Kasper Dyrberg Rand
Professor
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A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life
Jensen, P. F., Schoch, A., Larraillet, V., Hilger, M., Schlothauer, T., Emrich, T. & Rand, Kasper Dyrberg, Mar 2017, In: Molecular and Cellular Proteomics. 16, 3, p. 451-456 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry
Leurs, U., Lohse, B., Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In: Analytical Chemistry. 86, 23, p. 11734-11741 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The dopamine transporter antiports potassium to increase the uptake of dopamine
Schmidt, S. G., Malle, M. G., Nielsen, A. K., Bohr, S. S., Pugh, Ciara Frances, Nielsen, Jeppe Cederholm, Poulsen, I. H., Rand, Kasper Dyrberg, Hatzakis, Nikos & Loland, Claus Juul, 2022, In: Nature Communications. 13, 1, 12 p., 2446.Research output: Contribution to journal › Journal article › Research › peer-review
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Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb
Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Filliben, J. J., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J. D., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R. K. & 17 others, , 2019, In: Analytical Chemistry. 91, 11, p. 7336-7345Research output: Contribution to journal › Journal article › Research › peer-review
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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Masson, G. R., Burke, J. E., Ahn, N. G., Anand, G. S., Borchers, C., Brier, S., Bou-Assaf, G. M., Engen, J. R., Englander, S. W., Faber, J., Garlish, R., Griffin, P. R., Gross, M. L., Guttman, M., Hamuro, Y., Heck, A. J. R., Houde, D., Iacob, R. E., Jorgensen, T. J. D., Kaltashov, I. A. & 20 others, , Jul 2019, In: Nature Methods. 16, 7, p. 595-602Research output: Contribution to journal › Journal article › Research › peer-review
Gas-phase fragmentation of peptides by MALDI in-source decay with limited amide hydrogen (1H/2H) scrambling
Bache, N., Rand, Kasper Dyrberg, Roepstorff, P. & Jørgensen, T., 2008, In: Analytical Chemistry. 80, 16, p. 6431-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
The origins of enhanced activity in factor VIIa analogs and the interplay between key allosteric sites revealed by hydrogen exchange mass spectrometry
Rand, Kasper Dyrberg, Andersen, M., Olsen, O. H., Jørgensen, T., Ostergaard, H., Jensen, O., Stennicke, H. R. & Persson, E., 2008, In: Journal of Biological Chemistry. 283, 19, p. 13378-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Allosteric activation of coagulation factor VIIa visualized by hydrogen exchange
Rand, Kasper Dyrberg, Jørgensen, T., Olsen, Ole, Persson, E., Jensen, O., Stennicke, H. R. & Andersen, M., 2006, In: Journal of Biological Chemistry. 281, 32, p. 23018-24 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by hydrogen exchange mass spectrometry
Hebling, C. M., Morgan, C. R., Stafford, D. W., Jorgenson, J. W., Rand, Kasper Dyrberg & Engen, J. R., 2010, In: Analytical Chemistry. 82, 13, p. 5415-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pinpointing changes in higher-order protein structure by hydrogen/deuterium exchange coupled to electron transfer dissociation mass spectrometry
Rand, Kasper Dyrberg, 15 Mar 2013, In: International Journal of Mass Spectrometry. 338, p. 2-10 9 p.Research output: Contribution to journal › Review › Research › peer-review
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A novel sensitive sheathless CE-MS device for peptide and protein analysis
Nguyen, T. T. T. N., Petersen, Nickolaj J. & Rand, Kasper Dyrberg, 8 Jun 2016. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Conformational destabilization of Immunoglobulin G increases the low pH-binding affinity with the Neonatal Fc Receptor
Walters, B. T., Jensen, P. F., Larraillet, V., Lin, K., Patapoff, T., Schlothauer, T., Rand, Kasper Dyrberg & Zhang, J., 22 Jan 2016, In: Journal of Biological Chemistry. 291, 4, p. 1817-1825 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Side-chain moieties from the N-terminal region of Aβ are Involved in an oligomer-stabilizing network of interactions
Przygońska, K., Poznański, J., Mistarz, U. H., Rand, Kasper Dyrberg & Dadlez, M., 6 Aug 2018, In: PLoS One. 13, 8, p. 1-25 25 p., e0201761.Research output: Contribution to journal › Journal article › Research › peer-review
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Measuring the hydrogen/deuterium exchange of proteins at high spatial resolution by mass spectrometry: overcoming gas-phase hydrogen/deuterium scrambling
Rand, Kasper Dyrberg, Zehl, M. & Jørgensen, T. J. D., 21 Oct 2014, In: Accounts of Chemical Research. 47, 10, p. 3018-27 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry
Jensen, P. F., Larraillet, V., Schlothauer, T., Kettenberger, H., Hilger, M. & Rand, Kasper Dyrberg, Jan 2015, In: Molecular and Cellular Proteomics. 14, 1, p. 148-61 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Basis of the Mechanisms Controlling MASTL
Hermida, D., Mortuza, G. B., Pedersen, A., Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343Research output: Contribution to journal › Journal article › Research › peer-review
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Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS
Möller, I. R., Merkle, P. S., Calugareanu, D., Comamala, G., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2020, In: Journal of Proteomics. 225, 103845.Research output: Contribution to journal › Journal article › Research › peer-review
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PNGase H+ variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N‐glycans and HDX‐MS analysis of glycoproteins.
