Protein Formulation and Biophysics
Protein-based drugs have high potential, both financially and medically. One of the most important challenges for these drugs to meet their potential is the limited physicochemical stability of proteins in solution.
The Protein Formulation and Biophysics group studies the mechanisms of destabilisation of proteins due to interactions with their surroundings, with focus on protein aggregation and fibrillation, and adsorption. The effect of environmental changes on these processes, e.g. by introducing formulation additives, is also studied.
The group employs a range of advanced analytical techniques, combined with theoretical modeling. The group is an interdisciplinary team comprised of a pharmacist, a chemist and a physicist as staff members.