30 January 2017
Large Grant for Research into Biopharmaceuticals
A research project at Department of Pharmacy is granted DKK 60 million from the Novo Nordisk Foundation Challenge Programme. The grant is given to Professor Hanne Mørck Nielsen who will conduct research into the development of biopharmaceuticals which may be taken orally.
Professor Hanne Mørck Nielsen at the Department of Pharmacy is granted DKK 60 million from the Novo Nordisk Foundation Challenge Programme.
The Novo Nordisk Foundation describes the project as follows:
"New knowledge on transporting drugs in the body
Many life-threatening diseases are controlled effectively by injecting peptide- and protein-based drugs known as biopharmaceuticals. Administering these drugs as tablets would be very advantageous, especially for people with chronic diseases and those who need to take the medicine frequently.
However, the challenge is that these drugs are broken down in the intestines, and the amount absorbed by the intestines varies tremendously. Delivering the drugs throughout the body following oral administration is therefore enormously challenging, and there are still no general methods for solving this problem.
"The project focuses on solving the challenges of drug delivery by developing a better and more detailed understanding of how peptide- and protein-based drugs integrate with and are transported across the intestinal membrane and arrive at their target areas. To move towards achieving this ambitious target, the project will develop new unique drug-delivery concepts, technologies and methods. This major project involves advanced chemistry, nanorobots and visualizing the transport of drugs in the body. This will enable us to design and study systems for oral drug delivery of biopharmaceuticals," says Hanne Mørck Nielsen."
About the Novo Nordisk Foundation Challenge Programme
The Novo Nordisk Foundation Challenge Programme aims to support and promote world-class research that focuses on finding answers to challenges in global technology or health.
Aimed at leading researchers, the Foundation Programme awards grants of DKK 60 million over 6 years to research groups, thereby enabling them to have the funds to carry out in-depth research on a specific theme over a long time frame.
To ensure that the best project proposals and research teams are considered, the Foundation wards the grants through calls for applications in open competition. A specially created expert committee assesses the applicants.