, p. 1598–1603

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Elucidating the Dehydration Mechanism of Nitrofurantoin Monohydrate II Using Low-Frequency Raman Spectroscopy

    Remoto, P. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2022, In: Crystal Growth and Design. 22, 4, p. 2733-2741

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    In-line Fluorescence Spectroscopy for Quantification of Low Amount of Active Pharmaceutical Ingredient

    Sørensen, D. H., Christensen, N. P. A., Skibsted, E., Rantanen, Jukka & Rinnan, Åsmund, 2022, In: Journal of Pharmaceutical Sciences. 111, 9, p. 2406-2410

    Research output: Contribution to journalJournal articleResearchpeer-review

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