Guo, R., Zhang, T., Lambert, Thomas Ole Tandrup, Wang, T., Voglmeir, J., Rand, Kasper Dyrberg & Liu, L., 2022, In: Rapid Communications in Mass Spectrometry. 36, 21, 9 p., e9376.Research output: Contribution to journal › Journal article › Research › peer-review
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Epitope Mapping of Polyclonal Antibodies by Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS)
Ständer, S., Grauslund, L. R., Scarselli, M., Norais, N. & Rand, Kasper Dyrberg, 2021, In: Analytical Chemistry. 93, 34, p. 11669–11678Research output: Contribution to journal › Journal article › Research › peer-review
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Probing the impact of temperature and substrates on the conformational dynamics of the Neurotransmitter:Sodium symporter LeuT
Calugareanu, D., Möller, I. R., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2022, In: Journal of Molecular Biology. 434, 2, 15 p., 167356.Research output: Contribution to journal › Journal article › Research › peer-review
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An intact C-terminal end of albumin is required for long serum half-life
Nilsen, J., Trabjerg, E., Grevys, A., Azevedo, C., Brennan, S. O., Stensland, M., Wilson, J., Sand, K. M. K., Bern, M., Dalhus, B., Roopenian, D. C., Sandlie, I., Rand, Kasper Dyrberg & Andersen, J. T., Dec 2019, p. 19. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization
Kim, M., Sun, Z. J., Rand, Kasper Dyrberg, Shi, X., Song, L., Cheng, Y., Fahmy, A. F., Majumdar, S., Ofek, G., Yang, Y., Kwong, P. D., Wang, J., Engen, J. R., Wagner, G. & Reinherz, E. L., 2011, In: Nature Structural and Molecular Biology. 18, 11, p. 1235-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ETD in a traveling wave ion guide at tuned Z-spray ion source conditions allows for site-specific hydrogen/deuterium exchange measurements
Rand, Kasper Dyrberg, Pringle, S. D., Morris, M., Engen, J. R. & Brown, J. M., 2011, In: Journal of The American Society for Mass Spectrometry. 22, 10, p. 1784-1793Research output: Contribution to journal › Journal article › Research › peer-review
Conformational dynamics of the Escherichia coli DNA polymerase manager proteins UmuD and UmuD'
Fang, J., Rand, Kasper Dyrberg, Silva, M. C., Wales, T. E., Engen, J. R. & Beuning, P. J., 2010, In: Journal of Molecular Biology. 398, 1, p. 40-53 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Conformational transitions in the membrane scaffold protein of phospholipid bilayer nanodiscs
Morgan, C. R., Hebling, C. M., Rand, Kasper Dyrberg, Stafford, D. W., Jorgenson, J. W. & Engen, J. R., 2011, In: Molecular and Cellular Proteomics. 10, 9, p. M111.010876Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34783804
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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Research output: Contribution to journal › Journal article › Research › peer-review
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236
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The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study
Research output: Contribution to journal › Journal article › Research › peer-review
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227
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Research output: Contribution to journal › Journal article › Research › peer-review
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